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Quetiapine

Quetiapine (/kwɪˈtaɪ.əpiːn/ kwi-TY-ə-peen), sold under the brand name Seroquel among others, is an atypical antipsychotic medication used in the treatment of schizophrenia, bipolar disorder, and major depressive disorder.

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Key facts & relationships

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N05AH04 (WHO)
Bioavailability
100%
CAS Number
111974-69-7 Y
ChEBI
CHEBI:8707 Y

Topics to explore

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Overview

Medical uses

Adverse effects

Overdose

Pharmacology

Chemistry

History

Society and culture

Advanced semantic analysis

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Map overview Semantic statistics

Quetiapine

Nodes201
Edges200
Triples141
Avg. degree1.99
Density0.00995
Components1

How this topic connects Entity context

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Quetiapine

Top relations

related to Pharmacodynamics · 17
Quetiapine → D2, D3, D4, D5, Dopamine D1, H1, HT1A, HT1B, HT1D, HT1E, HT1F, HT2A, HT2B, HT2C, HT3, HT6, HT7
related to Sustained-release · 16
Quetiapine → American, AstraZeneca, August, Canada, During, European Union, FDA, However, In May, November, Q2, Seroquel XR, Seroquel XR's, The, United States, United States FDA
related to Insomnia · 10
Quetiapine → CITooltip, Danish, Doses, Increases, Laboratory, LDL-C, Regardless, The, These, Z-drugs
related to Lawsuits · 8
Quetiapine → According, AstraZeneca, Department, In April, Justice, Multiple, Seroquel, United States Department
related to Regulatory status · 7
Quetiapine → Drug Administration, FDA, Food, In, United States, US FDA, XR
Legal status · 6
Quetiapine → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), CA: ℞-only, NZ: Prescription only, UK: POM (Prescription only), US: ℞-only
related to Abuse potential · 6
Quetiapine → In, It, Q-ball, The, To, While
related to Major depressive disorder · 6
Quetiapine → Australia, Australian Pharmaceutical Benefits Scheme, In, MDD, United Kingdom, United States
has effect · 4
Quetiapine → Dry, Extended, Sources, XR
related to Others · 4
Quetiapine → It, Owing, Parkinson's, Tourette

Important terminology Word statistics

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Important terminology

treatment schizophrenia antipsychotics effects disorder seroquel clozapine drug used low use insomnia bipolar united atypical antipsychotic blood may side states

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Quetiapine3D model (JSmol)Interactive image1.00infobox
QuetiapineAHFS/Drugs.comMonograph1.00infobox
QuetiapineATC codeN05AH04 (WHO)1.00infobox
QuetiapineBioavailability100%1.00infobox
QuetiapineCAS Number111974-69-7 Y1.00infobox
QuetiapineChEBICHEBI:8707 Y1.00infobox
QuetiapineChEMBLChEMBL716 Y1.00infobox
QuetiapineChemSpider4827 Y1.00infobox
QuetiapineCompTox Dashboard (EPA)DTXSID90235461.00infobox
QuetiapineDrug classAtypical antipsychotic1.00infobox
QuetiapineDrugBankDB01224 Y1.00infobox
QuetiapineECHA InfoCard100.131.1931.00infobox
QuetiapineElimination half-life7 hours (parent compound); 9–12 hours (active metabolite, norquetiapine)1.00infobox
QuetiapineExcretionKidney (73%), feces (20%)1.00infobox
QuetiapineFormulaC21H25N3O2S1.00infobox
QuetiapineIUPHAR/BPS501.00infobox
QuetiapineKEGGD08456 Y1.00infobox
QuetiapineLegal statusAU: S4 (Prescription only)1.00infobox
QuetiapineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
QuetiapineLegal statusCA: ℞-only1.00infobox
QuetiapineLegal statusNZ: Prescription only1.00infobox
QuetiapineLegal statusUK: POM (Prescription only)1.00infobox
QuetiapineLegal statusUS: ℞-only1.00infobox
QuetiapineLicense dataUS DailyMed: Quetiapine1.00infobox
QuetiapineMedlinePlusa6980191.00infobox
QuetiapineMetabolismLiver via CYP3A4-catalysed sulfoxidation to its active metabolite norquetiapine (N-desalkylquetiapine)1.00infobox
QuetiapineMolar mass383.51 g·mol−11.00infobox
QuetiapinePregnancy categoryAU: B31.00infobox
QuetiapinePronunciation/kwɪˈtaɪ.əpiːn/ kwi-TY-ə-peen1.00infobox
QuetiapineProtein binding83%1.00infobox

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