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Sepsis

Sepsis (also referred to as blood poisoning) is a potentially life-threatening condition that arises when the body's dysregulated response to infection causes injury to its own tissues and organs.

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Key facts & relationships

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Causes
Immune response triggered by an infection
Complications
Multiple organ dysfunction syndrome · temporary, transient, or permanent organ damage
Deaths
11 million (2017, WHO)
Diagnostic method
Sequential organ failure assessment (SOFA) score, Systemic inflammatory response syndrome (SIRS) criteria
Frequency
48.9 million cases (2017, WHO)
Prevention
Vaccination

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Overview

Signs and symptoms

Cause

Pathophysiology

Diagnosis

Treatment

Epidemiology

History

Society and culture

Research

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Map overview Semantic statistics

Sepsis

Nodes383
Edges382
Triples317
Avg. degree1.99
Density0.005222
Components1

How this topic connects Entity context

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Sepsis

Top relations

related to Microbial factors · 21
Sepsis → An, Bacterial, C-type, Consequently, CpG, DNA, Examples, Invariably, NOD-like, PAMP, PAMPs, PRR, PRRs, RIG-I-like, Several, Superantigens, T-cell, T-cells, There, These PAMPs
related to Antibiotics · 19
Sepsis → Acinetobacter, Antibiotic, Cultures, For, For Legionella, If, In, MRSA, Others, Prolonged, Pseudomonas, Several, SIRS, Some, Staphylococcus, The, These, Treatment, Two
related to Research · 18
Sepsis → Although, Bacteroides, Candida, Clostridium, Escherichia, Klebsiella, Lactobacillus, Not, Proteus, Pseudomonas, Rather, Recent, Some, Staphylococcus, Streptococcus, The, Under, What
related to Anesthesia · 17
Sepsis → Although, ARDS, CPAP, General, H2O, High, However, Inhalational, It, Minimizing, PBW, PEEP, Predicted, Recruitment, Requirements, The, Usually
related to history · 16
Sepsis → All, Avicenna, BC, Diseases, Hippocrates, Homer, ICD, ICD-10, In, Related Health Problems, Streptococcal, The, The Greek, The International Statistical Classification, Though, US
related to Cause · 15
Sepsis → After, But, Candida, Echinococcus, Escherichia, Fungal, Gram-positive, Infections, Klebsiella, Other, Plasmodium, Pseudomonas, Schistosoma, Streptococcus, The
related to Early goal-directed therapy · 13
Sepsis → An, ARISE, Early, EGDT, Following, However, In, It, ProCESS, ProMISe, ScvO2, Surviving Sepsis Campaign, The
related to Blood products · 12
Sepsis → Erythropoietin, Evidence, Fresh, However, IgM-enriched, In, IV, IVIG, Meanwhile, Monoclonal, On, The Surviving Sepsis Campaign
related to Intravenous fluids · 12
Sepsis → Albumin, ARDS, Balanced, Crystalloid, If, In, MAP, Once, ScvO2, Starches, The Surviving Sepsis Campaign, Various
related to Steroids · 12
Sepsis → ARDS, Cochrane, During, However, It, IV, Neither ACTH, Studies, Surviving Sepsis Campaign, The, This, Treatment

Important terminology Word statistics

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Important terminology

blood may severe also shock infection pressure people septic recommended antibiotics immune include however low bacteria system sirs use mortality

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
SepsisCausesImmune response triggered by an infection1.00infobox
SepsisComplicationsMultiple organ dysfunction syndrome1.00infobox
SepsisComplicationstemporary, transient, or permanent organ damage1.00infobox
SepsisDeaths11 million (2017, WHO)1.00infobox
SepsisDiagnostic methodSequential organ failure assessment (SOFA) score, Systemic inflammatory response syndrome (SIRS) criteria1.00infobox
SepsisFrequency48.9 million cases (2017, WHO)1.00infobox
SepsisPreventionVaccination1.00infobox
SepsisPrognosis~30% mortality rate; ~80% mortality rate in cases of septic shock1.00infobox
SepsisPronunciation/ˈsɛpsɪs/1.00infobox
SepsisRisk factorsYoung or old age1.00infobox
SepsisRisk factorscancer1.00infobox
SepsisRisk factorsdiabetes1.00infobox
SepsisRisk factorsmajor trauma1.00infobox
SepsisRisk factorsburns1.00infobox
SepsisSpecialtyInfectious disease, critical care medicine, emergency medicine1.00infobox
SepsisSymptomsFever1.00infobox
SepsisSymptomsincreased heart rate1.00infobox
SepsisSymptomslow blood pressure1.00infobox
SepsisSymptomsincreased breathing rate1.00infobox
SepsisSymptomslow or absent urine output1.00infobox
SepsisSymptomssevere pain1.00infobox
SepsisSymptomsconfusion1.00infobox
SepsisTreatmentIntravenous fluids, antimicrobials, vasopressors, blood filtration or dialysis1.00infobox
SepsisUsual onsetMay be rapid (less than three hours) or prolonged (several days)[citation needed]1.00infobox
Sepsisis ainfection by Candida species of yeast0.90text
Sepsisis aresult of various processes0.90text
Sepsisis ainfectious disease state associated with multiple organ dysfunction syndrome0.90text
Sepsisis asingle disease process has been challenged by findings of distinct immune phenotypes0.90text

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