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Protriptyline, sold under the brand name Vivactil among others, is a tricyclic antidepressant (TCA), specifically a secondary amine. Uniquely among most of the TCAs, protriptyline tends to be energizing instead of sedating, and is sometimes used for narcolepsy to achieve a wakefulness-promoting effect.
The analysis highlights History, Community, Culture and Applications as prominent areas in the source structure around Protriptyline.
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Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Protriptyline shows recurring relationship patterns in the source. For example, Protriptyline → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, DCITTooltip Denominazione Comune Italiana, English, French, German, INNTooltip International Nonproprietary Name, Italian, Latin, Name, Spanish, USANTooltip United States Adopted, USPTooltip United States Pharmacopeia Another extracted example is Protriptyline → C19H21N1, N-methylated, N-methylpropan-1-amine, TCA, TCAs, The CAS Registry Number. Use these groups to spot repeated connection types before inspecting the individual relationships.
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may tcas drug used side also overdose urinary effects tca depression patients mg especially name antidepressants retention include amine including
TTTA extracted 91 structured relationships around Protriptyline. Examples in this analysis include Protriptyline → 3D model (JSmol) → Interactive image and Protriptyline → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Protriptyline | 3D model (JSmol) | Interactive image | 1.00 | infobox |
| Protriptyline | AHFS/Drugs.com | Monograph | 1.00 | infobox |
| Protriptyline | ATC code | N06AA11 (WHO) | 1.00 | infobox |
| Protriptyline | Bioavailability | 77–93% | 1.00 | infobox |
| Protriptyline | CAS Number | 438-60-8 Y 1225-55-4 (hydrochloride) | 1.00 | infobox |
| Protriptyline | ChEBI | CHEBI:8597 Y | 1.00 | infobox |
| Protriptyline | ChEMBL | ChEMBL668 Y | 1.00 | infobox |
| Protriptyline | ChemSpider | 4805 Y | 1.00 | infobox |
| Protriptyline | CompTox Dashboard (EPA) | DTXSID0023535 | 1.00 | infobox |
| Protriptyline | DrugBank | DB00344 Y | 1.00 | infobox |
| Protriptyline | ECHA InfoCard | 100.006.474 | 1.00 | infobox |
| Protriptyline | Elimination half-life | 54–92 hours | 1.00 | infobox |
| Protriptyline | Excretion | Urine: 50% Feces: minor | 1.00 | infobox |
| Protriptyline | Formula | C19H21N | 1.00 | infobox |
| Protriptyline | IUPHAR/BPS | 7285 | 1.00 | infobox |
| Protriptyline | KEGG | D08447 | 1.00 | infobox |
| Protriptyline | Legal status | BR: Class C1 (Other controlled substances) | 1.00 | infobox |
| Protriptyline | Legal status | In general: ℞ (Prescription only) | 1.00 | infobox |
| Protriptyline | MedlinePlus | a604025 | 1.00 | infobox |
| Protriptyline | Metabolism | Hepatic | 1.00 | infobox |
| Protriptyline | Molar mass | 263.384 g·mol−1 | 1.00 | infobox |
| Protriptyline | Other names | Amimethyline; Protriptyline hydrochloride; MK-240 | 1.00 | infobox |
| Protriptyline | Protein binding | 92% | 1.00 | infobox |
| Protriptyline | PubChem CID | 4976 | 1.00 | infobox |
| Protriptyline | Routes of administration | Oral | 1.00 | infobox |
| Protriptyline | Trade names | Vivactyl, others | 1.00 | infobox |
| Protriptyline | UNII | 4NDU154T12 | 1.00 | infobox |
| Protriptyline | is a | right antidepressant for them | 0.90 | text |
| Protriptyline | is a | TCA | 0.90 | text |
| Protriptyline | is a | secondary amine TCA | 0.90 | text |
The concept neighborhoods around Protriptyline bring nearby vocabulary together. In this analysis, examples include Tcas, Used and Effects. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Protriptyline, one of the stronger structural bridges in this analysis connects Protriptyline with Side effects. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Protriptyline to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Community, Culture & Applications, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Protriptyline · EN edition · Analysis: TopicsToTalkAbout