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Butriptyline

Butriptyline, sold under the brand name Evadyne among others, is a tricyclic antidepressant (TCA) that has been used in the United Kingdom and several other European countries for the treatment of depression but appears to no longer be marketed. Along with trimipramine, iprindole, and amoxapine, it has been described as an "atypical" or…

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Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
N06AA15 (WHO)
Bioavailability
?
CAS Number
35941-65-2 Y · HCl: 5585-73-9 Y
ChEBI
CHEBI:135227 Y
ChEMBL
ChEMBL2110816 N

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Overview

Side effects

Pharmacology

Chemistry

History

Society and culture

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Map overview Semantic statistics

Butriptyline

Nodes85
Edges84
Triples71
Avg. degree1.98
Density0.023529
Components1

How this topic connects Entity context

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Butriptyline

Top relations

related to Generic names · 12
Butriptyline → BANMTooltip British Approved Name, BANTooltip British Approved Name, DCFTooltip Dénomination Commune Française, English, French, German, INNTooltip International Nonproprietary Name, Its, Latin, Name, Spanish, USANTooltip United States Adopted
related to Chemistry · 7
Butriptyline → C21H27N, It, Other, TCA, TCAs, The, The CAS Registry Number
related to Availability · 6
Butriptyline → Austria, Belgium, Europe, Italy, Luxembourg, United Kingdom
related to Pharmacodynamics · 6
Butriptyline → As, However, HT2, In, TCAs, These
related to Brand names · 4
Butriptyline → Centrolese, Evadene, Evadyne, Evasidol
has effect · 3
Butriptyline → It, TCAs, The
CAS Number · 2
Butriptyline → 35941-65-2 Y, HCl: 5585-73-9 Y
Legal status · 2
Butriptyline → BR: Class C1 (Other controlled substances), In general: ℞ (Prescription only)
UNII · 2
Butriptyline → HCl: LIJ2H8658W Y, Z22441975X
is a · 2
Butriptyline → analogue of amitriptyline with an isobutyl side chain instead of a propylidene side chain, strong antihistamine and anticholinergic

Important terminology Word statistics

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Important terminology

side effects name amitriptyline tcas used united tca trimipramine brand evadyne number names kingdom marketed hydrochloride pharmacology generic depression iprindole

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Butriptyline3D model (JSmol)Interactive image1.00infobox
ButriptylineATC codeN06AA15 (WHO)1.00infobox
ButriptylineBioavailability?1.00infobox
ButriptylineCAS Number35941-65-2 Y1.00infobox
ButriptylineCAS NumberHCl: 5585-73-9 Y1.00infobox
ButriptylineChEBICHEBI:135227 Y1.00infobox
ButriptylineChEMBLChEMBL2110816 N1.00infobox
ButriptylineChemSpider20462 Y1.00infobox
ButriptylineChiralityRacemic mixture1.00infobox
ButriptylineCompTox Dashboard (EPA)DTXSID60227151.00infobox
ButriptylineDrugBankDB09016 N1.00infobox
ButriptylineElimination half-life20 hours1.00infobox
ButriptylineFormulaC21H27N1.00infobox
ButriptylineKEGGD07601 Y1.00infobox
ButriptylineLegal statusBR: Class C1 (Other controlled substances)1.00infobox
ButriptylineLegal statusIn general: ℞ (Prescription only)1.00infobox
ButriptylineMetabolismHepatic (N-demethylation)1.00infobox
ButriptylineMetabolitesNorbutriptyline1.00infobox
ButriptylineMolar mass293.454 g·mol−11.00infobox
ButriptylineOther namesAY-620141.00infobox
ButriptylineProtein binding>90%1.00infobox
ButriptylinePubChem CID217721.00infobox
ButriptylineRoutes of administrationOral1.00infobox
ButriptylineTrade namesEvadyne, others1.00infobox
ButriptylineUNIIZ22441975X1.00infobox
ButriptylineUNIIHCl: LIJ2H8658W Y1.00infobox
Butriptylineis astrong antihistamine and anticholinergic0.90text
Butriptylineis aanalogue of amitriptyline with an isobutyl side chain instead of a propylidene side chain0.90text

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