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CARD11: Function, Structure & Interactions

Caspase recruitment domain-containing protein 11 also known as CARD-containing MAGUK protein 1 (Carma 1) is a protein in the CARD-CC protein family that in humans is encoded by the CARD11 gene. CARD 11 is a membrane associated protein that is found in various human tissues, including the thymus, spleen, liver, and peripheral blood leukocytes. Similarly…

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CARD11 topic overview

The analysis highlights Function, Structure and Interactions as prominent areas in the source structure around CARD11.

Related topics
21
Source areas
4
Connected nodes
25
Extracted relationships
135
Concept neighborhoods
16
Bridge connections
25

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 16 topics
Overview · 3 topics
Interactions · 1 topics
Structure · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, caspase recruitment domain family member 11, IMD11A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JUP, 4LWD
Band
7p22.2 · 5|5 G2
Bgee
granulocyte · lymph node · spleen · appendix · blood
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Structure

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How CARD11 connects Entity context

The extracted context around CARD11 shows recurring relationship patterns in the source. For example, CARD11 → B cell differentiation, B cell proliferation, CARD domain binding, CBM complex, cytoplasm, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, GDP metabolic process, GMP metabolic process, guanylate kinase activity, homeostasis of number of cells, I-kappaB kinase/NF-kappaB signaling, immunoglobulin production, immunological synapse, lymphocyte activation, membrane, membrane raft, plasma membrane, positive regulation of B cell proliferation Another extracted example is CARD11 → After, BCL10, CARD, CARD-CC, CARD10, CARD14, CARMA, CARMA1, CARMA2, CARMA3, Loss, MAGUK, MALT1, NF-κB, PKC-β, PKC-θ, SCID, The, The CARD, This. Use these groups to spot repeated connection types before inspecting the individual relationships.

CARD11

Top relations

Gene ontology · 38
CARD11 → B cell differentiation, B cell proliferation, CARD domain binding, CBM complex, cytoplasm, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, GDP metabolic process, GMP metabolic process, guanylate kinase activity, homeostasis of number of cells, I-kappaB kinase/NF-kappaB signaling, immunoglobulin production, immunological synapse, lymphocyte activation, membrane, membrane raft, plasma membrane, positive regulation of B cell proliferation
related to Function · 21
CARD11 → After, BCL10, CARD, CARD-CC, CARD10, CARD14, CARMA, CARMA1, CARMA2, CARMA3, Loss, MAGUK, MALT1, NF-κB, PKC-β, PKC-θ, SCID, The, The CARD, This
Bgee · 17
CARD11 → amniotic fluid, appendix, blood, ciliary body, duodenum, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, palpebral conjunctiva, Paneth cell, parotid gland, spleen, subcutaneous adipose tissue, superficial temporal artery, thymus
RNA expression pattern · 17
CARD11 → amniotic fluid, appendix, blood, ciliary body, duodenum, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, palpebral conjunctiva, Paneth cell, parotid gland, spleen, subcutaneous adipose tissue, superficial temporal artery, thymus
related to Structure · 12
CARD11 → BCL10, C-terminus, CARD, In, MAGUK, N-terminus, NF-κB, On, Protein, The, The CARD, This
related to Interactions · 4
CARD11 → BCL10, CARD, NF-κB, This
Band · 2
CARD11 → 5|5 G2, 7p22.2
Chr. · 2
CARD11 → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
CARD11 → 140,986,337 bp, 3,043,867 bp
related to External links · 2
CARD11 → Human CARD11, UCSC Genome Browser

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

card domain protein human bcl10 nf-κb bp gene family chr 11 band cells function chromosome membrane recruitment location maguk also

CARD11 relationships Subject–Predicate–Object triples

TTTA extracted 135 structured relationships around CARD11. Examples in this analysis include CARD11 → Aliases → CARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, caspase recruitment domain family member 11, IMD11A and CARD11 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JUP, 4LWD. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
CARD11AliasesCARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, caspase recruitment domain family member 11, IMD11A1.00infobox
CARD11Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JUP, 4LWD1.00infobox
CARD11Band7p22.21.00infobox
CARD11Band5|5 G21.00infobox
CARD11Bgeegranulocyte1.00infobox
CARD11Bgeelymph node1.00infobox
CARD11Bgeespleen1.00infobox
CARD11Bgeeappendix1.00infobox
CARD11Bgeeblood1.00infobox
CARD11Bgeesuperficial temporal artery1.00infobox
CARD11Bgeeparotid gland1.00infobox
CARD11Bgeepalpebral conjunctiva1.00infobox
CARD11Bgeeamniotic fluid1.00infobox
CARD11Bgeegallbladder1.00infobox
CARD11Bgeemesenteric lymph nodes1.00infobox
CARD11Bgeethymus1.00infobox
CARD11Bgeeciliary body1.00infobox
CARD11BgeePaneth cell1.00infobox
CARD11Bgeeembryo1.00infobox
CARD11Bgeesubcutaneous adipose tissue1.00infobox
CARD11Bgeeduodenum1.00infobox
CARD11BioGPSn/a1.00infobox
CARD11Chr.Chromosome 7 (human)1.00infobox
CARD11Chr.Chromosome 5 (mouse)1.00infobox
CARD11DatabasesNCBI: entry; OMA: entry1.00infobox
CARD11End3,043,867 bp1.00infobox
CARD11End140,986,337 bp1.00infobox
CARD11EnsemblENSG000001982861.00infobox
CARD11Entrez844331.00infobox
CARD11External IDsOMIM: 607210; MGI: 1916978; GeneCards: CARD111.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around CARD11 bring nearby vocabulary together. In this analysis, examples include Domain, Bcl10 and Maguk. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • CARD11
    • Domain
    • Bcl10
    • Maguk
    • Function
    • Gene
    • Family
    • Nf-κb
    • Cell
    • Receptor
    • Structure
    • Card
    • Activity
  • card11
    • Domain
    • Bcl10
    • Maguk
    • Function
    • Gene
    • Family
    • Nf-κb
    • Cell
    • Receptor
    • Structure
    • Card
    • Activity
  • protein
    • Family
    • Recruitment
    • Card
    • Blood
    • Kinase
    • Spleen
    • Thymus
    • Activation
    • Domain
    • Membrane
    • Proteins
    • Maguk
  • card-cc protein family
    • Recruitment
    • Family
    • Protein
    • Proteins
    • Member
    • Maguk
    • Domain
    • Function
    • Gene
    • Card
    • Blood
    • Kinase
  • gene
    • Location
    • Human
    • Chromosome
    • Bp
    • Chr
    • Mouse
    • Band
    • Maguk
    • Recruitment
    • Function
    • External
    • Protein
  • card
    • Domain
    • Signaling
    • Nf-κb
    • Protein
    • Activation
    • Activity
    • Bcl10
    • Family
    • Blood
    • Found
    • Spleen
    • Thymus
  • protein kinase c
    • Family
    • Recruitment
    • Mouse
    • Spleen
    • Thymus
    • Card
    • Blood
    • Kinase
    • Protein
    • Activation
    • Domain
    • Membrane
  • function
    • Activation
    • Cell
    • Proteins
    • Receptor
    • Chromosome
    • Location
    • Recruitment
    • Bp
    • Chr
    • Gene
    • Human
    • Domain

Connections between topic areas Semantic bridges

For CARD11, one of the stronger structural bridges in this analysis connects CARD11 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
CARD11Function · splits 9 ⟂ 17
CARD11Overview · splits 22 ⟂ 4

Map overview Semantic statistics

CARD11

Nodes26
Edges25
Triples135
Avg. degree1.92
Density0.076923
Components1

Source & methodology

TTTA analyzes the structure around CARD11 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Structure & Interactions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — CARD11 · EN edition · Analysis: TopicsToTalkAbout

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