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CARD11

Caspase recruitment domain-containing protein 11 also known as CARD-containing MAGUK protein 1 (Carma 1) is a protein in the CARD-CC protein family that in humans is encoded by the CARD11 gene. CARD 11 is a membrane associated protein that is found in various human tissues, including the thymus, spleen, liver, and peripheral blood leukocytes. Similarly…

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Function

16 related topics

Structure

1 related topics

Interactions

1 related topics

Overview

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Key facts & relationships

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Aliases
CARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, caspase recruitment domain family member 11, IMD11A
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JUP, 4LWD
Band
7p22.2 · 5|5 G2
Bgee
granulocyte · lymph node · spleen · appendix · blood
BioGPS
n/a
Chr.
Chromosome 7 (human) · Chromosome 5 (mouse)

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Overview

Function

Structure

Interactions

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Map overview Semantic statistics

CARD11

Nodes26
Edges25
Triples135
Avg. degree1.92
Density0.076923
Components1

How this topic connects Entity context

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CARD11

Top relations

Gene ontology · 38
CARD11 → B cell differentiation, B cell proliferation, CARD domain binding, CBM complex, cytoplasm, cytosol, extracellular exosome, Fc-epsilon receptor signaling pathway, GDP metabolic process, GMP metabolic process, guanylate kinase activity, homeostasis of number of cells, I-kappaB kinase/NF-kappaB signaling, immunoglobulin production, immunological synapse, lymphocyte activation, membrane, membrane raft, plasma membrane, positive regulation of B cell proliferation
related to Function · 21
CARD11 → After, BCL10, CARD, CARD-CC, CARD10, CARD14, CARMA, CARMA1, CARMA2, CARMA3, Loss, MAGUK, MALT1, NF-κB, PKC-β, PKC-θ, SCID, The, The CARD, This
Bgee · 17
CARD11 → amniotic fluid, appendix, blood, ciliary body, duodenum, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, palpebral conjunctiva, Paneth cell, parotid gland, spleen, subcutaneous adipose tissue, superficial temporal artery, thymus
RNA expression pattern · 17
CARD11 → amniotic fluid, appendix, blood, ciliary body, duodenum, embryo, gallbladder, granulocyte, lymph node, mesenteric lymph nodes, palpebral conjunctiva, Paneth cell, parotid gland, spleen, subcutaneous adipose tissue, superficial temporal artery, thymus
related to Structure · 12
CARD11 → BCL10, C-terminus, CARD, In, MAGUK, N-terminus, NF-κB, On, Protein, The, The CARD, This
related to Interactions · 4
CARD11 → BCL10, CARD, NF-κB, This
Band · 2
CARD11 → 5|5 G2, 7p22.2
Chr. · 2
CARD11 → Chromosome 5 (mouse), Chromosome 7 (human)
End · 2
CARD11 → 140,986,337 bp, 3,043,867 bp
related to External links · 2
CARD11 → Human CARD11, UCSC Genome Browser

Important terminology Word statistics

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Important terminology

card domain protein human bcl10 nf-κb bp gene family chr 11 band cells function chromosome membrane recruitment location maguk also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CARD11AliasesCARD11, BENTA, BIMP3, CARMA1, IMD11, PPBL, caspase recruitment domain family member 11, IMD11A1.00infobox
CARD11Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4JUP, 4LWD1.00infobox
CARD11Band7p22.21.00infobox
CARD11Band5|5 G21.00infobox
CARD11Bgeegranulocyte1.00infobox
CARD11Bgeelymph node1.00infobox
CARD11Bgeespleen1.00infobox
CARD11Bgeeappendix1.00infobox
CARD11Bgeeblood1.00infobox
CARD11Bgeesuperficial temporal artery1.00infobox
CARD11Bgeeparotid gland1.00infobox
CARD11Bgeepalpebral conjunctiva1.00infobox
CARD11Bgeeamniotic fluid1.00infobox
CARD11Bgeegallbladder1.00infobox
CARD11Bgeemesenteric lymph nodes1.00infobox
CARD11Bgeethymus1.00infobox
CARD11Bgeeciliary body1.00infobox
CARD11BgeePaneth cell1.00infobox
CARD11Bgeeembryo1.00infobox
CARD11Bgeesubcutaneous adipose tissue1.00infobox
CARD11Bgeeduodenum1.00infobox
CARD11BioGPSn/a1.00infobox
CARD11Chr.Chromosome 7 (human)1.00infobox
CARD11Chr.Chromosome 5 (mouse)1.00infobox
CARD11DatabasesNCBI: entry; OMA: entry1.00infobox
CARD11End3,043,867 bp1.00infobox
CARD11End140,986,337 bp1.00infobox
CARD11EnsemblENSG000001982861.00infobox
CARD11Entrez844331.00infobox
CARD11External IDsOMIM: 607210; MGI: 1916978; GeneCards: CARD111.00infobox

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