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MALT1

Mucosa-associated lymphoid tissue lymphoma translocation protein 1 is a protein that in humans is encoded by the MALT1 gene. It is the human paracaspase.

Function, Protease inhibitors & Interactions

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Function

23 related topics

Protease inhibitors

24 related topics

Interactions

3 related topics

Protease substrates

3 related topics

Key facts & relationships

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Aliases
MALT1, IMD12, MLT, MLT1, PCASP1, MALT1 paracaspase
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G7R, 3BFO, 3K0W, 3UO8, 3UOA, 3V4O, 3V55, 4I1P, 4I1R
Band
18q21.32 · 18|18 E1
Bgee
epithelium of colon · tonsil · testicle · Achilles tendon · monocyte
BioGPS
More reference expression data
Chr.
Chromosome 18 (human) · Chromosome 18 (mouse)

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Overview

Function

Interactions

Protease substrates

Protease inhibitors

Advanced semantic analysis

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Map overview Semantic statistics

MALT1

Nodes62
Edges61
Triples143
Avg. degree1.97
Density0.032258
Components1

How this topic connects Entity context

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MALT1

Top relations

Gene ontology · 42
MALT1 → activation of NF-kappaB-inducing kinase activity, B cell activation, B-1 B cell differentiation, CBM complex, cysteine-type endopeptidase activity, cytoplasm, cytosol, defense response, Fc-epsilon receptor signaling pathway, fibrillar center, hydrolase activity, identical protein binding, innate immune response, kinase activator activity, negative regulation of apoptotic process, nuclear export, nucleolus, nucleus, peptidase activity, perinuclear region of cytoplasm
related to Protease inhibitors · 30
MALT1 → AbbVie, ACS, Analogs, AstraZeneca, Biperiden, CD3, Centre, Chordia, Dictyosporium, Discovery, Drug Design, First Time Disclosure Session, Initially, Janssen Pharmaceutica, Lapachone, Leuven-based, Lupin, LVSR, MI-2, Novartis
Bgee · 20
MALT1 → Achilles tendon, appendix, blood, buccal mucosa cell, epithelium of colon, genital tubercle, gonad, granulocyte, interventricular septum, lymph node, mesenteric lymph nodes, monocyte, muscle of thigh, neural layer of retina, spleen, stromal cell of endometrium, subcutaneous adipose tissue, tail of embryo, testicle, tonsil
RNA expression pattern · 20
MALT1 → Achilles tendon, appendix, blood, buccal mucosa cell, epithelium of colon, genital tubercle, gonad, granulocyte, interventricular septum, lymph node, mesenteric lymph nodes, monocyte, muscle of thigh, neural layer of retina, spleen, stromal cell of endometrium, subcutaneous adipose tissue, tail of embryo, testicle, tonsil
related to Protease substrates · 5
MALT1 → Currently, IAP2-MALT1, PCASP1, Since, Specifically
related to Interactions · 3
MALT1 → BCL10, SQSTM1/p62, TRAF6
Band · 2
MALT1 → 18q21.32, 18|18 E1
Chr. · 2
MALT1 → Chromosome 18 (human), Chromosome 18 (mouse)
End · 2
MALT1 → 58,754,477 bp, 65,612,138 bp
Aliases · 1
MALT1 → MALT1, IMD12, MLT, MLT1, PCASP1, MALT1 paracaspase

Important terminology Word statistics

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Important terminology

paracaspase protease activity inhibitors human bp gene nf-κb protein activation chr band substrates bcl10 shown inhibitor chromosome 18 mouse lymphocytes

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
MALT1AliasesMALT1, IMD12, MLT, MLT1, PCASP1, MALT1 paracaspase1.00infobox
MALT1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2G7R, 3BFO, 3K0W, 3UO8, 3UOA, 3V4O, 3V55, 4I1P, 4I1R1.00infobox
MALT1Band18q21.321.00infobox
MALT1Band18|18 E11.00infobox
MALT1Bgeeepithelium of colon1.00infobox
MALT1Bgeetonsil1.00infobox
MALT1Bgeetesticle1.00infobox
MALT1BgeeAchilles tendon1.00infobox
MALT1Bgeemonocyte1.00infobox
MALT1Bgeegonad1.00infobox
MALT1Bgeelymph node1.00infobox
MALT1Bgeebuccal mucosa cell1.00infobox
MALT1Bgeeappendix1.00infobox
MALT1Bgeestromal cell of endometrium1.00infobox
MALT1Bgeespleen1.00infobox
MALT1Bgeemesenteric lymph nodes1.00infobox
MALT1Bgeegranulocyte1.00infobox
MALT1Bgeetail of embryo1.00infobox
MALT1Bgeeblood1.00infobox
MALT1Bgeesubcutaneous adipose tissue1.00infobox
MALT1Bgeegenital tubercle1.00infobox
MALT1Bgeeneural layer of retina1.00infobox
MALT1Bgeeinterventricular septum1.00infobox
MALT1Bgeemuscle of thigh1.00infobox
MALT1BioGPSMore reference expression data1.00infobox
MALT1Chr.Chromosome 18 (human)1.00infobox
MALT1Chr.Chromosome 18 (mouse)1.00infobox
MALT1DatabasesNCBI: entry; OMA: entry1.00infobox
MALT1End58,754,477 bp1.00infobox
MALT1End65,612,138 bp1.00infobox

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