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CYP3A

Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene locus. A homologous locus is found in mice. These genes encode monooxygenases which catalyze many reactions involved in the synthesis of cholesterol, steroids and other lipids as well as drug metabolism.

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Key facts & relationships

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AlphaFold
IPR001128 · PF00067
Available protein structures:
IPR001128 · PF00067
CDD
cd00302
InterPro
IPR001128
Membranome
265
OPM protein
2bdm

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Map overview Semantic statistics

CYP3A

Nodes41
Edges40
Triples34
Avg. degree1.95
Density0.04878
Components1

How this topic connects Entity context

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CYP3A

Top relations

related to Endogenous substrate catabolism · 8
CYP3A → CYP3A4, CYP3A5, CYP3A7, EETs, For, The CYP3A, These, Variations
related to Structure · 6
CYP3A → Another, CYP450, NADPH, P450, Structurally, The
related to Xenobiotic metabolism · 6
CYP3A → Among, CYP3A-mediated, CYP3A4, Expression, The CYP3A, These
AlphaFold · 2
CYP3A → IPR001128, PF00067
Available protein structures: · 2
CYP3A → IPR001128, PF00067
CDD · 1
CYP3A → cd00302
InterPro · 1
CYP3A → IPR001128
Membranome · 1
CYP3A → 265
OPM protein · 1
CYP3A → 2bdm
OPM superfamily · 1
CYP3A → 39

Important terminology Word statistics

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Important terminology

metabolism enzymes cyp3a4 p450 subfamily locus drug also genes including involved cytochrome known well four region endogenous cholesterol lipids superfamily

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CYP3AAlphaFoldIPR0011281.00infobox
CYP3AAlphaFoldPF000671.00infobox
CYP3AAvailable protein structures:IPR0011281.00infobox
CYP3AAvailable protein structures:PF000671.00infobox
CYP3ACDDcd003021.00infobox
CYP3AInterProIPR0011281.00infobox
CYP3AMembranome2651.00infobox
CYP3AOPM protein2bdm1.00infobox
CYP3AOPM superfamily391.00infobox
CYP3APDBIPR001128 PF00067 (ECOD; PDBsum)1.00infobox
CYP3APfamPF000671.00infobox
CYP3APROSITEPDOC000811.00infobox
CYP3ASCOP22cpp / SCOPe / SUPFAM1.00infobox
CYP3ASymbolp4501.00infobox

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