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Nuclear receptor co-repressor 2

The nuclear receptor co-repressor 2 (NCOR2) is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains. In addition, NCOR2 appears to recruit histone deacetylases to DNA promoter regions. Hence NCOR2 assists nuclear receptors in the down regulation of target gene expression. NCOR2 is also referred to as a…

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28 related topics

Function

3 related topics

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Aliases
NCOR2, CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1, nuclear receptor corepressor 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RT5, 4OAR, 2L5G, 2LTP, 1KKQ, 3R2A, 2ODD, 4A69, 3R29, 1XC5, 1R2B,%%s1KKQ, 1R2B, 1XC5, 2GPV, 2LTP, 3R29, 3R2…
Band
12q24.31 · 5|5 G1.1
Bgee
sural nerve · anterior pituitary · canal of the cervix · parotid gland · right ovary
BioGPS
More reference expression data
Chr.
Chromosome 12 (human) · Chromosome 5 (mouse)

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Nuclear receptor co-repressor 2

Nodes43
Edges42
Triples97
Avg. degree1.95
Density0.046512
Components1

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Nuclear receptor co-repressor 2

Top relations

Gene ontology · 34
Nuclear receptor co-repressor 2 → chromatin, chromatin binding, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, estrous cycle, glucocorticoid receptor binding, histone deacetylase binding, histone deacetylase complex, lactation, membrane, negative regulation of androgen receptor signaling pathway, negative regulation of production of miRNAs involved in gene silencing by miRNA, negative regulation of transcription by RNA polymerase II, negative regulation of transcription, DNA-templated, Notch binding, nuclear body, nuclear matrix, nuclear receptor binding, nucleoplasm, nucleus
Bgee · 19
Nuclear receptor co-repressor 2 → anterior pituitary, body of uterus, CA3 field, canal of the cervix, dentate gyrus of hippocampal formation granule cell, genital tubercle, left ovary, left uterine tube, lip, muscle of thigh, parotid gland, perirhinal cortex, primary visual cortex, right hemisphere of cerebellum, right ovary, Rostral migratory stream, superior frontal gyrus, sural nerve, ventricular zone
RNA expression pattern · 19
Nuclear receptor co-repressor 2 → anterior pituitary, body of uterus, CA3 field, canal of the cervix, dentate gyrus of hippocampal formation granule cell, genital tubercle, left ovary, left uterine tube, lip, muscle of thigh, parotid gland, perirhinal cortex, primary visual cortex, right hemisphere of cerebellum, right ovary, Rostral migratory stream, superior frontal gyrus, sural nerve, ventricular zone
Band · 2
Nuclear receptor co-repressor 2 → 12q24.31, 5|5 G1.1
Chr. · 2
Nuclear receptor co-repressor 2 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
Nuclear receptor co-repressor 2 → 124,567,589 bp, 125,179,219 bp
related to Interactions · 2
Nuclear receptor co-repressor 2 → ARBCL6C-FosC-junHDAC1HDAC3HDAC4HDAC5HDAC10MeCP2NR4A1POU2F1PPARDPGRPMLRBPJRELARUNX1T1RARASIN3ASNW1SPENSRFTBL1XTHRBVDRZBTB16, Nuclear
Aliases · 1
Nuclear receptor co-repressor 2 → NCOR2, CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1, nuclear receptor corepressor 2
Available structures · 1
Nuclear receptor co-repressor 2 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RT5, 4OAR, 2L5G, 2LTP, 1KKQ, 3R2A, 2ODD, 4A69, 3R29, 1XC5, 1R2B,%%s1KKQ, 1R2B, 1XC5, 2GPV, 2LTP, 3R29, 3R2…
BioGPS · 1
Nuclear receptor co-repressor 2 → More reference expression data

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Important terminology

ncor2 nuclear bp human smrt chr band receptor protein gene chromosome 12 corepressor histone dna trac-1 location co-repressor coregulatory receptors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nuclear receptor co-repressor 2AliasesNCOR2, CTG26, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1, nuclear receptor corepressor 21.00infobox
Nuclear receptor co-repressor 2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RT5, 4OAR, 2L5G, 2LTP, 1KKQ, 3R2A, 2ODD, 4A69, 3R29, 1XC5, 1R2B,%%s1KKQ, 1R2B, 1XC5, 2GPV, 2LTP, 3R29, 3R2…1.00infobox
Nuclear receptor co-repressor 2Band12q24.311.00infobox
Nuclear receptor co-repressor 2Band5|5 G1.11.00infobox
Nuclear receptor co-repressor 2Bgeesural nerve1.00infobox
Nuclear receptor co-repressor 2Bgeeanterior pituitary1.00infobox
Nuclear receptor co-repressor 2Bgeecanal of the cervix1.00infobox
Nuclear receptor co-repressor 2Bgeeparotid gland1.00infobox
Nuclear receptor co-repressor 2Bgeeright ovary1.00infobox
Nuclear receptor co-repressor 2Bgeeleft ovary1.00infobox
Nuclear receptor co-repressor 2Bgeeleft uterine tube1.00infobox
Nuclear receptor co-repressor 2Bgeebody of uterus1.00infobox
Nuclear receptor co-repressor 2Bgeemuscle of thigh1.00infobox
Nuclear receptor co-repressor 2Bgeeright hemisphere of cerebellum1.00infobox
Nuclear receptor co-repressor 2Bgeesuperior frontal gyrus1.00infobox
Nuclear receptor co-repressor 2Bgeeprimary visual cortex1.00infobox
Nuclear receptor co-repressor 2Bgeelip1.00infobox
Nuclear receptor co-repressor 2BgeeRostral migratory stream1.00infobox
Nuclear receptor co-repressor 2BgeeCA3 field1.00infobox
Nuclear receptor co-repressor 2Bgeeventricular zone1.00infobox
Nuclear receptor co-repressor 2Bgeegenital tubercle1.00infobox
Nuclear receptor co-repressor 2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
Nuclear receptor co-repressor 2Bgeeperirhinal cortex1.00infobox
Nuclear receptor co-repressor 2BioGPSMore reference expression data1.00infobox
Nuclear receptor co-repressor 2Chr.Chromosome 12 (human)1.00infobox
Nuclear receptor co-repressor 2Chr.Chromosome 5 (mouse)1.00infobox
Nuclear receptor co-repressor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Nuclear receptor co-repressor 2End124,567,589 bp1.00infobox
Nuclear receptor co-repressor 2End125,179,219 bp1.00infobox
Nuclear receptor co-repressor 2EnsemblENSG000001964981.00infobox

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