Frizzled

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Frizzled topic overview

The analysis highlights Members, Group members and Function as prominent areas in the source structure around Frizzled.

Related topics: 26
Source areas: 5
Connected nodes: 31
Extracted relationships: 69
Concept neighborhoods: 15
Bridge connections: 31

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Group members · 10 topics

Function · 6 topics

Overview · 4 topics

As a drug target · 3 topics

Structure · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold: IPR000539 · PF01534
Available protein structures:: IPR000539 · PF01534
CDD: cd13951
InterPro: IPR000539
OPM protein: 4jkv
OPM superfamily: 6

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

G protein-coupled receptors G protein-coupled receptor
Wnt signaling pathway
Dishevelled
Cytosol

Structure

Transmembrane proteins Transmembrane protein
Cell membrane
Receptor tyrosine kinases

Function

Group members

As a drug target

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Frizzled connects Entity context

The extracted context around Frizzled shows recurring relationship patterns in the source. For example, Frizzled → Frizzled-1, Frizzled-10, Frizzled-2, Frizzled-3, Frizzled-4, Frizzled-5, Frizzled-6, Frizzled-7, Frizzled-8, Frizzled-9, FZD1, FZD10, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9 Another extracted example is Frizzled → Archived, Basic, Clinical Pharmacology, Frizzled Receptors, International Union, Ion Channels, IUPHAR Database, Medicine Medical Subject Headings, MeSH, National Library, Receptors, Retrieved. Use these groups to spot repeated connection types before inspecting the individual relationships.

Top relations

related to Group members · 21

Frizzled → Frizzled-1, Frizzled-10, Frizzled-2, Frizzled-3, Frizzled-4, Frizzled-5, Frizzled-6, Frizzled-7, Frizzled-8, Frizzled-9, FZD1, FZD10, FZD2, FZD3, FZD4, FZD5, FZD6, FZD7, FZD8, FZD9

related to External links · 12

Frizzled → Archived, Basic, Clinical Pharmacology, Frizzled Receptors, International Union, Ion Channels, IUPHAR Database, Medicine Medical Subject Headings, MeSH, National Library, Receptors, Retrieved

related to Function · 8

Frizzled → In, Mutations, PCP, These, Wingless-Int, Wnt, Wnt/calcium, Wnt/β-catenin

related to Structure · 6

Frizzled → All Frizzled, CRD, Dishevelled, Intracellularly, PDZ, The

related to The cysteine-rich domain · 5

Frizzled → MuSK, NSK2, ROR1, ROR2, The

AlphaFold · 2

Frizzled → IPR000539, PF01534

Available protein structures: · 2

Frizzled → IPR000539, PF01534

CDD · 1

Frizzled → cd13951

InterPro · 1

Frizzled → IPR000539

OPM protein · 1

Frizzled → 4jkv

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptors family protein domain members structure fz receptor transmembrane proteins polarity wnt signaling pathway pathways known cysteine-rich human dishevelled cell

Frizzled relationships Subject–Predicate–Object triples

TTTA extracted 69 structured relationships around Frizzled. Examples in this analysis include Frizzled → AlphaFold → IPR000539 and Frizzled → AlphaFold → PF01534. The table shows each extracted connection, where it came from and its confidence.

Subject	Predicate	Object	Confidence	Src
Frizzled	AlphaFold	IPR000539	1.00	infobox
Frizzled	AlphaFold	PF01534	1.00	infobox
Frizzled	Available protein structures:	IPR000539	1.00	infobox
Frizzled	Available protein structures:	PF01534	1.00	infobox
Frizzled	CDD	cd13951	1.00	infobox
Frizzled	InterPro	IPR000539	1.00	infobox
Frizzled	OPM protein	4jkv	1.00	infobox
Frizzled	OPM superfamily	6	1.00	infobox
Frizzled	PDB	IPR000539 PF01534 (ECOD; PDBsum)	1.00	infobox
Frizzled	Pfam	PF01534	1.00	infobox
Frizzled	Pfam clan	GPCR_A	1.00	infobox
Frizzled	PROSITE	PDOC50038	1.00	infobox
Frizzled	Symbol	Frizzled	1.00	infobox
Frizzled	TCDB	9.A.14	1.00	infobox
Frizzled	is a	family of atypical G protein-coupled receptors that serve as receptors in the Wnt signaling pathway and other signaling pathways	0.90	text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Frizzled bring nearby vocabulary together. In this analysis, examples include Receptors, Members and Proteins. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

Frizzled
- Receptors
- Members
- Proteins
- Domain
- Cysteine-rich
- Receptor
- Transmembrane
- Protein
- Activation
- Array
- Binding
- Called
frizzled
- Receptors
- Members
- Proteins
- Domain
- Cysteine-rich
- Receptor
- Transmembrane
- Protein
- Activation
- Array
- Binding
- Called
g protein-coupled receptors
- Binding
- Called
- Dishevelled
- Inside
- Tip
- Domain
- Cysteine-rich
- Domains
- Extracellular
- Membrane
- Pathway
- Pathways
transmembrane proteins
- Membrane
- Members
- Family
- Protein
- Cysteine-rich
- Domains
- Structure
- Domain
- Atypical
- Binding
- Called
- Dishevelled
cell membrane
- Transmembrane
- Domains
- Polarity
- Proteins
- Protein
- Binding
- Called
- Inside
- Protein-coupled
- Tip
- Extracellular
- Known
group members
- Transmembrane
- Cysteine-rich
- Membrane
- Structure
- Receptor
- Domain
- Protein
- Binding
- Called
- Dishevelled
- Function
- Inside
dishevelled
- Cytosol
- Binding
- Called
- Inside
- Protein-coupled
- Tip
- Cysteine-rich
- Domains
- Extracellular
- Membrane
- Structure
- Members
wnt signaling pathway
- Pathway
- Pathways
- Signaling
- Wnt
- Activation
- Atypical
- Binding
- Called
- Protein-coupled
- Cell
- Extracellular
- Known

Connections between topic areas Semantic bridges

For Frizzled, one of the stronger structural bridges in this analysis connects Frizzled with Group members. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Frizzled — Group members · splits 21 ⟂ 11

Frizzled — Function · splits 25 ⟂ 7

Frizzled — Overview · splits 27 ⟂ 5

Frizzled — Structure · splits 28 ⟂ 4

Frizzled — As a drug target · splits 28 ⟂ 4

Map overview Semantic statistics

Frizzled

Nodes32

Edges31

Triples69

Avg. degree1.94

Density0.0625

Components1

Source & methodology

TTTA analyzes the structure around Frizzled to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Members, Group members & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Frizzled · EN edition · Analysis: TopicsToTalkAbout