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Osteocyte

An osteocyte, an oblate-shaped type of bone cell with dendritic processes, is the most commonly found cell in mature bone. It can live as long as the organism itself. The adult human body has about 42 billion of them. Osteocytes do not divide and have an average half life of 25 years. They are derived from osteoprogenitor cells, some of which…

Clinical significance, Function & Development

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Key facts & relationships

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Location
Bone
FMA
66779
Latin
Osteocytus
MeSH
D010011
TH
H2.00.03.7.00003

Topics to explore

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Overview

Development

Function

Clinical significance

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Map overview Semantic statistics

Osteocyte

Nodes38
Edges37
Triples65
Avg. degree1.95
Density0.052632
Components1

How this topic connects Entity context

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Osteocyte

Top relations

related to Development · 14
Osteocyte → Although, DMP-1, During, E11, Examples, Klotho, LPA, MMPs, OF45, TGF-beta, The, Those, TIEG, Various
related to Clinical significance · 12
Osteocyte → Apoptotic, CD34, Clinically, M-CSF, Mechanical, Microdamage, Osteocytes, RANKL, Skeletal, TGF-β, The, Under
related to Sclerostin · 8
Osteocyte → BMP, LRP5/LRP6, Only, Osteocytes, PTH, Sclerostin, SOST, Wnt
related to Function · 5
Osteocyte → Although, Most, Osteocytes, They, When
related to Pathophysiology · 5
Osteocyte → Bone, Capillary, Nouveau, ON, Osteonecrosis
related to Structure · 3
Osteocyte → Golgi, Osteocytes, The
FMA · 1
Osteocyte → 66779
Latin · 1
Osteocyte → Osteocytus
Location · 1
Osteocyte → Bone
MeSH · 1
Osteocyte → D010011

Important terminology Word statistics

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Important terminology

osteocytes bone osteoblasts cell processes matrix sclerostin osteoclasts formation resorption cells mature called osteoblast apoptosis canaliculi hypoxia shown oxygen type

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
OsteocyteFMA667791.00infobox
OsteocyteLatinOsteocytus1.00infobox
OsteocyteLocationBone1.00infobox
OsteocyteMeSHD0100111.00infobox
OsteocyteTHH2.00.03.7.000031.00infobox
phosphatesinstance ofOsteocytes generate an inhibitory signal that is passed through their cell processes to osteoblasts for recruitment to enable bone formation.Osteocytes are also a key endocrine…0.80text
sclerostin have been shown to function in mineral metabolisminstance ofOsteocyte-specific proteins0.80text
as well as other molecules such as PHEXinstance ofOsteocyte-specific proteins0.80text
DMP-1instance ofOsteocyte-specific proteins0.80text
MEPEinstance ofOsteocyte-specific proteins0.80text
and FGF-23instance ofOsteocyte-specific proteins0.80text
which are highly expressed by osteocytesinstance ofOsteocyte-specific proteins0.80text

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    Min side: 3
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