Research any topic before you write.
Find related topics. | Discover entities. | See connections. | Build a topical map.
Integrin alpha M (ITGAM) is one protein subunit that forms heterodimeric integrin alpha-M beta-2 (αMβ2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A and cluster of differentiation molecule 11B (CD11B). The second chain of αMβ2 is the common integrin β2 subunit known as CD18, and integrin…
The analysis highlights Measurement, Function and Therapeutic significance as prominent areas in the source structure around Integrin alpha M.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around Integrin alpha M shows recurring relationship patterns in the source. For example, Integrin alpha M → amyloid-beta binding, amyloid-beta clearance, apoptotic signaling pathway, cargo receptor activity, cell adhesion, cell surface, cell surface receptor signaling pathway involved in cell-cell signaling, cell-cell adhesion via plasma-membrane adhesion molecules, complement component C3b binding, complement-mediated synapse pruning, cytokine-mediated signaling pathway, ectodermal cell differentiation, external side of plasma membrane, extracellular exosome, extracellular matrix organization, extracellular space, forebrain development, heat shock protein binding, immune system process, innate immune response Another extracted example is Integrin alpha M → appendix, blood, bone marrow, bone marrow cell, decidua, dentate gyrus of hippocampal formation granule cell, esophagus, granulocyte, hippocampus proper, ileum, jejunum, monocyte, spleen, striatum of neuraxis, trabecular bone, upper lobe of left lung, uterus. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cd11b itgam integrin also immune cytokines adhesion bp lupus migration involved human αmβ2 cell activation leukocyte leukocytes chr subunit complement
TTTA extracted 110 structured relationships around Integrin alpha M. Examples in this analysis include Integrin alpha M → Aliases → ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M and Integrin alpha M → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHO, 1BHQ, 1IDN, 1IDO, 1JLM, 1M1U, 1MF7, 1N9Z, 1NA5, 2LKE, 2LKJ, 3Q3G, 3QA3, 4M76, 4XW2. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Integrin alpha M | Aliases | ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M | 1.00 | infobox |
| Integrin alpha M | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHO, 1BHQ, 1IDN, 1IDO, 1JLM, 1M1U, 1MF7, 1N9Z, 1NA5, 2LKE, 2LKJ, 3Q3G, 3QA3, 4M76, 4XW2 | 1.00 | infobox |
| Integrin alpha M | Band | 16p11.2 | 1.00 | infobox |
| Integrin alpha M | Band | 7|7 F3 | 1.00 | infobox |
| Integrin alpha M | Bgee | monocyte | 1.00 | infobox |
| Integrin alpha M | Bgee | granulocyte | 1.00 | infobox |
| Integrin alpha M | Bgee | trabecular bone | 1.00 | infobox |
| Integrin alpha M | Bgee | bone marrow | 1.00 | infobox |
| Integrin alpha M | Bgee | blood | 1.00 | infobox |
| Integrin alpha M | Bgee | bone marrow cell | 1.00 | infobox |
| Integrin alpha M | Bgee | spleen | 1.00 | infobox |
| Integrin alpha M | Bgee | appendix | 1.00 | infobox |
| Integrin alpha M | Bgee | upper lobe of left lung | 1.00 | infobox |
| Integrin alpha M | Bgee | decidua | 1.00 | infobox |
| Integrin alpha M | Bgee | ileum | 1.00 | infobox |
| Integrin alpha M | Bgee | jejunum | 1.00 | infobox |
| Integrin alpha M | Bgee | dentate gyrus of hippocampal formation granule cell | 1.00 | infobox |
| Integrin alpha M | Bgee | hippocampus proper | 1.00 | infobox |
| Integrin alpha M | Bgee | esophagus | 1.00 | infobox |
| Integrin alpha M | Bgee | striatum of neuraxis | 1.00 | infobox |
| Integrin alpha M | Bgee | uterus | 1.00 | infobox |
| Integrin alpha M | BioGPS | More reference expression data | 1.00 | infobox |
| Integrin alpha M | Chr. | Chromosome 16 (human) | 1.00 | infobox |
| Integrin alpha M | Chr. | Chromosome 7 (mouse) | 1.00 | infobox |
| Integrin alpha M | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Integrin alpha M | End | 31,332,892 bp | 1.00 | infobox |
| Integrin alpha M | End | 127,717,663 bp | 1.00 | infobox |
| Integrin alpha M | Ensembl | ENSG00000169896 | 1.00 | infobox |
| Integrin alpha M | Entrez | 3684 | 1.00 | infobox |
| Integrin alpha M | External IDs | OMIM: 120980; MGI: 96607; GeneCards: ITGAM | 1.00 | infobox |
The concept neighborhoods around Integrin alpha M bring nearby vocabulary together. In this analysis, examples include Subunit, Integrin and Αmβ2. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Integrin alpha M, one of the stronger structural bridges in this analysis connects Integrin alpha M with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Integrin alpha M to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Function & Therapeutic significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Integrin alpha M · EN edition · Analysis: TopicsToTalkAbout