Integrin alpha M

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Explore the main themes, entities and connections around Integrin alpha M. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

Leukocytes Transmigration Blood vessels Extracellular matrix Endothelial surface

24 related topics

Therapeutic significance

Autoimmune diseases Systemic lupus erythematosus (SLE)Lupus nephritis Cancer Genome-wide association studies

20 related topics

Overview

Heterodimeric Macrophage-1 antigen Complement receptor Cluster of differentiation Integrin

21 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHO, 1BHQ, 1IDN, 1IDO, 1JLM, 1M1U, 1MF7, 1N9Z, 1NA5, 2LKE, 2LKJ, 3Q3G, 3QA3, 4M76, 4XW2
Band: 16p11.2 · 7|7 F3
Bgee: monocyte · granulocyte · trabecular bone · bone marrow · blood
BioGPS: More reference expression data
Chr.: Chromosome 16 (human) · Chromosome 7 (mouse)

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Map overview Semantic statistics

Nodes69

Edges68

Triples110

Avg. degree1.97

Density0.028986

Components1

How this topic connects Entity context

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Integrin alpha M

Top relations

Gene ontology · 49

Integrin alpha M → amyloid-beta binding, amyloid-beta clearance, apoptotic signaling pathway, cargo receptor activity, cell adhesion, cell surface, cell surface receptor signaling pathway involved in cell-cell signaling, cell-cell adhesion via plasma-membrane adhesion molecules, complement component C3b binding, complement-mediated synapse pruning, cytokine-mediated signaling pathway, ectodermal cell differentiation, external side of plasma membrane, extracellular exosome, extracellular matrix organization, extracellular space, forebrain development, heat shock protein binding, immune system process, innate immune response

Bgee · 17

Integrin alpha M → appendix, blood, bone marrow, bone marrow cell, decidua, dentate gyrus of hippocampal formation granule cell, esophagus, granulocyte, hippocampus proper, ileum, jejunum, monocyte, spleen, striatum of neuraxis, trabecular bone, upper lobe of left lung, uterus

RNA expression pattern · 17

Band · 2

Integrin alpha M → 16p11.2, 7|7 F3

Chr. · 2

Integrin alpha M → Chromosome 16 (human), Chromosome 7 (mouse)

End · 2

Integrin alpha M → 127,717,663 bp, 31,332,892 bp

Aliases · 1

Integrin alpha M → ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M

Available structures · 1

Integrin alpha M → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHO, 1BHQ, 1IDN, 1IDO, 1JLM, 1M1U, 1MF7, 1N9Z, 1NA5, 2LKE, 2LKJ, 3Q3G, 3QA3, 4M76, 4XW2

BioGPS · 1

Integrin alpha M → More reference expression data

Databases · 1

Integrin alpha M → NCBI: entry; OMA: entry

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cd11b itgam integrin also immune cytokines adhesion bp lupus migration involved human αmβ2 cell activation leukocyte leukocytes chr subunit complement

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Integrin alpha M	Aliases	ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6, integrin subunit alpha M	1.00	infobox
Integrin alpha M	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1BHO, 1BHQ, 1IDN, 1IDO, 1JLM, 1M1U, 1MF7, 1N9Z, 1NA5, 2LKE, 2LKJ, 3Q3G, 3QA3, 4M76, 4XW2	1.00	infobox
Integrin alpha M	Band	16p11.2	1.00	infobox
Integrin alpha M	Band	7\|7 F3	1.00	infobox
Integrin alpha M	Bgee	monocyte	1.00	infobox
Integrin alpha M	Bgee	granulocyte	1.00	infobox
Integrin alpha M	Bgee	trabecular bone	1.00	infobox
Integrin alpha M	Bgee	bone marrow	1.00	infobox
Integrin alpha M	Bgee	blood	1.00	infobox
Integrin alpha M	Bgee	bone marrow cell	1.00	infobox
Integrin alpha M	Bgee	spleen	1.00	infobox
Integrin alpha M	Bgee	appendix	1.00	infobox
Integrin alpha M	Bgee	upper lobe of left lung	1.00	infobox
Integrin alpha M	Bgee	decidua	1.00	infobox
Integrin alpha M	Bgee	ileum	1.00	infobox
Integrin alpha M	Bgee	jejunum	1.00	infobox
Integrin alpha M	Bgee	dentate gyrus of hippocampal formation granule cell	1.00	infobox
Integrin alpha M	Bgee	hippocampus proper	1.00	infobox
Integrin alpha M	Bgee	esophagus	1.00	infobox
Integrin alpha M	Bgee	striatum of neuraxis	1.00	infobox
Integrin alpha M	Bgee	uterus	1.00	infobox
Integrin alpha M	BioGPS	More reference expression data	1.00	infobox
Integrin alpha M	Chr.	Chromosome 16 (human)	1.00	infobox
Integrin alpha M	Chr.	Chromosome 7 (mouse)	1.00	infobox
Integrin alpha M	Databases	NCBI: entry; OMA: entry	1.00	infobox
Integrin alpha M	End	31,332,892 bp	1.00	infobox
Integrin alpha M	End	127,717,663 bp	1.00	infobox
Integrin alpha M	Ensembl	ENSG00000169896	1.00	infobox
Integrin alpha M	Entrez	3684	1.00	infobox
Integrin alpha M	External IDs	OMIM: 120980; MGI: 96607; GeneCards: ITGAM	1.00	infobox

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