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Nitric oxide synthase

Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule. It helps modulate vascular tone, insulin secretion, airway tone, and peristalsis, and is involved in angiogenesis and neural development. It may function as a retrograde neurotransmitter.…

Products, Mammalian isoforms & Structure

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BRENDA
enzyme data
CAS no.
125978-95-2
EC no.
1.14.13.39
ExPASy
NiceZyme view
Gene Ontology
AmiGO / QuickGO
KEGG
enzyme entry

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Overview

Species distribution

Function

Mammalian isoforms

Structure

Inhibitors

In non-mammal eukaryotes

In prokaryotes

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Map overview Semantic statistics

Nitric oxide synthase

Nodes113
Edges112
Triples48
Avg. degree1.98
Density0.017699
Components1

How this topic connects Entity context

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Nitric oxide synthase

Top relations

related to eNOS · 13
Nitric oxide synthase → As, BH2, BH4, Ca2, Chromosome, Endothelial NOS, Golgi, N-terminal, NO, NOS, NOS3, The, These
related to External links · 12
Nitric oxide synthase → Chemistry, Edinburgh, Medicine, Medicine Medical Subject Headings, MeSH, National Library, Nitric, NO SynthaseNitric Oxide Synthase, Physiology, Proteopedia, School, The Nobel Prize
related to Chemical reaction · 10
Nitric oxide synthase → L-Arg, L-arginine, L-citrulline, NADPH, Nitric, NO, NOHLA, Nω-hydroxy-L-arginine, O2, Oxidation
BRENDA · 1
Nitric oxide synthase → enzyme data
CAS no. · 1
Nitric oxide synthase → 125978-95-2
EC no. · 1
Nitric oxide synthase → 1.14.13.39
ExPASy · 1
Nitric oxide synthase → NiceZyme view
Gene Ontology · 1
Nitric oxide synthase → AmiGO / QuickGO
KEGG · 1
Nitric oxide synthase → enzyme entry
MetaCyc · 1
Nitric oxide synthase → metabolic pathway

Important terminology Word statistics

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Important terminology

nos nitric oxide enos nnos domain inos endothelial synthase may oxygenase cell function heme electron also reductase nadph calmodulin nos3

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Nitric oxide synthaseBRENDAenzyme data1.00infobox
Nitric oxide synthaseCAS no.125978-95-21.00infobox
Nitric oxide synthaseEC no.1.14.13.391.00infobox
Nitric oxide synthaseExPASyNiceZyme view1.00infobox
Nitric oxide synthaseGene OntologyAmiGO / QuickGO1.00infobox
Nitric oxide synthaseKEGGenzyme entry1.00infobox
Nitric oxide synthaseMetaCycmetabolic pathway1.00infobox
Nitric oxide synthaseNCBIproteins1.00infobox
Nitric oxide synthasePDB structuresRCSB PDB PDBe PDBsum1.00infobox
Nitric oxide synthasePMCarticles1.00infobox
Nitric oxide synthasePubMedarticles1.00infobox
Nitric oxide synthaseRheareactions1.00infobox
Nitric oxide synthaseSearchSearchPMCarticlesPubMedarticlesNCBIproteins1.00infobox

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