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Globin

The globins are a superfamily of heme-containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the globin fold, a series of eight alpha helical segments. Two prominent members include myoglobin and hemoglobin. Both of these proteins reversibly bind oxygen via a heme prosthetic group. They are widely…

Examples, Evolution & Structure

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Key facts & relationships

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AlphaFold
IPR000971 · PF00042
Available protein structures:
IPR000971 · PF00042
CDD
cd01040
ECOD
106.1.1
InterPro
IPR000971
PDB
IPR000971 PF00042 (ECOD; PDBsum)

Topics to explore

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Overview

Structure

Evolution

Subfamilies

Examples

The globin fold

Advanced semantic analysis

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Map overview Semantic statistics

Globin

Nodes97
Edges96
Triples73
Avg. degree1.98
Density0.020619
Components1

How this topic connects Entity context

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Globin

Top relations

related to Evolution · 20
Globin → All, Chimeric, Family, FHb-like, Globin-coupled, Globins, Includes, Single-domain, SSDgb, Subfamily FHb, Subfamily GCS, Subfamily PGb, Subfamily SDgb, Subfamily SSDgb, Subfamily TrHb1, Subfamily TrHb2, Subfamily TrHb3, T1, T2, T3
related to Examples · 12
Globin → CYGBHBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, HBZ, Human, MB
related to Subfamilies · 12
Globin → InterPro, IPR001032Myoglobin InterPro, IPR002335Erythrocruorin InterPro, IPR002336Hemoglobin, IPR002337Hemoglobin, IPR002338Myoglobin, IPR011406Globin, IPR012085Globin, IPR013314Globin, IPR013316Hemoglobin, IPR014610, Leghemoglobin InterPro
related to The globin fold · 5
Globin → N-terminal, RsbN, RsbR, Some, The
related to Sequence conservation · 4
Globin → Although, The, This, While
related to Structure · 3
Globin → Since, The, This
AlphaFold · 2
Globin → IPR000971, PF00042
Available protein structures: · 2
Globin → IPR000971, PF00042
see also · 2
Globin → Biology, C-rich
CDD · 1
Globin → cd01040

Important terminology Word statistics

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Important terminology

fold subfamily oxygen proteins hemoglobin globins protein also chimeric myoglobin structure found family single-domain truncated helix sequence neuroglobin domain eight

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
GlobinAlphaFoldIPR0009711.00infobox
GlobinAlphaFoldPF000421.00infobox
GlobinAvailable protein structures:IPR0009711.00infobox
GlobinAvailable protein structures:PF000421.00infobox
GlobinCDDcd010401.00infobox
GlobinECOD106.1.11.00infobox
GlobinInterProIPR0009711.00infobox
GlobinPDBIPR000971 PF00042 (ECOD; PDBsum)1.00infobox
GlobinPfamPF000421.00infobox
GlobinPfam clanCL00901.00infobox
GlobinPROSITEPS010331.00infobox
GlobinSCOP21hba / SCOPe / SUPFAM1.00infobox
GlobinSymbolGlobin1.00infobox

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    Min side: 3
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