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Globin: Examples, Evolution & Structure

The globins are a superfamily of heme-containing globular proteins, involved in binding and/or transporting oxygen. These proteins all incorporate the globin fold, a series of eight alpha helical segments. Two prominent members include myoglobin and hemoglobin. Both of these proteins reversibly bind oxygen via a heme prosthetic group. They are widely…

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Globin topic overview

The analysis highlights Examples, Evolution and Structure as prominent areas in the source structure around Globin.

Related topics
90
Source areas
6
Connected nodes
96
Extracted relationships
73
Concept neighborhoods
27
Bridge connections
96

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Examples · 48 topics
Evolution · 14 topics
Structure · 11 topics
Overview · 9 topics
Subfamilies · 5 topics
The globin fold · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

AlphaFold
IPR000971 · PF00042
Available protein structures:
IPR000971 · PF00042
CDD
cd01040
ECOD
106.1.1
InterPro
IPR000971
PDB
IPR000971 PF00042 (ECOD; PDBsum)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Structure

Evolution

Subfamilies

Examples

The globin fold

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Globin connects Entity context

The extracted context around Globin shows recurring relationship patterns in the source. For example, Globin → All, Chimeric, Family, FHb-like, Globin-coupled, Globins, Includes, Single-domain, SSDgb, Subfamily FHb, Subfamily GCS, Subfamily PGb, Subfamily SDgb, Subfamily SSDgb, Subfamily TrHb1, Subfamily TrHb2, Subfamily TrHb3, T1, T2, T3 Another extracted example is Globin → CYGBHBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, HBZ, Human, MB. Use these groups to spot repeated connection types before inspecting the individual relationships.

Globin

Top relations

related to Evolution · 20
Globin → All, Chimeric, Family, FHb-like, Globin-coupled, Globins, Includes, Single-domain, SSDgb, Subfamily FHb, Subfamily GCS, Subfamily PGb, Subfamily SDgb, Subfamily SSDgb, Subfamily TrHb1, Subfamily TrHb2, Subfamily TrHb3, T1, T2, T3
related to Examples · 12
Globin → CYGBHBA1, HBA2, HBB, HBD, HBE1, HBG1, HBG2, HBM, HBQ1, HBZ, Human, MB
related to Subfamilies · 12
Globin → InterPro, IPR001032Myoglobin InterPro, IPR002335Erythrocruorin InterPro, IPR002336Hemoglobin, IPR002337Hemoglobin, IPR002338Myoglobin, IPR011406Globin, IPR012085Globin, IPR013314Globin, IPR013316Hemoglobin, IPR014610, Leghemoglobin InterPro
related to The globin fold · 5
Globin → N-terminal, RsbN, RsbR, Some, The
related to Sequence conservation · 4
Globin → Although, The, This, While
related to Structure · 3
Globin → Since, The, This
AlphaFold · 2
Globin → IPR000971, PF00042
Available protein structures: · 2
Globin → IPR000971, PF00042
see also · 2
Globin → Biology, C-rich
CDD · 1
Globin → cd01040

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

fold subfamily oxygen proteins hemoglobin globins protein also chimeric myoglobin structure found family single-domain truncated helix sequence neuroglobin domain eight

Globin relationships Subject–Predicate–Object triples

TTTA extracted 73 structured relationships around Globin. Examples in this analysis include Globin → AlphaFold → IPR000971 and Globin → AlphaFold → PF00042. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
GlobinAlphaFoldIPR0009711.00infobox
GlobinAlphaFoldPF000421.00infobox
GlobinAvailable protein structures:IPR0009711.00infobox
GlobinAvailable protein structures:PF000421.00infobox
GlobinCDDcd010401.00infobox
GlobinECOD106.1.11.00infobox
GlobinInterProIPR0009711.00infobox
GlobinPDBIPR000971 PF00042 (ECOD; PDBsum)1.00infobox
GlobinPfamPF000421.00infobox
GlobinPfam clanCL00901.00infobox
GlobinPROSITEPS010331.00infobox
GlobinSCOP21hba / SCOPe / SUPFAM1.00infobox
GlobinSymbolGlobin1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Globin bring nearby vocabulary together. In this analysis, examples include Fold, Domain and Found. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Globin
    • Fold
    • Domain
    • Found
    • Protein
    • Mutation
    • Eight
    • N-terminal
    • Neuroglobin
    • Structure
    • Myoglobin
    • Sequence
    • Proteins
  • globin
    • Fold
    • Domain
    • Found
    • Protein
    • Mutation
    • Eight
    • N-terminal
    • Neuroglobin
    • Structure
    • Myoglobin
    • Sequence
    • Proteins
  • three-dimensional fold
    • Globin
    • Structure
    • Sequence
    • Also
    • Protein
    • Family
    • Mutation
    • Superfamily
    • Eight
    • Helices
    • Helix
    • Subfamily
  • all-alpha protein fold
    • Globin
    • Hydrophobic
    • Structure
    • Myoglobin
    • Sequence
    • Also
    • Protein
    • Family
    • Hbo
    • Truncated
    • Mutation
    • Superfamily
  • fold
    • Globin
    • Structure
    • Sequence
    • Also
    • Protein
    • Family
    • Mutation
    • Superfamily
    • Eight
    • Helices
    • Helix
    • Subfamily
  • the globin fold
    • Fold
    • Globin
    • Structure
    • Sequence
    • Also
    • Domain
    • Found
    • Protein
    • Family
    • Mutation
    • Eight
    • N-terminal
  • hemoglobin, alpha
    • Myoglobin
    • Proteins
    • Eight
    • Mutation
    • Plants
    • Hydrophobic
    • Involved
    • Myoglobin-like
    • Neuroglobin
    • Helices
    • Helix
    • Protein
  • globular proteins
    • Alpha
    • Involved
    • Eight
    • Globin
    • Bind
    • Oxygen
    • Heme
    • Hydrophobic
    • Mutation
    • Myoglobin-like
    • Superfamily
    • Fold

Connections between topic areas Semantic bridges

For Globin, one of the stronger structural bridges in this analysis connects Globin with Examples. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Globin — Examples · splits 48 ⟂ 49
Globin — Evolution · splits 82 ⟂ 15
Globin — Structure · splits 85 ⟂ 12
Globin — Overview · splits 87 ⟂ 10
Globin — Subfamilies · splits 91 ⟂ 6
Globin — The globin fold · splits 93 ⟂ 4

Map overview Semantic statistics

Globin

Nodes97
Edges96
Triples73
Avg. degree1.98
Density0.020619
Components1

Source & methodology

TTTA analyzes the structure around Globin to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Examples, Evolution & Structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Globin · EN edition · Analysis: TopicsToTalkAbout

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