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NOS1

Nitric oxide synthase 1 (neuronal), also known as NOS1, is an enzyme that in humans is encoded by the NOS1 gene.

[EN, English, English]

Function, Clinical significance & Interactions

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Explore the main themes, entities and connections around NOS1. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

18 related topics

Clinical significance

6 related topics

Interactions

3 related topics

Overview

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

1.14.13.39
Aliases
NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS, nitric oxide synthase 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4D1N, 4UCH, 4UH5, 4UH6, 4V3U, 5ADF, 5ADG, 5ADI, 5FVX, 5FVW, 5FVU, 5FVV
Band
12q24.22 · 5 F|5 57.29 cM
Bgee
body of tongue · biceps brachii · Skeletal muscle tissue of biceps brachii · Skeletal muscle tissue of rectus abdominis · muscle of thigh
BioGPS
More reference expression data

Topics to explore

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Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

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Map overview Semantic statistics

Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.

NOS1

Nodes34
Edges33
Triples163
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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NOS1

Top relations

Gene ontology · 78
NOS1 → arginine binding, arginine catabolic process, cadmium ion binding, calmodulin binding, calyx of Held, caveola, cell projection, cell redox homeostasis, cellular response to growth factor stimulus, cytoplasm, cytoskeleton, cytosol, dendritic spine, flavin adenine dinucleotide binding, FMN binding, heme binding, membrane, membrane raft, metal ion binding, mitochondrion
Bgee · 20
NOS1 → anterior amygdaloid area, biceps brachii, body of tongue, buccal mucosa cell, digastric muscle, dorsal tegmental nucleus, gastrocnemius muscle, lateral hypothalamus, mammillary body, muscle of thigh, pons, pontine nuclei, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, spinal ganglia, sternocleidomastoid muscle, subiculum, temporal muscle, vastus lateralis muscle, ventromedial nucleus
RNA expression pattern · 20
NOS1 → anterior amygdaloid area, biceps brachii, body of tongue, buccal mucosa cell, digastric muscle, dorsal tegmental nucleus, gastrocnemius muscle, lateral hypothalamus, mammillary body, muscle of thigh, pons, pontine nuclei, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, spinal ganglia, sternocleidomastoid muscle, subiculum, temporal muscle, vastus lateralis muscle, ventromedial nucleus
related to Function · 18
NOS1 → Both, EC1, Endothelial NOS, FAD, FMN, In, Inducible NOS, It, L-arginine, NADPH, Neuronal NOS, Nitric, NO, NOS, NOS2, NOS3, NOSs, Various
Band · 2
NOS1 → 12q24.22, 5 F|5 57.29 cM
Chr. · 2
NOS1 → Chromosome 12 (human), Chromosome 5 (mouse)
End · 2
NOS1 → 117,452,170 bp, 118,096,905 bp
related to Interactions · 2
NOS1 → DLG4, NOS1AP
1.14.13.39 · 1
NOS1 → ↗
Aliases · 1
NOS1 → NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS, nitric oxide synthase 1

Important terminology Word statistics

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Important terminology

bp chr human band nitric oxide gene synthase chromosome 12 enzyme also location function neuronal activity mouse nos search 452

Entity relationships Subject–Predicate–Object triples

Extracted RDF-like relationships with confidence and source. The table includes structured facts and lower-confidence contextual relations.
SubjectPredicateObjectConfidenceSrc
NOS11.14.13.391.00infobox
NOS1AliasesNOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS, nitric oxide synthase 11.00infobox
NOS1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4D1N, 4UCH, 4UH5, 4UH6, 4V3U, 5ADF, 5ADG, 5ADI, 5FVX, 5FVW, 5FVU, 5FVV1.00infobox
NOS1Band12q24.221.00infobox
NOS1Band5 F|5 57.29 cM1.00infobox
NOS1Bgeebody of tongue1.00infobox
NOS1Bgeebiceps brachii1.00infobox
NOS1BgeeSkeletal muscle tissue of biceps brachii1.00infobox
NOS1BgeeSkeletal muscle tissue of rectus abdominis1.00infobox
NOS1Bgeemuscle of thigh1.00infobox
NOS1Bgeepons1.00infobox
NOS1Bgeegastrocnemius muscle1.00infobox
NOS1Bgeespinal ganglia1.00infobox
NOS1Bgeebuccal mucosa cell1.00infobox
NOS1Bgeevastus lateralis muscle1.00infobox
NOS1Bgeeanterior amygdaloid area1.00infobox
NOS1Bgeepontine nuclei1.00infobox
NOS1Bgeesubiculum1.00infobox
NOS1Bgeedigastric muscle1.00infobox
NOS1Bgeetemporal muscle1.00infobox
NOS1Bgeemammillary body1.00infobox
NOS1Bgeedorsal tegmental nucleus1.00infobox
NOS1Bgeeventromedial nucleus1.00infobox
NOS1Bgeelateral hypothalamus1.00infobox
NOS1Bgeesternocleidomastoid muscle1.00infobox
NOS1BioGPSMore reference expression data1.00infobox
NOS1Chr.Chromosome 12 (human)1.00infobox
NOS1Chr.Chromosome 5 (mouse)1.00infobox
NOS1DatabasesNCBI: entry; OMA: entry1.00infobox
NOS1End117,452,170 bp1.00infobox

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