Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

IKBKB: Measurement, Interactions & Function

IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta) gene.

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

IKBKB topic overview

The analysis highlights Measurement, Interactions and Function as prominent areas in the source structure around IKBKB.

Related topics
35
Source areas
4
Connected nodes
39
Extracted relationships
130
Concept neighborhoods
12
Bridge connections
39

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Interactions · 15 topics
Function · 14 topics
Clinical significance · 4 topics
Overview · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.7.11.1
2.7.11.10
Aliases
IKBKB, IKK-beta, IKK2, IKKB, IMD15, NFKBIKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa B kinase subunit beta,…
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KIK, 3BRT, 3BRV, 4E3C
Band
8p11.21 · 8|8 A2
Bgee
spleen · granulocyte · right lobe of thyroid gland · right uterine tube · skin of leg

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Clinical significance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How IKBKB connects Entity context

The extracted context around IKBKB shows recurring relationship patterns in the source. For example, IKBKB → anatomical structure morphogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, CD40 receptor complex, cellular response to tumor necrosis factor, cortical actin cytoskeleton organization, cytoplasm, cytoplasmic side of plasma membrane, cytosol, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, I-kappaB phosphorylation, identical protein binding, IkappaB kinase activity, IkappaB kinase complex, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, kinase activity, membrane Another extracted example is IKBKB → blood, crypt of lieberkuhn of small intestine, granulocyte, hair follicle, left lobe of thyroid gland, medullary collecting duct, mesenteric lymph nodes, minor salivary glands, molar, Paneth cell, right lobe of thyroid gland, right uterine tube, skin of abdomen, skin of leg, spleen, stroma of bone marrow, superior cervical ganglion, tonsil, vagina. Use these groups to spot repeated connection types before inspecting the individual relationships.

IKBKB

Top relations

Gene ontology · 53
IKBKB → anatomical structure morphogenesis, antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent, ATP binding, CD40 receptor complex, cellular response to tumor necrosis factor, cortical actin cytoskeleton organization, cytoplasm, cytoplasmic side of plasma membrane, cytosol, Fc-epsilon receptor signaling pathway, I-kappaB kinase/NF-kappaB signaling, I-kappaB phosphorylation, identical protein binding, IkappaB kinase activity, IkappaB kinase complex, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, kinase activity, membrane
Bgee · 19
IKBKB → blood, crypt of lieberkuhn of small intestine, granulocyte, hair follicle, left lobe of thyroid gland, medullary collecting duct, mesenteric lymph nodes, minor salivary glands, molar, Paneth cell, right lobe of thyroid gland, right uterine tube, skin of abdomen, skin of leg, spleen, stroma of bone marrow, superior cervical ganglion, tonsil, vagina
RNA expression pattern · 19
IKBKB → blood, crypt of lieberkuhn of small intestine, granulocyte, hair follicle, left lobe of thyroid gland, medullary collecting duct, mesenteric lymph nodes, minor salivary glands, molar, Paneth cell, right lobe of thyroid gland, right uterine tube, skin of abdomen, skin of leg, spleen, stroma of bone marrow, superior cervical ganglion, tonsil, vagina
related to Interactions · 13
IKBKB → CDC37, CHUKCTNNB1, FANCA, HDAC9, IKBKGIRAK1, IKK-β, MAP3K14, NCOA3, NFKB1, NFKBIA, NFKBIB, PPM1B, TNFRSF1A
Band · 2
IKBKB → 8p11.21, 8|8 A2
Chr. · 2
IKBKB → Chromosome 8 (human), Chromosome 8 (mouse)
End · 2
IKBKB → 23,196,605 bp, 42,332,460 bp
2.7.11.1 · 1
IKBKB → ↗
2.7.11.10 · 1
IKBKB → ↗
Aliases · 1
IKBKB → IKBKB, IKK-beta, IKK2, IKKB, IMD15, NFKBIKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa B kinase subunit beta,…

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

bp chr human band ikk-β kinase gene inhibitor protein factor chromosome iκb nf-κb nuclear subunit location function activity also mouse

IKBKB relationships Subject–Predicate–Object triples

TTTA extracted 130 structured relationships around IKBKB. Examples in this analysis include IKBKB → 2.7.11.1 → ↗ and IKBKB → Aliases → IKBKB, IKK-beta, IKK2, IKKB, IMD15, NFKBIKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa B kinase subunit beta,…. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
IKBKB2.7.11.11.00infobox
IKBKB2.7.11.101.00infobox
IKBKBAliasesIKBKB, IKK-beta, IKK2, IKKB, IMD15, NFKBIKB, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of nuclear factor kappa B kinase subunit beta,…1.00infobox
IKBKBAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4KIK, 3BRT, 3BRV, 4E3C1.00infobox
IKBKBBand8p11.211.00infobox
IKBKBBand8|8 A21.00infobox
IKBKBBgeespleen1.00infobox
IKBKBBgeegranulocyte1.00infobox
IKBKBBgeeright lobe of thyroid gland1.00infobox
IKBKBBgeeright uterine tube1.00infobox
IKBKBBgeeskin of leg1.00infobox
IKBKBBgeeskin of abdomen1.00infobox
IKBKBBgeeminor salivary glands1.00infobox
IKBKBBgeeleft lobe of thyroid gland1.00infobox
IKBKBBgeetonsil1.00infobox
IKBKBBgeevagina1.00infobox
IKBKBBgeemesenteric lymph nodes1.00infobox
IKBKBBgeeblood1.00infobox
IKBKBBgeePaneth cell1.00infobox
IKBKBBgeecrypt of lieberkuhn of small intestine1.00infobox
IKBKBBgeehair follicle1.00infobox
IKBKBBgeemolar1.00infobox
IKBKBBgeemedullary collecting duct1.00infobox
IKBKBBgeesuperior cervical ganglion1.00infobox
IKBKBBgeestroma of bone marrow1.00infobox
IKBKBBioGPSMore reference expression data1.00infobox
IKBKBChr.Chromosome 8 (human)1.00infobox
IKBKBChr.Chromosome 8 (mouse)1.00infobox
IKBKBDatabasesNCBI: entry; OMA: entry1.00infobox
IKBKBEnd42,332,460 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around IKBKB bring nearby vocabulary together. In this analysis, examples include Subunit, Gene and Kinase. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • IKBKB
    • Subunit
    • Gene
    • Kinase
    • B-cells
    • Enhancer
    • Enzyme
    • Kappa
    • Light
    • Polypeptide
    • Search
    • Ikk-β
    • Activity
  • ikbkb
    • Subunit
    • Gene
    • Kinase
    • B-cells
    • Enhancer
    • Enzyme
    • Kappa
    • Light
    • Polypeptide
    • Search
    • Ikk-β
    • Activity
  • gene
    • Location
    • Subunit
    • Chromosome
    • Human
    • Ikbkb
    • Kinase
    • B-cells
    • Bp
    • Chr
    • End
    • Enhancer
    • Enzyme
  • enzyme
    • Search
    • Activity
    • Function
    • Location
    • Subunit
    • Chromosome
    • Factor
    • Gene
    • Human
    • Ikbkb
    • Kinase
    • Bp
  • iκb kinase
    • Subunit
    • Enzyme
    • Kappa
    • Light
    • Nucleus
    • Pathway
    • Polypeptide
    • Search
    • Activity
    • Function
    • Location
    • Nuclear
  • transcription factor
    • Activity
    • Nuclear
    • Subunit
    • Gene
    • Ikbkb
    • Kinase
    • B-cells
    • Beta
    • Enhancer
    • Enzyme
    • Kappa
    • Kappa-b
  • function
    • Enzyme
    • Search
    • Activity
    • Location
    • Protein
    • Subunit
    • Chromosome
    • Gene
    • Human
    • Ikbkb
    • Inhibitor
    • Iκb
  • inhibitor
    • Kappa
    • Light
    • Polypeptide
    • Function
    • Nuclear
    • Protein
    • Subunit
    • Kinase
    • Enzyme
    • Kappa-b
    • Known
    • Search

Connections between topic areas Semantic bridges

For IKBKB, one of the stronger structural bridges in this analysis connects IKBKB with Interactions. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
IKBKBInteractions · splits 24 ⟂ 16
IKBKBFunction · splits 25 ⟂ 15
IKBKBClinical significance · splits 35 ⟂ 5
IKBKBOverview · splits 37 ⟂ 3

Map overview Semantic statistics

IKBKB

Nodes40
Edges39
Triples130
Avg. degree1.95
Density0.05
Components1

Source & methodology

TTTA analyzes the structure around IKBKB to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Measurement, Interactions & Function, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — IKBKB · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.