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Hypothalamic–pituitary–adrenal axis

The hypothalamic–pituitary–adrenal axis (HPA axis) is a neuroendocrine axis that controls the secretion of corticosteroid stress hormones. The HPA axis has three components: the hypothalamus (a part of the brain located below the thalamus), the pituitary gland (a pea-shaped structure located below the hypothalamus), and the adrenal (also called "suprarena…

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Hypothalamic–pituitary–adrenal axis

Nodes118
Edges117
Triples12
Avg. degree1.98
Density0.016949
Components1

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stress hpa axis cortisol system hypothalamus immune pituitary crh acth response neuroendocrine adrenal brain vasopressin glucocorticoids also body systems hormones

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SubjectPredicateObjectConfidenceSrc
cortisol from cholesterolinstance ofwhere it rapidly stimulates the biosynthesis of corticosteroids0.80text
the amygdalainstance ofand optimize survival.Anatomical connections between brain areas0.80text
hippocampusinstance ofand optimize survival.Anatomical connections between brain areas0.80text
prefrontal cortexinstance ofand optimize survival.Anatomical connections between brain areas0.80text
hypothalamus facilitate activation of the HPA axisinstance ofand optimize survival.Anatomical connections between brain areas0.80text
fatigueinstance ofInteractions between the proinflammatory cytokines and the brain can alter the metabolic activity of neurotransmitters and cause symptoms0.80text
depressioninstance ofInteractions between the proinflammatory cytokines and the brain can alter the metabolic activity of neurotransmitters and cause symptoms0.80text
and mood changesinstance ofInteractions between the proinflammatory cytokines and the brain can alter the metabolic activity of neurotransmitters and cause symptoms0.80text
attention deficitsinstance ofand with behavior disorders0.80text
schizophreniainstance ofand with behavior disorders0.80text
anxietyinstance ofand with behavior disorders0.80text
depressioninstance ofand with behavior disorders0.80text

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