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Adrenocorticotropic hormone

Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along…

History, Production and regulation & Associated conditions

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Key facts & relationships

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Domains
InterPro
HGNC
9201
Locus
Chr. 2 p23
NCBI gene
5443
OMIM
176830
RefSeq
NM_000939

Topics to explore

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Overview

Production and regulation

Structure

Function

ACTH receptors outside the adrenal gland

History

Associated conditions

Advanced semantic analysis

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Map overview Semantic statistics

Adrenocorticotropic hormone

Nodes81
Edges80
Triples21
Avg. degree1.98
Density0.024691
Components1

How this topic connects Entity context

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Adrenocorticotropic hormone

Top relations

related to Associated conditions · 8
Adrenocorticotropic hormone → ACTH, ACTHHypopituitarism, ACTHSmall, Addison's, Critical, Cushing's, Diseases, POIS
Domains · 1
Adrenocorticotropic hormone → InterPro
HGNC · 1
Adrenocorticotropic hormone → 9201
Locus · 1
Adrenocorticotropic hormone → Chr. 2 p23
NCBI gene · 1
Adrenocorticotropic hormone → 5443
OMIM · 1
Adrenocorticotropic hormone → 176830
RefSeq · 1
Adrenocorticotropic hormone → NM_000939
Search for · 1
Adrenocorticotropic hormone → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Adrenocorticotropic hormone → Swiss-model
Symbol · 1
Adrenocorticotropic hormone → POMC

Important terminology Word statistics

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Important terminology

acth adrenal also production hormone pituitary gland hypothalamus pomc disease cortisol cells insufficiency secreted cortex produced actions response stimulates cleavage

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Adrenocorticotropic hormoneDomainsInterPro1.00infobox
Adrenocorticotropic hormoneHGNC92011.00infobox
Adrenocorticotropic hormoneLocusChr. 2 p231.00infobox
Adrenocorticotropic hormoneNCBI gene54431.00infobox
Adrenocorticotropic hormoneOMIM1768301.00infobox
Adrenocorticotropic hormoneRefSeqNM_0009391.00infobox
Adrenocorticotropic hormoneSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Adrenocorticotropic hormoneStructuresSwiss-model1.00infobox
Adrenocorticotropic hormoneSymbolPOMC1.00infobox
Adrenocorticotropic hormoneUniProtP011891.00infobox
phosphorylationinstance ofwhich undergoes a series of post-translational modifications0.80text
glycosylation before it is proteolytically cleaved by endopeptidases to yield various polypeptide fragments with varying physiological activityinstance ofwhich undergoes a series of post-translational modifications0.80text

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