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NSD2: Overview, Related Topics & Entities

Probable histone-lysine N-methyltransferase NSD2 is an enzyme that in humans is encoded by the NSD2 gene.

Language: English [EN]
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NSD2 topic overview

The analysis highlights Overview, Related Topics and Entities as prominent areas in the source structure around NSD2.

Related topics
13
Source areas
1
Connected nodes
14
Extracted relationships
91
Concept neighborhoods
11
Bridge connections
14

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 13 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

2.1.1.357
Aliases
NSD2, MMSET, REIIBP, TRX5, WHS, WHSC1, Wolf-Hirschhorn syndrome candidate 1, nuclear receptor binding SET domain protein 2, KMT3G, KMT3F, RAUST
Band
4p16.3 · 5|5 B2
Bgee
ventricular zone · ganglionic eminence · sural nerve · right testis · left testis
BioGPS
More reference expression data
Chr.
Chromosome 4 (human) · Chromosome 5 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How NSD2 connects Entity context

The extracted context around NSD2 shows recurring relationship patterns in the source. For example, NSD2 → anatomical structure morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, bone development, chromatin, chromatin binding, chromatin organization, chromosome, cytoplasm, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, double-strand break repair via nonhomologous end joining, histone H3-K36 methylation, histone H4-K20 methylation, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity, membranous septum morphogenesis, metal ion binding, methylation Another extracted example is NSD2 → bone marrow cell, ganglionic eminence, genital tubercle, hand, lateral geniculate nucleus, lateral septal nucleus, left testis, male germ cell, otic vesicle, right testis, secondary oocyte, sperm, stromal cell of endometrium, superior cervical ganglion, sural nerve, tail of embryo, ventricular zone, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

NSD2

Top relations

Gene ontology · 32
NSD2 → anatomical structure morphogenesis, atrial septum primum morphogenesis, atrial septum secundum morphogenesis, bone development, chromatin, chromatin binding, chromatin organization, chromosome, cytoplasm, DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, double-strand break repair via nonhomologous end joining, histone H3-K36 methylation, histone H4-K20 methylation, histone methyltransferase activity (H3-K36 specific), histone methyltransferase activity (H4-K20 specific), histone-lysine N-methyltransferase activity, membranous septum morphogenesis, metal ion binding, methylation
Bgee · 18
NSD2 → bone marrow cell, ganglionic eminence, genital tubercle, hand, lateral geniculate nucleus, lateral septal nucleus, left testis, male germ cell, otic vesicle, right testis, secondary oocyte, sperm, stromal cell of endometrium, superior cervical ganglion, sural nerve, tail of embryo, ventricular zone, yolk sac
RNA expression pattern · 18
NSD2 → bone marrow cell, ganglionic eminence, genital tubercle, hand, lateral geniculate nucleus, lateral septal nucleus, left testis, male germ cell, otic vesicle, right testis, secondary oocyte, sperm, stromal cell of endometrium, superior cervical ganglion, sural nerve, tail of embryo, ventricular zone, yolk sac
Band · 2
NSD2 → 4p16.3, 5|5 B2
Chr. · 2
NSD2 → Chromosome 4 (human), Chromosome 5 (mouse)
End · 2
NSD2 → 1,982,207 bp, 34,055,319 bp
2.1.1.357 · 1
NSD2 → ↗
Aliases · 1
NSD2 → NSD2, MMSET, REIIBP, TRX5, WHS, WHSC1, Wolf-Hirschhorn syndrome candidate 1, nuclear receptor binding SET domain protein 2, KMT3G, KMT3F, RAUST
BioGPS · 1
NSD2 → More reference expression data
Databases · 1
NSD2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene chromosome bp chr human band whs protein location multiple transcript variants enzyme mouse histone-lysine n-methyltransferase domain set expressed development

NSD2 relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around NSD2. Examples in this analysis include NSD2 → 2.1.1.357 → ↗ and NSD2 → Aliases → NSD2, MMSET, REIIBP, TRX5, WHS, WHSC1, Wolf-Hirschhorn syndrome candidate 1, nuclear receptor binding SET domain protein 2, KMT3G, KMT3F, RAUST. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
NSD22.1.1.3571.00infobox
NSD2AliasesNSD2, MMSET, REIIBP, TRX5, WHS, WHSC1, Wolf-Hirschhorn syndrome candidate 1, nuclear receptor binding SET domain protein 2, KMT3G, KMT3F, RAUST1.00infobox
NSD2Band4p16.31.00infobox
NSD2Band5|5 B21.00infobox
NSD2Bgeeventricular zone1.00infobox
NSD2Bgeeganglionic eminence1.00infobox
NSD2Bgeesural nerve1.00infobox
NSD2Bgeeright testis1.00infobox
NSD2Bgeeleft testis1.00infobox
NSD2Bgeesecondary oocyte1.00infobox
NSD2Bgeebone marrow cell1.00infobox
NSD2Bgeemale germ cell1.00infobox
NSD2Bgeestromal cell of endometrium1.00infobox
NSD2Bgeesperm1.00infobox
NSD2Bgeehand1.00infobox
NSD2Bgeesuperior cervical ganglion1.00infobox
NSD2Bgeeotic vesicle1.00infobox
NSD2Bgeetail of embryo1.00infobox
NSD2Bgeeyolk sac1.00infobox
NSD2Bgeelateral septal nucleus1.00infobox
NSD2Bgeegenital tubercle1.00infobox
NSD2Bgeelateral geniculate nucleus1.00infobox
NSD2BioGPSMore reference expression data1.00infobox
NSD2Chr.Chromosome 4 (human)1.00infobox
NSD2Chr.Chromosome 5 (mouse)1.00infobox
NSD2DatabasesNCBI: entry; OMA: entry1.00infobox
NSD2End1,982,207 bp1.00infobox
NSD2End34,055,319 bp1.00infobox
NSD2EnsemblENSG000001096851.00infobox
NSD2Entrez74681.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around NSD2 bring nearby vocabulary together. In this analysis, examples include Activity, Binding and Enzyme. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • NSD2
    • Activity
    • Binding
    • Enzyme
    • Location
    • Protein
    • Gene
    • Human
    • Bp
    • Chr
    • Chromosome
    • Encoded
    • Humans
  • nsd2
    • Activity
    • Binding
    • Enzyme
    • Location
    • Protein
    • Gene
    • Human
    • Bp
    • Chr
    • Chromosome
    • Encoded
    • Humans
  • gene
    • Location
    • Nsd2
    • Protein
    • Human
    • Bp
    • Chr
    • Chromosome
    • Activity
    • Binding
    • Domain
    • End
    • Histone-lysine
  • chromosome 4
    • Human
    • Bp
    • Chr
    • Location
    • Band
    • Activity
    • Binding
    • End
    • Mouse
    • Syndrome
    • Wolf-hirschhorn
    • Gene
  • enzyme
    • Nsd2
    • Encoded
    • Humans
    • Probable
    • Activity
    • Binding
    • Domain
    • Histone-lysine
    • N-methyltransferase
    • Set
    • Syndrome
    • Wolf-hirschhorn
  • wolf-hirschhorn syndrome
    • Syndrome
    • Wolf-hirschhorn
    • Whs
    • Hemizygous
    • Chromosome
    • Activity
    • Binding
    • Domain
    • Enzyme
    • Set
    • Location
    • Nsd2
  • nonsense-mediated mrna
    • Reference
    • Activity
    • Binding
    • End
    • Expressed
    • Mouse
    • N-methyltransferase
    • Transcript
    • Variants
    • Location
    • Nsd2
    • Protein
  • set domains
    • Several
    • Activity
    • Binding
    • Syndrome
    • Wolf-hirschhorn
    • Location
    • Whs
    • Human
    • Bp
    • Chr
    • Chromosome

Connections between topic areas Semantic bridges

Bridges highlight paths between different parts of the NSD2 map and can reveal research angles that are easy to miss in a flat list.

Min side: 3

Map overview Semantic statistics

NSD2

Nodes15
Edges14
Triples91
Avg. degree1.87
Density0.133333
Components1

Source & methodology

TTTA analyzes the structure around NSD2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Overview, Related Topics & Entities, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — NSD2 · EN edition · Analysis: TopicsToTalkAbout

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