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Fc fragment of IgG receptor IIb (coded by FCGR2B gene) is a low affinity inhibitory receptor for the Fc region of immunoglobulin gamma (IgG). FCGR2B participates in the phagocytosis of immune complexes and in the regulation of antibody production by B lymphocytes.
The analysis highlights Art, Regions and Products as prominent areas in the source structure around FCGR2B.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around FCGR2B shows recurring relationship patterns in the source. For example, FCGR2B → amyloid-beta binding, antigen processing and presentation of exogenous peptide antigen via MHC class II, cell body, cellular response to amyloid-beta, cellular response to molecule of bacterial origin, cerebellum development, cytoplasm, defense response, dendritic spine, external side of plasma membrane, Fc-gamma receptor signaling pathway involved in phagocytosis, follicular B cell differentiation, follicular dendritic cell activation, IgG binding, immune complex clearance by monocytes and macrophages, immune response, immunoglobulin mediated immune response, inflammatory response, integral component of membrane, integral component of plasma membrane Another extracted example is FCGR2B → appendix, blood, calvaria, granulocyte, lymph node, molar, monocyte, motor neuron, placenta, right coronary artery, right kidney, skin of abdomen, spleen, stroma of bone marrow, synovial joint, synovial membrane, tibiofemoral joint. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
cells immune fcγriib bp human complexes receptor chr band activation bcr gene chromosome dendritic igg expression function inhibitory antibody phagocytosis
TTTA extracted 164 structured relationships around FCGR2B. Examples in this analysis include FCGR2B → Aliases → FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb, FcRII-c, FCGR2C and FCGR2B → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2FCB, 3WJJ,%%s3WJL. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| FCGR2B | Aliases | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb, FcRII-c, FCGR2C | 1.00 | infobox |
| FCGR2B | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2FCB, 3WJJ,%%s3WJL | 1.00 | infobox |
| FCGR2B | Band | 1q23.3 | 1.00 | infobox |
| FCGR2B | Band | 1 H3|1 78.02 cM | 1.00 | infobox |
| FCGR2B | Bgee | placenta | 1.00 | infobox |
| FCGR2B | Bgee | right coronary artery | 1.00 | infobox |
| FCGR2B | Bgee | blood | 1.00 | infobox |
| FCGR2B | Bgee | spleen | 1.00 | infobox |
| FCGR2B | Bgee | monocyte | 1.00 | infobox |
| FCGR2B | Bgee | lymph node | 1.00 | infobox |
| FCGR2B | Bgee | synovial membrane | 1.00 | infobox |
| FCGR2B | Bgee | synovial joint | 1.00 | infobox |
| FCGR2B | Bgee | granulocyte | 1.00 | infobox |
| FCGR2B | Bgee | appendix | 1.00 | infobox |
| FCGR2B | Bgee | stroma of bone marrow | 1.00 | infobox |
| FCGR2B | Bgee | tibiofemoral joint | 1.00 | infobox |
| FCGR2B | Bgee | calvaria | 1.00 | infobox |
| FCGR2B | Bgee | skin of abdomen | 1.00 | infobox |
| FCGR2B | Bgee | right kidney | 1.00 | infobox |
| FCGR2B | Bgee | molar | 1.00 | infobox |
| FCGR2B | Bgee | motor neuron | 1.00 | infobox |
| FCGR2B | BioGPS | n/a | 1.00 | infobox |
| FCGR2B | Chr. | Chromosome 1 (human) | 1.00 | infobox |
| FCGR2B | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| FCGR2B | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| FCGR2B | End | 161,678,654 bp | 1.00 | infobox |
| FCGR2B | End | 170,804,116 bp | 1.00 | infobox |
| FCGR2B | Ensembl | ENSG00000072694 | 1.00 | infobox |
| FCGR2B | Entrez | 2213 | 1.00 | infobox |
| FCGR2B | External IDs | OMIM: 604590; MGI: 95499; GeneCards: FCGR2B | 1.00 | infobox |
The concept neighborhoods around FCGR2B bring nearby vocabulary together. In this analysis, examples include Dendritic, Cells and Immune. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For FCGR2B, one of the stronger structural bridges in this analysis connects FCGR2B with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around FCGR2B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Art, Regions & Products, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — FCGR2B · EN edition · Analysis: TopicsToTalkAbout