Glucose-6-phosphate dehydrogenase deficiency

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Pathophysiology

Enzyme Pentose phosphate pathway Glucose-6-phosphate 6-phosphoglucono-δ-lactone Metabolic pathway

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Cause

Hallmark Antimalarials Moth balls Naphthalene Bacterial

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Diagnosis

Complete blood count Reticulocyte Heinz bodies Blood film Liver enzymes

13 related topics

Signs and symptoms

Asymptomatic X-linked Lyonization Skewed X-inactivation Red blood cells

12 related topics

Key facts & relationships

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Causes: Genetic (X-linked recessive)
Complications: Anemia, newborn jaundice
Deaths: 33,000 (2015)
Diagnostic method: Based on symptoms, blood test, genetic testing
Differential diagnosis: Pyruvate kinase deficiency, hereditary spherocytosis, sickle cell anemia
Frequency: 400 million

Topics to explore

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Overview

Anemia
Inborn error of metabolism Inborn errors of carbohydrate metabolism
Hemolysis
Yellowish skin Jaundice
Shortness of breath
Newborn jaundice
X-linked recessive
Glucose-6-phosphate dehydrogenase
Red blood cells
Reactive oxygen species
Infections Infection
Fava beans
Mutation
Genetic testing
Falafel
Blood transfusions
Bili lights Bili light
Primaquine
Mediterranean
Middle East
Antimalarial drugs Antimalarial drug
Methylene blue
Henna
Rasburicase
Clinical Pharmacogenetics Implementation Consortium

Signs and symptoms

Treatment

Prognosis

Epidemiology

History

Illinois State Penitentiary
Cr51 Chromium

Society and culture

Greco-Roman era Greco-Roman world
Pythagoras
Pythagoreans Pythagoreanism

Advanced semantic analysis

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Map overview Semantic statistics

Glucose-6-phosphate dehydrogenase deficiency

Nodes131

Edges130

Triples18

Avg. degree1.98

Density0.015267

Components1

How this topic connects Entity context

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Glucose-6-phosphate dehydrogenase deficiency

Top relations

Causes · 1

Glucose-6-phosphate dehydrogenase deficiency → Genetic (X-linked recessive)

Complications · 1

Glucose-6-phosphate dehydrogenase deficiency → Anemia, newborn jaundice

Deaths · 1

Glucose-6-phosphate dehydrogenase deficiency → 33,000 (2015)

Diagnostic method · 1

Glucose-6-phosphate dehydrogenase deficiency → Based on symptoms, blood test, genetic testing

Differential diagnosis · 1

Glucose-6-phosphate dehydrogenase deficiency → Pyruvate kinase deficiency, hereditary spherocytosis, sickle cell anemia

Frequency · 1

Glucose-6-phosphate dehydrogenase deficiency → 400 million

Other names · 1

Glucose-6-phosphate dehydrogenase deficiency → Favism

Risk factors · 1

Glucose-6-phosphate dehydrogenase deficiency → Triggered by infections, certain medications, stress, foods such as fava beans

Specialty · 1

Glucose-6-phosphate dehydrogenase deficiency → Medical genetics

Symptoms · 1

Glucose-6-phosphate dehydrogenase deficiency → Yellowish skin, dark urine, shortness of breath

Important terminology Word statistics

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Important terminology

g6pd deficiency blood red cells enzyme beans symptoms people may glucose-6-phosphate dehydrogenase anemia hemolysis certain fava favism foods jaundice hemolytic

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Glucose-6-phosphate dehydrogenase deficiency	Causes	Genetic (X-linked recessive)	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Complications	Anemia, newborn jaundice	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Deaths	33,000 (2015)	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Diagnostic method	Based on symptoms, blood test, genetic testing	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Differential diagnosis	Pyruvate kinase deficiency, hereditary spherocytosis, sickle cell anemia	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Frequency	400 million	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Other names	Favism	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Risk factors	Triggered by infections, certain medications, stress, foods such as fava beans	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Specialty	Medical genetics	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Symptoms	Yellowish skin, dark urine, shortness of breath	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Treatment	Avoiding triggers, medications for infection, stopping offending medication, blood transfusions	1.00	infobox
Glucose-6-phosphate dehydrogenase deficiency	Usual onset	Within a few days of a trigger	1.00	infobox

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