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Primaquine: History, Applications & Research

Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. It is an alternative treatment for Pneumocystis pneumonia together with clindamycin. It is taken…

Language: English [EN]
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Primaquine topic overview

The analysis highlights History, Applications and Research as prominent areas in the source structure around Primaquine.

Related topics
40
Source areas
7
Connected nodes
47
Extracted relationships
79
Concept neighborhoods
21
Bridge connections
47

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Overview · 15 topics
Medical uses · 12 topics
Adverse reactions · 4 topics
Chemistry · 3 topics
History · 3 topics
Research · 2 topics
Pharmacology · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
P01BA03 (WHO)
Bioavailability
96%
CAS Number
90-34-6 Y
ChEBI
CHEBI:8405 Y

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Medical uses

Adverse reactions

Pharmacology

Chemistry

History

Research

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Primaquine connects Entity context

The extracted context around Primaquine shows recurring relationship patterns in the source. For example, Primaquine → It, Jasoprim, Malirid, Neo-Quipenyl, Pimaquin, Pmq, Primachina, Primacin, Primaquina, Primaquine Phosphate, Remaquin, SN-13272 Another extracted example is Primaquine → As, But, Clarity, Disease Control, If, It, Plasmodium, Prevention, US Centers, Use. Use these groups to spot repeated connection types before inspecting the individual relationships.

Primaquine

Top relations

related to Names · 12
Primaquine → It, Jasoprim, Malirid, Neo-Quipenyl, Pimaquin, Pmq, Primachina, Primacin, Primaquina, Primaquine Phosphate, Remaquin, SN-13272
related to Malaria · 10
Primaquine → As, But, Clarity, Disease Control, If, It, Plasmodium, Prevention, US Centers, Use
related to history · 7
Primaquine → Columbia University, Development, Office, Pacific, Robert Elderfield, Scientific Research, World War II
related to External links · 5
Primaquine → Archived, Drug Information Portal, January, Medicine, National Library
related to Pharmacokinetics · 4
Primaquine → Administration, In, Renal, With
related to Pneumocystis pneumonia · 4
Primaquine → AIDS, PCP, Pneumocystis, To
related to Special populations · 3
Primaquine → G6PD, However, WHO
related to Adverse reactions · 2
Primaquine → Common, In
related to Mechanism of action · 2
Primaquine → However, Liver
3D model (JSmol) · 1
Primaquine → Interactive image

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vivax malaria blood deficiency g6pd used action pneumocystis pneumonia also people due liver drug ovale effects medication drugs names falciparum

Primaquine relationships Subject–Predicate–Object triples

TTTA extracted 79 structured relationships around Primaquine. Examples in this analysis include Primaquine → 3D model (JSmol) → Interactive image and Primaquine → AHFS/Drugs.com → Monograph. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Primaquine3D model (JSmol)Interactive image1.00infobox
PrimaquineAHFS/Drugs.comMonograph1.00infobox
PrimaquineATC codeP01BA03 (WHO)1.00infobox
PrimaquineBioavailability96%1.00infobox
PrimaquineCAS Number90-34-6 Y1.00infobox
PrimaquineChEBICHEBI:8405 Y1.00infobox
PrimaquineChEMBLChEMBL506 Y1.00infobox
PrimaquineChemSpider4739 Y1.00infobox
PrimaquineChiralityRacemic mixture1.00infobox
PrimaquineCompTox Dashboard (EPA)DTXSID80235091.00infobox
PrimaquineDrugBankDB01087 Y1.00infobox
PrimaquineECHA InfoCard100.001.8071.00infobox
PrimaquineElimination half-life6 hours1.00infobox
PrimaquineFormulaC15H21N3O1.00infobox
PrimaquineKEGGD08420 Y1.00infobox
PrimaquineLegal statusUS: ℞-only1.00infobox
PrimaquineLicense dataUS DailyMed: Primaquine1.00infobox
PrimaquineMedlinePlusa6070371.00infobox
PrimaquineMetabolismLiver1.00infobox
PrimaquineMolar mass259.353 g·mol−11.00infobox
PrimaquineOther namesprimaquine phosphate1.00infobox
PrimaquinePubChem CID49081.00infobox
PrimaquineRoutes of administrationBy mouth1.00infobox
PrimaquineUNIIMVR3634GX11.00infobox
Primaquinecausesmethemoglobinemia0.90text
Primaquineis amedication used to treat and prevent malaria and to treat Pneumocystis pneumonia0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Primaquine bring nearby vocabulary together. In this analysis, examples include Blood, Vivax and Also. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Primaquine
    • Blood
    • Vivax
    • Also
    • Deficiency
    • People
    • G6pd
    • Drugs
    • Malaria
    • Used
    • Administration
    • Cell
    • Dehydrogenase
  • primaquine
    • Blood
    • Vivax
    • Also
    • Deficiency
    • People
    • G6pd
    • Drugs
    • Malaria
    • Used
    • Administration
    • Cell
    • Dehydrogenase
  • malaria
    • Used
    • Relapse
    • Due
    • Ovale
    • Pneumocystis
    • Pneumonia
    • Vivax
    • Action
    • Medication
    • Mouth
    • Names
    • Administration
  • plasmodium vivax
    • Ovale
    • Relapse
    • Liver
    • Primaquine
    • Also
    • Malaria
    • Blood
    • High
    • Due
    • Action
    • Used
    • Mouth
  • immunosuppressive drugs
    • Due
    • Pneumocystis
    • Pneumonia
    • People
    • Used
    • Mouth
    • Names
    • Administration
    • First
    • Number
    • Relapse
    • Treat
  • pneumocystis pneumonia
    • Pneumonia
    • Used
    • Drugs
    • Clindamycin
    • Mouth
    • Names
    • Administration
    • Number
    • Relapse
    • Treat
    • Due
    • Ovale
  • glucose-6-phosphate dehydrogenase (g6pd) deficiency
    • Dehydrogenase
    • Glucose-6-phosphate
    • Deficiency
    • G6pd
    • Hemolytic
    • May
    • Pregnancy
    • Cell
    • Red
    • Due
    • People
    • Primaquine
  • red blood cell breakdown
    • Also
    • Blood
    • Cell
    • People
    • Red
    • Primaquine
    • Dehydrogenase
    • Glucose-6-phosphate
    • Include
    • Number
    • Vivax
    • Due

Connections between topic areas Semantic bridges

For Primaquine, one of the stronger structural bridges in this analysis connects Primaquine with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Primaquine — Overview · splits 32 ⟂ 16
Primaquine — Medical uses · splits 35 ⟂ 13
Primaquine — Adverse reactions · splits 43 ⟂ 5
Primaquine — Chemistry · splits 44 ⟂ 4
Primaquine — History · splits 44 ⟂ 4
Primaquine — Research · splits 45 ⟂ 3

Map overview Semantic statistics

Primaquine

Nodes48
Edges47
Triples79
Avg. degree1.96
Density0.041667
Components1

Source & methodology

TTTA analyzes the structure around Primaquine to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History, Applications & Research, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Primaquine · EN edition · Analysis: TopicsToTalkAbout

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