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X-inactivation

X-inactivation (also called Lyonization, after English geneticist Mary Lyon) is a process by which one of the copies of the X chromosome is inactivated in therian female mammals. The inactive X chromosome is silenced by being packaged into a transcriptionally inactive structure called heterochromatin. As nearly all female mammals have two X chromosomes…

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Mechanism

Uses in experimental biology

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X-inactivation

Nodes100
Edges99
Triples22
Avg. degree1.98
Density0.02
Components1

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X-inactivation

Top relations

related to Chromosomal component · 9
X-inactivation → Chromosomal, Ftx, Jpx, RNA, The X-inactivation, The XIC, Tsix, XIC, Xist
related to Cycle of X-chromosome activation in rodents · 6
X-inactivation → Each, In, The, Thereafter, This, XI
see also · 3
X-inactivation → Early, Sex-determination, X-inactivationCalico
part of · 1
X-inactivation → the activation cycle of the X chromosome throughout the female life

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Important terminology

chromosome inactivation genes one xist gene cells chromosomes cell females inactivated rna xi heterozygous female x-chromosome inactive mammals needed xa

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
X-inactivationpart ofthe activation cycle of the X chromosome throughout the female life0.85text
humansinstance ofThe choice of which X chromosome will be inactivated in a particular embryonic cell is random in placental mammals0.80text
but once an X chromosome is inactivated it will remain inactive throughout the lifetime of the cellinstance ofThe choice of which X chromosome will be inactivated in a particular embryonic cell is random in placental mammals0.80text
its descendants in the organisminstance ofThe choice of which X chromosome will be inactivated in a particular embryonic cell is random in placental mammals0.80text
X-inactivationrelated to Chromosomal componentThe X-inactivation0.60section
X-inactivationrelated to Chromosomal componentXIC0.60section
X-inactivationrelated to Chromosomal componentChromosomal0.60section
X-inactivationrelated to Chromosomal componentThe XIC0.60section
X-inactivationrelated to Chromosomal componentRNA0.60section
X-inactivationrelated to Chromosomal componentXist0.60section
X-inactivationrelated to Chromosomal componentTsix0.60section
X-inactivationrelated to Chromosomal componentJpx0.60section

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