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Sex linkage

Sex linkage describes the sex-specific patterns of inheritance and presentation when a gene mutation (allele) is present on a sex chromosome (allosome) rather than a non-sex chromosome (autosome). In humans, these are termed X-linked recessive, X-linked dominant and Y-linked. The inheritance and presentation of all three differ depending on the sex of…

History, X-linked diseases & Overview

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Overview

Background

X-linked patterns of inheritance

X-linked dominant inheritance

X-linked recessive inheritance

X-linked diseases

Screening for genetic diseases

Y-linked inheritance

Sex chromosome aneuploidy

Sex-linkage in animals

History

Related terms

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Map overview Semantic statistics

Sex linkage

Nodes198
Edges197
Triples36
Avg. degree1.99
Density0.010101
Components1

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Sex linkage

Top relations

related to background · 14
Sex linkage → For, However, In, Sex, SRY, The, The X-chromosome, The Y-chromosome, There, X-chromosome, X-chromosomes, X-linked, Y-chromosome, Y-linked

Important terminology Word statistics

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Important terminology

x-linked gene chromosome males affected inheritance females genes genetic sex recessive x-chromosome male chromosomes syndrome condition dominant one mutations y-linked

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
skewed X-inactivation or somatic mosaicism is difficult to reconcile with standard definitions of dominanceinstance ofstating that the highly variable penetrance of X-linked traits in females as a result of mechanisms0.80text
recessivenessinstance ofstating that the highly variable penetrance of X-linked traits in females as a result of mechanisms0.80text
a long faceinstance ofalong with distinct physical features0.80text
large or protruding earsinstance ofalong with distinct physical features0.80text
flat feetinstance ofalong with distinct physical features0.80text
and low muscle toneinstance ofalong with distinct physical features0.80text
bitinginstance ofand self-injurious behaviors0.80text
respiratory failureinstance ofaffected individuals are likely to develop complications0.80text
cardiomyopathyinstance ofaffected individuals are likely to develop complications0.80text
heart failureinstance ofaffected individuals are likely to develop complications0.80text
next-generation sequencing or Polymerase Chain Reactioninstance ofsaliva sample or buccal swab and using laboratory techniques0.80text
gonadsinstance ofand an affected individual will lack male sexual characteristics0.80text

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