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Rasburicase

Rasburicase, sold under the brand name Elitek in the US and Fasturtec in the EU, is a medication that helps to clear uric acid from the blood. It is a recombinant version of urate oxidase, an enzyme that metabolizes uric acid to allantoin. Urate oxidase is known to be present in many mammals but does not naturally occur in humans. Rasburicase is produced…

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AHFS/Drugs.com
Monograph
ATC code
V03AF07 (WHO)
Bioavailability
N/A
CAS Number
134774-45-1 Y
ChEMBL
ChEMBL1201594 N
ChemSpider
none

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Overview

Medical uses

Side effects

Pharmacology

Society and culture

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Map overview Semantic statistics

Rasburicase

Nodes37
Edges36
Triples54
Avg. degree1.95
Density0.054054
Components1

How this topic connects Entity context

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Rasburicase

Top relations

related to Contraindication · 8
Rasburicase → G6PDH, Giemsa-stained, HBHA, Heinz, RBCs, The, These, While Heinz
related to Medical uses · 7
Rasburicase → Drug Administration, European, Food, For, However, It, TLS
related to Pharmacokinetics · 7
Rasburicase → AUC0-24, Caucasians, Cmax, In, Japanese, Minimal, The
Legal status · 4
Rasburicase → AU: S4 (Prescription only), EU: Rx-only, In general: ℞ (Prescription only), US: ℞-only
related to Pharmacodynamics · 3
Rasburicase → Following, The, There
has effect · 2
Rasburicase → G6PDH, Testing
AHFS/Drugs.com · 1
Rasburicase → Monograph
ATC code · 1
Rasburicase → V03AF07 (WHO)
Bioavailability · 1
Rasburicase → N/A
CAS Number · 1
Rasburicase → 134774-45-1 Y

Important terminology Word statistics

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Important terminology

acid uric administration urate oxidase patients mg elitek 15 kg blood adult pediatric strain reconstitution pharmacokinetics name us fasturtec eu

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
RasburicaseAHFS/Drugs.comMonograph1.00infobox
RasburicaseATC codeV03AF07 (WHO)1.00infobox
RasburicaseBioavailabilityN/A1.00infobox
RasburicaseCAS Number134774-45-1 Y1.00infobox
RasburicaseChEMBLChEMBL1201594 N1.00infobox
RasburicaseChemSpidernone1.00infobox
RasburicaseDrugBankDB00049 Y1.00infobox
RasburicaseECHA InfoCard100.207.6861.00infobox
RasburicaseElimination half-life18 hrs1.00infobox
RasburicaseFormulaC1521H2381N417O461S71.00infobox
RasburicaseIUPHAR/BPS74671.00infobox
RasburicaseKEGGD057041.00infobox
RasburicaseLegal statusAU: S4 (Prescription only)1.00infobox
RasburicaseLegal statusUS: ℞-only1.00infobox
RasburicaseLegal statusEU: Rx-only1.00infobox
RasburicaseLegal statusIn general: ℞ (Prescription only)1.00infobox
RasburicaseLicense dataUS DailyMed: Rasburicase1.00infobox
RasburicaseMolar mass34109.66 g·mol−11.00infobox
RasburicasePregnancy categoryAU: B21.00infobox
RasburicaseRoutes of administrationIntravenous infusion1.00infobox
RasburicaseTrade namesElitek, Fasturtec1.00infobox
RasburicaseUNII08GY9K1EUO1.00infobox

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    Min side: 3
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