Factor VII

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Physiology

Thrombin Tissue factor pathway inhibitor Vitamin K Liver Warfarin

8 related topics

Overview

EC Protein Coagulation Gene Enzyme

15 related topics

Medical uses

Factor VIII Israeli Intracerebral hemorrhage

3 related topics

Role in disease

Factor VII deficiency AryoSeven

2 related topics

Key facts & relationships

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3.4.21.21: ↗
Aliases: F7, SPCA, coagulation factor VII
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YT7, 1BF9, 1CVW, 1DAN, 1DVA, 1F7E, 1F7M, 1FAK, 1FF7, 1FFM, 1J9C, 1JBU, 1KLI, 1KLJ, 1O5D, 1QFK, 1W0Y, 1W2K,…
Band: 13q34 · 8 A1.1|8 5.73 cM
Bgee: right lobe of liver · tendon of biceps brachii · testicle · ventral tegmental area · secondary oocyte
BioGPS: More reference expression data

Topics to explore

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Overview

EC Enzyme Commission number
Protein
Coagulation
Gene
Enzyme
Serine protease
Tissue factor
Factor IX
Factor X
Genetic recombination
Recombinant factor VIIa
FDA
Hemophilia
Biosimilar
Bypassing agent Bypassing agent?action=edit&redlink=1

Physiology

Genetics

Chromosome 13

Role in disease

Medical uses

Interactions

Interact Protein-protein interaction

Advanced semantic analysis

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Map overview Semantic statistics

Nodes37

Edges36

Triples160

Avg. degree1.95

Density0.054054

Components1

How this topic connects Entity context

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Factor VII

Top relations

Gene ontology · 48

Factor VII → animal organ regeneration, blood coagulation, blood coagulation, extrinsic pathway, calcium ion binding, circadian rhythm, collagen-containing extracellular matrix, endopeptidase activity, endoplasmic reticulum lumen, endoplasmic reticulum to Golgi vesicle-mediated transport, extracellular region, extracellular space, Golgi lumen, hemostasis, hydrolase activity, peptidase activity, plasma membrane, positive regulation of blood coagulation, positive regulation of cell migration, positive regulation of leukocyte chemotaxis, positive regulation of platelet-derived growth factor receptor signaling pathway

Bgee · 20

Factor VII → carotid body, choroid plexus of fourth ventricle, decidua, deltoid muscle, embryo, entorhinal cortex, Ileal epithelium, jejunum, left lobe of liver, pancreatic ductal cell, retinal pigment epithelium, right lobe of liver, right lung lobe, secondary oocyte, stroma of bone marrow, tendon of biceps brachii, testicle, ventral tegmental area, visceral pleura, yolk sac

RNA expression pattern · 20

related to Physiology · 19

Factor VII → FVII, FVIIa, FVIIa-TF, IIa, IX, IXa, K-dependent, Once, TF, TF/factor III, TFPI, The, Tissue, Upon, Use, VII, VIIa, Xa, XIIa

related to Medical uses · 12

Factor VII → AryoSeven, Factor VIII, However, In, Israeli, It, IX, NovoSeven, Recombinant, Risks, The, VIIa

related to External links · 7

Factor VII → Archived, Comprehensive Health Education Services, LLC, MEROPS, Official, S01, Wayback MachineCHES

related to Role in disease · 6

Factor VII → AryoSeven, FVII, Gene, It, NovoSeven, VIIa

Band · 2

Factor VII → 13q34, 8 A1.1|8 5.73 cM

Chr. · 2

Factor VII → Chromosome 13 (human), Chromosome 8 (mouse)

End · 2

Factor VII → 113,120,685 bp, 13,085,809 bp

Important terminology Word statistics

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Important terminology

factor vii coagulation gene tissue bp human eptacog chr band protein viia recombinant chromosome 13 activated ix fvii bleeding xa

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
Factor VII	3.4.21.21	↗	1.00	infobox
Factor VII	Aliases	F7, SPCA, coagulation factor VII	1.00	infobox
Factor VII	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4YT7, 1BF9, 1CVW, 1DAN, 1DVA, 1F7E, 1F7M, 1FAK, 1FF7, 1FFM, 1J9C, 1JBU, 1KLI, 1KLJ, 1O5D, 1QFK, 1W0Y, 1W2K,…	1.00	infobox
Factor VII	Band	13q34	1.00	infobox
Factor VII	Band	8 A1.1\|8 5.73 cM	1.00	infobox
Factor VII	Bgee	right lobe of liver	1.00	infobox
Factor VII	Bgee	tendon of biceps brachii	1.00	infobox
Factor VII	Bgee	testicle	1.00	infobox
Factor VII	Bgee	ventral tegmental area	1.00	infobox
Factor VII	Bgee	secondary oocyte	1.00	infobox
Factor VII	Bgee	visceral pleura	1.00	infobox
Factor VII	Bgee	pancreatic ductal cell	1.00	infobox
Factor VII	Bgee	deltoid muscle	1.00	infobox
Factor VII	Bgee	jejunum	1.00	infobox
Factor VII	Bgee	retinal pigment epithelium	1.00	infobox
Factor VII	Bgee	left lobe of liver	1.00	infobox
Factor VII	Bgee	right lung lobe	1.00	infobox
Factor VII	Bgee	yolk sac	1.00	infobox
Factor VII	Bgee	decidua	1.00	infobox
Factor VII	Bgee	embryo	1.00	infobox
Factor VII	Bgee	entorhinal cortex	1.00	infobox
Factor VII	Bgee	stroma of bone marrow	1.00	infobox
Factor VII	Bgee	carotid body	1.00	infobox
Factor VII	Bgee	Ileal epithelium	1.00	infobox
Factor VII	Bgee	choroid plexus of fourth ventricle	1.00	infobox
Factor VII	BioGPS	More reference expression data	1.00	infobox
Factor VII	Chr.	Chromosome 13 (human)	1.00	infobox
Factor VII	Chr.	Chromosome 8 (mouse)	1.00	infobox
Factor VII	Databases	NCBI: entry; OMA: entry	1.00	infobox
Factor VII	End	113,120,685 bp	1.00	infobox

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