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Doxycycline

Doxycycline, sold under the brand names Vibramycin and Doryx, among others, is a broad-spectrum antibiotic of the tetracycline class used in the treatment of infections caused by bacteria and certain parasites. It is used to treat bacterial pneumonia, acne, chlamydia infections, Lyme disease, cholera, typhus, and syphilis, and is sometimes used to…

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3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
J01AA02 (WHO) A01AB22 (WHO)
Bioavailability
~100%
CAS Number
564-25-0
ChEBI
CHEBI:60648

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Overview

Medical uses

Contraindications

Adverse effects

Interactions

Pharmacology

Chemistry

History

Research

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Map overview Semantic statistics

Doxycycline

Nodes327
Edges326
Triples138
Avg. degree1.99
Density0.006116
Components1

How this topic connects Entity context

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Doxycycline

Top relations

related to history · 18
Doxycycline → After, American Cyanamid, As, Both, Charlie Stephens, Drug Administration, FDA, Instead, International Rectifier, International Rectifier's, Lloyd Conover, Pfizer, Rachelle Laboratories, Scientists, Shortly, US, US Food, World War II
related to Anti-inflammatory agent · 10
Doxycycline → Cytokines, ECM, IL-1, IL-10, IL-6, MMP7, MMPs, NF-κB, Some, TNF-α
related to Pregnancy and lactation · 9
Doxycycline → CDC, Disease Control, FDA, However, Other, Prevention, The, The FDA, The US Centers
has effect · 6
Doxycycline → Adverse, An, Clostridioides, One, Oral, The
related to Absorption and excretion · 6
Doxycycline → About, By, CSF, It, The, Very
related to Antimalarial · 6
Doxycycline → As, By, For, Plasmodium, These, This
related to Dosing · 6
Doxycycline → Although, As, Compared, For, Lyme, Therefore
related to Medical uses · 6
Doxycycline → Beyond, Gram-negative, Gram-positive, Like, Lyme, The
related to Spectrum of susceptibility · 6
Doxycycline → Chlamydia, Mycoplasma, Representative, Streptococcus, The, Ureaplasma
related to Chemistry · 5
Doxycycline → C-6, Expired, Fanconi, In, Nevertheless

Important terminology Word statistics

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Important terminology

used tetracycline treatment disease infections bacteria acne anti-inflammatory rosacea also malaria antibiotic drug including effects use treat may lyme conditions

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Doxycycline3D model (JSmol)Interactive image1.00infobox
DoxycyclineAHFS/Drugs.comMonograph1.00infobox
DoxycyclineATC codeJ01AA02 (WHO) A01AB22 (WHO)1.00infobox
DoxycyclineBioavailability~100%1.00infobox
DoxycyclineCAS Number564-25-01.00infobox
DoxycyclineChEBICHEBI:606481.00infobox
DoxycyclineChEMBLChEMBL14331.00infobox
DoxycyclineChemSpider104821061.00infobox
DoxycyclineCompTox Dashboard (EPA)DTXSID00376531.00infobox
DoxycyclineDrugBankDB002541.00infobox
DoxycyclineECHA InfoCard100.008.4291.00infobox
DoxycyclineElimination half-life10–22 hours1.00infobox
DoxycyclineExcretionMainly feces, 40% urine1.00infobox
DoxycyclineFormulaC22H24N2O81.00infobox
DoxycyclineKEGGD078761.00infobox
DoxycyclineLegal statusAU: S4 (Prescription only)1.00infobox
DoxycyclineLegal statusUK: POM (Prescription only)1.00infobox
DoxycyclineLegal statusUS: ℞-only1.00infobox
DoxycyclineLicense dataUS DailyMed: Doxycycline1.00infobox
DoxycyclineMedlinePlusa6820631.00infobox
DoxycyclineMetabolismNegligible1.00infobox
DoxycyclineMolar mass444.440 g·mol−11.00infobox
DoxycyclinePregnancy categoryAU: D1.00infobox
DoxycyclinePronunciation/ˌdɒksɪˈsaɪkliːn/ DOKS-ih-SYE-kleen1.00infobox
DoxycyclineProtein binding80–90%1.00infobox
DoxycyclinePubChem CIDDoxycycline1.00infobox
DoxycyclineRoutes of administrationBy mouth, intravenous1.00infobox
DoxycyclineTrade namesVibramycin, Doryx, others1.00infobox
DoxycyclineUNII334895S8621.00infobox
Doxycyclineis ainhibitor of matrix metalloproteases0.90text

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