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Tissue transglutaminase (abbreviated as tTG or TG2) is a 78-kDa, calcium-dependent enzyme (EC 2.3.2.13) of the protein-glutamine γ-glutamyltransferases family (or simply transglutaminase family). Like other transglutaminases, it crosslinks proteins between an ε-amino group of a lysine residue and a γ-carboxamide group of glutamine residue, creating an…
Clinical significance, Function & Structure
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| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Tissue transglutaminase | 2.3.2.13 | ↗ | 1.00 | infobox |
| Tissue transglutaminase | 3.5.1.44 | ↗ | 1.00 | infobox |
| Tissue transglutaminase | Aliases | TGM2, G-ALPHA-h, GNAH, HEL-S-45, TG2, TGC, TG(C), transglutaminase 2, G(h), hTG2, tTG | 1.00 | infobox |
| Tissue transglutaminase | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4PYG, 1KV3, 2Q3Z, 3LY6, 3S3J, 3S3P, 3S3S | 1.00 | infobox |
| Tissue transglutaminase | Band | 20q11.23 | 1.00 | infobox |
| Tissue transglutaminase | Band | 2 H1|2 78.72 cM | 1.00 | infobox |
| Tissue transglutaminase | Bgee | beta cell | 1.00 | infobox |
| Tissue transglutaminase | Bgee | right coronary artery | 1.00 | infobox |
| Tissue transglutaminase | Bgee | left coronary artery | 1.00 | infobox |
| Tissue transglutaminase | Bgee | canal of the cervix | 1.00 | infobox |
| Tissue transglutaminase | Bgee | popliteal artery | 1.00 | infobox |
| Tissue transglutaminase | Bgee | tibial arteries | 1.00 | infobox |
| Tissue transglutaminase | Bgee | right auricle of heart | 1.00 | infobox |
| Tissue transglutaminase | Bgee | right uterine tube | 1.00 | infobox |
| Tissue transglutaminase | Bgee | upper lobe of left lung | 1.00 | infobox |
| Tissue transglutaminase | Bgee | decidua | 1.00 | infobox |
| Tissue transglutaminase | Bgee | conjunctival fornix | 1.00 | infobox |
| Tissue transglutaminase | Bgee | Paneth cell | 1.00 | infobox |
| Tissue transglutaminase | Bgee | tunica media of zone of aorta | 1.00 | infobox |
| Tissue transglutaminase | Bgee | ascending aorta | 1.00 | infobox |
| Tissue transglutaminase | Bgee | right lung lobe | 1.00 | infobox |
| Tissue transglutaminase | Bgee | ciliary body | 1.00 | infobox |
| Tissue transglutaminase | Bgee | mesenteric lymph nodes | 1.00 | infobox |
| Tissue transglutaminase | Bgee | efferent ductule | 1.00 | infobox |
| Tissue transglutaminase | Bgee | carotid body | 1.00 | infobox |
| Tissue transglutaminase | Bgee | external carotid artery | 1.00 | infobox |
| Tissue transglutaminase | BioGPS | More reference expression data | 1.00 | infobox |
| Tissue transglutaminase | Chr. | Chromosome 20 (human) | 1.00 | infobox |
| Tissue transglutaminase | Chr. | Chromosome 2 (mouse) | 1.00 | infobox |
| Tissue transglutaminase | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
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