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Extracellular signal-regulated kinases

In molecular biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines…

Overview, Mitogen-activated protein kinase 1 & Clinical significance

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Alt. symbols
PRKM2, PRKM1
Domains
InterPro
HGNC
6871
Locus
Chr. 22 q11.2
NCBI gene
5594
OMIM
176948

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Overview

Mitogen-activated protein kinase 1

Mitogen-activated protein kinase 3

Mitogen-activated protein kinase 7

Clinical significance

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Extracellular signal-regulated kinases

Nodes46
Edges45
Triples25
Avg. degree1.96
Density0.043478
Components1

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Extracellular signal-regulated kinases

Top relations

related to External links · 12
Extracellular signal-regulated kinases → Cell Migration Gateway Archived, Extracellular, Kinase Resource Archived, Kinases, MAP, MAPK1MAPK3 Info, Medicine Medical Subject Headings, MeSH, National Library, Signal-Regulated, The Extracellular Signal-Regulated KinasesMAP, Wayback Machine
Alt. symbols · 1
Extracellular signal-regulated kinases → PRKM2, PRKM1
Domains · 1
Extracellular signal-regulated kinases → InterPro
HGNC · 1
Extracellular signal-regulated kinases → 6871
Locus · 1
Extracellular signal-regulated kinases → Chr. 22 q11.2
NCBI gene · 1
Extracellular signal-regulated kinases → 5594
OMIM · 1
Extracellular signal-regulated kinases → 176948
RefSeq · 1
Extracellular signal-regulated kinases → NM_002745
Search for · 1
Extracellular signal-regulated kinases → Search forStructuresSwiss-modelDomainsInterPro
Structures · 1
Extracellular signal-regulated kinases → Swiss-model

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Important terminology

protein kinases mapk1 kinase ras extracellular signal-regulated erks mapk mitogen-activated activation map cells erk pathway mapk3 cell also growth receptors

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Extracellular signal-regulated kinasesAlt. symbolsPRKM2, PRKM11.00infobox
Extracellular signal-regulated kinasesDomainsInterPro1.00infobox
Extracellular signal-regulated kinasesHGNC68711.00infobox
Extracellular signal-regulated kinasesLocusChr. 22 q11.21.00infobox
Extracellular signal-regulated kinasesNCBI gene55941.00infobox
Extracellular signal-regulated kinasesOMIM1769481.00infobox
Extracellular signal-regulated kinasesRefSeqNM_0027451.00infobox
Extracellular signal-regulated kinasesSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Extracellular signal-regulated kinasesStructuresSwiss-model1.00infobox
Extracellular signal-regulated kinasesSymbolMAPK11.00infobox
Extracellular signal-regulated kinasesUniProtP284821.00infobox
HER2instance ofor receptors0.80text

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