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Duffy antigen system: History & Community

Duffy antigen/chemokine receptor (DARC), also known as Fy glycoprotein (FY) or CD234 (Cluster of Differentiation 234), is a protein that in humans is encoded by the ACKR1 gene.

Language: English [EN]
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Duffy antigen system topic overview

The analysis highlights History and Community as prominent areas in the source structure around Duffy antigen system.

Related topics
148
Source areas
8
Connected nodes
156
Extracted relationships
85
Concept neighborhoods
27
Bridge connections
156

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Genetics and genomics · 37 topics
Population genetics · 34 topics
Molecular biology · 29 topics
Clinical significance · 25 topics
Overview · 11 topics
History · 8 topics
Clinical diagnostic · 2 topics
Transfusion data · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
ACKR1, atypical chemokine receptor 1 (Duffy blood group), CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, DARC, DARC/ACKR1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NUU, 4NUV
Band
1q23.2 · 1 H3|1 80.33 cM
Bgee
vena cava · left uterine tube · gastric mucosa · subcutaneous adipose tissue · pericardium
BioGPS
n/a
Chr.
Chromosome 1 (human) · Chromosome 1 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History

Genetics and genomics

Molecular biology

Population genetics

Clinical significance

Clinical diagnostic

Transfusion data

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Duffy antigen system connects Entity context

The extracted context around Duffy antigen system shows recurring relationship patterns in the source. For example, Duffy antigen system → bone marrow, canal of the cervix, cerebellar cortex, coronary artery, ectocervix, gastric mucosa, hippocampus proper, hypothalamus, layer of retina, left uterine tube, neural layer of retina, olfactory bulb, olfactory zone of nasal mucosa, pericardium, primary visual cortex, striatum of neuraxis, subcutaneous adipose tissue, superior frontal gyrus, tibial nerve, vena cava Another extracted example is Duffy antigen system → C-C chemokine binding, chemokine binding, chemokine-mediated signaling pathway, defense response, early endosome, endosome, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, inflammatory response, integral component of membrane, membrane, plasma membrane, protein binding, recycling endosome, regulation of chemokine production, signal transducer activity, signal transduction, signaling receptor activity, transmembrane signaling receptor activity. Use these groups to spot repeated connection types before inspecting the individual relationships.

Duffy antigen system

Top relations

Bgee · 20
Duffy antigen system → bone marrow, canal of the cervix, cerebellar cortex, coronary artery, ectocervix, gastric mucosa, hippocampus proper, hypothalamus, layer of retina, left uterine tube, neural layer of retina, olfactory bulb, olfactory zone of nasal mucosa, pericardium, primary visual cortex, striatum of neuraxis, subcutaneous adipose tissue, superior frontal gyrus, tibial nerve, vena cava
RNA expression pattern · 20
Duffy antigen system → bone marrow, canal of the cervix, cerebellar cortex, coronary artery, ectocervix, gastric mucosa, hippocampus proper, hypothalamus, layer of retina, left uterine tube, neural layer of retina, olfactory bulb, olfactory zone of nasal mucosa, pericardium, primary visual cortex, striatum of neuraxis, subcutaneous adipose tissue, superior frontal gyrus, tibial nerve, vena cava
Gene ontology · 19
Duffy antigen system → C-C chemokine binding, chemokine binding, chemokine-mediated signaling pathway, defense response, early endosome, endosome, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, inflammatory response, integral component of membrane, membrane, plasma membrane, protein binding, recycling endosome, regulation of chemokine production, signal transducer activity, signal transduction, signaling receptor activity, transmembrane signaling receptor activity
Band · 2
Duffy antigen system → 1 H3|1 80.33 cM, 1q23.2
Chr. · 2
Duffy antigen system → Chromosome 1 (human), Chromosome 1 (mouse)
End · 2
Duffy antigen system → 159,206,500 bp, 173,161,317 bp
Aliases · 1
Duffy antigen system → ACKR1, atypical chemokine receptor 1 (Duffy blood group), CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, DARC, DARC/ACKR1
Available structures · 1
Duffy antigen system → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NUU, 4NUV
BioGPS · 1
Duffy antigen system → n/a
Databases · 1
Duffy antigen system → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

duffy antigen gene fy darc receptor blood protein also vivax allele appears malaria mutation erythrocytes human found cells binding associated

Duffy antigen system relationships Subject–Predicate–Object triples

TTTA extracted 85 structured relationships around Duffy antigen system. Examples in this analysis include Duffy antigen system → Aliases → ACKR1, atypical chemokine receptor 1 (Duffy blood group), CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, DARC, DARC/ACKR1 and Duffy antigen system → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NUU, 4NUV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Duffy antigen systemAliasesACKR1, atypical chemokine receptor 1 (Duffy blood group), CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, DARC, DARC/ACKR11.00infobox
Duffy antigen systemAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4NUU, 4NUV1.00infobox
Duffy antigen systemBand1q23.21.00infobox
Duffy antigen systemBand1 H3|1 80.33 cM1.00infobox
Duffy antigen systemBgeevena cava1.00infobox
Duffy antigen systemBgeeleft uterine tube1.00infobox
Duffy antigen systemBgeegastric mucosa1.00infobox
Duffy antigen systemBgeesubcutaneous adipose tissue1.00infobox
Duffy antigen systemBgeepericardium1.00infobox
Duffy antigen systemBgeetibial nerve1.00infobox
Duffy antigen systemBgeeolfactory zone of nasal mucosa1.00infobox
Duffy antigen systemBgeeectocervix1.00infobox
Duffy antigen systemBgeecoronary artery1.00infobox
Duffy antigen systemBgeecanal of the cervix1.00infobox
Duffy antigen systemBgeecerebellar cortex1.00infobox
Duffy antigen systemBgeelayer of retina1.00infobox
Duffy antigen systemBgeeneural layer of retina1.00infobox
Duffy antigen systemBgeebone marrow1.00infobox
Duffy antigen systemBgeeprimary visual cortex1.00infobox
Duffy antigen systemBgeesuperior frontal gyrus1.00infobox
Duffy antigen systemBgeestriatum of neuraxis1.00infobox
Duffy antigen systemBgeehippocampus proper1.00infobox
Duffy antigen systemBgeeolfactory bulb1.00infobox
Duffy antigen systemBgeehypothalamus1.00infobox
Duffy antigen systemBioGPSn/a1.00infobox
Duffy antigen systemChr.Chromosome 1 (human)1.00infobox
Duffy antigen systemChr.Chromosome 1 (mouse)1.00infobox
Duffy antigen systemDatabasesNCBI: entry; OMA: entry1.00infobox
Duffy antigen systemEnd159,206,500 bp1.00infobox
Duffy antigen systemEnd173,161,317 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Duffy antigen system bring nearby vocabulary together. In this analysis, examples include Duffy, Negative and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Duffy antigen system
    • Duffy
    • Negative
    • Receptor
    • Blood
    • Vivax
    • Gene
    • Cell
    • Erythrocytes
    • Individuals
    • Found
    • Fy
    • Chemokine
  • duffy antigen system
    • Duffy
    • Negative
    • Receptor
    • Blood
    • Vivax
    • Gene
    • Cell
    • Erythrocytes
    • Individuals
    • Found
    • Role
    • Fy
  • gene
    • Chromosome
    • Mouse
    • Receptor
    • Protein
    • Blood
    • Human
    • Mutation
    • Bp
    • Population
    • Cell
    • Associated
    • Known
  • red blood cells
    • Erythrocytes
    • Darc
    • Expression
    • Duffy
    • Binding
    • Fy
    • Gene
    • Cells
    • Chromosome
    • Neutrophil
    • Population
    • Role
  • antigen
    • Duffy
    • Receptor
    • Vivax
    • Role
    • Chemokine
    • Erythrocytes
    • Negative
    • Appears
    • Gene
    • Also
    • Blood
    • Cell
  • black people
    • African
    • Found
    • Population
    • Whites
    • Risk
    • Allele
    • Bp
    • Chromosome
    • Mouse
    • Cell
    • Chemokine
    • Duffy
  • nucleated red blood cells
    • Erythrocytes
    • Darc
    • Expression
    • Duffy
    • Binding
    • Fy
    • Gene
    • Cells
    • Chromosome
    • Neutrophil
    • Population
    • Role
  • sickle cell anaemia
    • Expression
    • Duffy
    • Infection
    • Associated
    • Gene
    • Bp
    • Chromosome
    • Darc
    • Population
    • Whites
    • Chemokine
    • Erythrocytes

Connections between topic areas Semantic bridges

For Duffy antigen system, one of the stronger structural bridges in this analysis connects Duffy antigen system with Genetics and genomics. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Duffy antigen systemGenetics and genomics · splits 119 ⟂ 38
Duffy antigen systemPopulation genetics · splits 122 ⟂ 35
Duffy antigen systemMolecular biology · splits 127 ⟂ 30
Duffy antigen systemClinical significance · splits 131 ⟂ 26
Duffy antigen systemOverview · splits 145 ⟂ 12
Duffy antigen systemHistory · splits 148 ⟂ 9
Duffy antigen systemClinical diagnostic · splits 154 ⟂ 3
Duffy antigen systemTransfusion data · splits 154 ⟂ 3

Map overview Semantic statistics

Duffy antigen system

Nodes157
Edges156
Triples85
Avg. degree1.99
Density0.012739
Components1

Source & methodology

TTTA analyzes the structure around Duffy antigen system to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Community, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Duffy antigen system · EN edition · Analysis: TopicsToTalkAbout

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