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Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin-like molecules. Due to these roles, it is…
Clinical significance, Function & Genomics
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pf4 platelet human bp factor chr band chemokine chromosome gene also heparin blood location expression thrombocytopenia role cytokine antibodies mouse
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Platelet factor 4 | Aliases | PF4, CXCL4, PF-4, SCYB4, platelet factor 4 | 1.00 | infobox |
| Platelet factor 4 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes1RHP, 1DN3, 1F9Q, 1F9R, 1F9S, 1PFM, 1PFN, 4R9W, 4R9Y, 4RAU | 1.00 | infobox |
| Platelet factor 4 | Band | 4q13.3 | 1.00 | infobox |
| Platelet factor 4 | Band | 5|5 E1 | 1.00 | infobox |
| Platelet factor 4 | Bgee | monocyte | 1.00 | infobox |
| Platelet factor 4 | Bgee | trabecular bone | 1.00 | infobox |
| Platelet factor 4 | Bgee | granulocyte | 1.00 | infobox |
| Platelet factor 4 | Bgee | blood | 1.00 | infobox |
| Platelet factor 4 | Bgee | gonad | 1.00 | infobox |
| Platelet factor 4 | Bgee | bone marrow | 1.00 | infobox |
| Platelet factor 4 | Bgee | testicle | 1.00 | infobox |
| Platelet factor 4 | Bgee | bone marrow cell | 1.00 | infobox |
| Platelet factor 4 | Bgee | periodontal fiber | 1.00 | infobox |
| Platelet factor 4 | Bgee | spleen | 1.00 | infobox |
| Platelet factor 4 | Bgee | tibiofemoral joint | 1.00 | infobox |
| Platelet factor 4 | Bgee | sciatic nerve | 1.00 | infobox |
| Platelet factor 4 | Bgee | stroma of bone marrow | 1.00 | infobox |
| Platelet factor 4 | Bgee | fetal liver hematopoietic progenitor cell | 1.00 | infobox |
| Platelet factor 4 | Bgee | dermis | 1.00 | infobox |
| Platelet factor 4 | Bgee | ankle | 1.00 | infobox |
| Platelet factor 4 | Bgee | vestibular sensory epithelium | 1.00 | infobox |
| Platelet factor 4 | Bgee | carotid body | 1.00 | infobox |
| Platelet factor 4 | BioGPS | More reference expression data | 1.00 | infobox |
| Platelet factor 4 | Chr. | Chromosome 4 (human) | 1.00 | infobox |
| Platelet factor 4 | Chr. | Chromosome 5 (mouse) | 1.00 | infobox |
| Platelet factor 4 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| Platelet factor 4 | End | 73,982,027 bp | 1.00 | infobox |
| Platelet factor 4 | End | 90,921,242 bp | 1.00 | infobox |
| Platelet factor 4 | Ensembl | ENSG00000163737 | 1.00 | infobox |
| Platelet factor 4 | Entrez | 5196 | 1.00 | infobox |
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