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Transcriptome instability is a genome-wide, pre-mRNA splicing-related characteristic of certain cancers. In general, pre-mRNA splicing is dysregulated in a high proportion of cancerous cells. For certain types of cancer, like in colorectal and prostate, the number of splicing errors per cancer has been shown to vary greatly between individual cancers, a…
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transcriptome instability splicing cancers pre-mrna certain cells colorectal prostate dnmt3a genome-wide splicing-related characteristic general dysregulated high proportion cancerous types cancer
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| Transcriptome instability | is a | genome-wide | 0.90 | text |
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