DNMT3L

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Explore the main themes, entities and connections around DNMT3L. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Function

CpG methylation Epigenetic X-chromosome inactivation DNA methylation DNA methyltransferases

7 related topics

Interactions

Interact HDAC1

2 related topics

Overview

Enzyme Gene

2 related topics

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases: DNMT3L, DNA methyltransferase 3 like
Available structures: Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PV0, 2PVC, 2QRV, 4U7P, 4U7T
Band: 21q22.3 · 10 C1|10 39.72 cM
Bgee: testicle · liver · right lobe of liver · human kidney · gonad
BioGPS: More reference expression data
Chr.: Chromosome 21 (human) · Chromosome 10 (mouse)

Topics to explore

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Overview

Function

CpG methylation CpG site
Epigenetic
X-chromosome inactivation
DNA methylation
DNA methyltransferases DNA methyltransferase
DNA cytosine methyltransferase 3 alpha DNA (cytosine-5)-methyltransferase 3A
Histone deacetylase 1

Interactions

Interact Protein-protein interaction
HDAC1

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

Map overview Semantic statistics

Nodes15

Edges14

Triples85

Avg. degree1.87

Density0.133333

Components1

How this topic connects Entity context

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DNMT3L

Top relations

Gene ontology · 23

DNMT3L → cell differentiation, cytosol, DNA methylation, DNA methylation involved in gamete generation, DNA methylation on cytosine, DNA-binding transcription factor activity, RNA polymerase II-specific, enzyme activator activity, enzyme binding, enzyme regulator activity, ESC/E(Z) complex, male meiosis I, metal ion binding, negative regulation of DNA methylation, negative regulation of transcription, DNA-templated, nucleus, positive regulation of catalytic activity, positive regulation of DNA methylation, protein binding, regulation of catalytic activity, regulation of gene expression by genetic imprinting

Bgee · 19

DNMT3L → blastocyst, embryo, gonad, Gonadal ridge, granulocyte, human kidney, liver, lymph node, morula, mucosa of transverse colon, primary oocyte, renal cortex, right lobe of liver, secondary oocyte, spermatid, testicle, tonsil, transitional epithelium of urinary bladder, zygote

RNA expression pattern · 19

Band · 2

DNMT3L → 10 C1|10 39.72 cM, 21q22.3

Chr. · 2

DNMT3L → Chromosome 10 (mouse), Chromosome 21 (human)

End · 2

DNMT3L → 44,262,216 bp, 77,899,456 bp

Aliases · 1

DNMT3L → DNMT3L, DNA methyltransferase 3 like

Available structures · 1

DNMT3L → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PV0, 2PVC, 2QRV, 4U7P, 4U7T

BioGPS · 1

DNMT3L → More reference expression data

Databases · 1

DNMT3L → NCBI: entry; OMA: entry

Important terminology Word statistics

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Important terminology

dna bp gene chr human band chromosome 21 protein methylation location function enzyme mouse methyltransferase search 262 216 end 44

Entity relationships Subject–Predicate–Object triples

Subject	Predicate	Object	Confidence	Src
DNMT3L	Aliases	DNMT3L, DNA methyltransferase 3 like	1.00	infobox
DNMT3L	Available structures	Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2PV0, 2PVC, 2QRV, 4U7P, 4U7T	1.00	infobox
DNMT3L	Band	21q22.3	1.00	infobox
DNMT3L	Band	10 C1\|10 39.72 cM	1.00	infobox
DNMT3L	Bgee	testicle	1.00	infobox
DNMT3L	Bgee	liver	1.00	infobox
DNMT3L	Bgee	right lobe of liver	1.00	infobox
DNMT3L	Bgee	human kidney	1.00	infobox
DNMT3L	Bgee	gonad	1.00	infobox
DNMT3L	Bgee	lymph node	1.00	infobox
DNMT3L	Bgee	renal cortex	1.00	infobox
DNMT3L	Bgee	granulocyte	1.00	infobox
DNMT3L	Bgee	tonsil	1.00	infobox
DNMT3L	Bgee	mucosa of transverse colon	1.00	infobox
DNMT3L	Bgee	transitional epithelium of urinary bladder	1.00	infobox
DNMT3L	Bgee	primary oocyte	1.00	infobox
DNMT3L	Bgee	blastocyst	1.00	infobox
DNMT3L	Bgee	zygote	1.00	infobox
DNMT3L	Bgee	morula	1.00	infobox
DNMT3L	Bgee	secondary oocyte	1.00	infobox
DNMT3L	Bgee	Gonadal ridge	1.00	infobox
DNMT3L	Bgee	spermatid	1.00	infobox
DNMT3L	Bgee	embryo	1.00	infobox
DNMT3L	BioGPS	More reference expression data	1.00	infobox
DNMT3L	Chr.	Chromosome 21 (human)	1.00	infobox
DNMT3L	Chr.	Chromosome 10 (mouse)	1.00	infobox
DNMT3L	Databases	NCBI: entry; OMA: entry	1.00	infobox
DNMT3L	End	44,262,216 bp	1.00	infobox
DNMT3L	End	77,899,456 bp	1.00	infobox
DNMT3L	Ensembl	ENSG00000142182	1.00	infobox

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