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DNA (cytosine-5)-methyltransferase 3A (DNMT3A) is an enzyme that catalyzes the transfer of methyl groups to specific CpG structures in DNA, a process called DNA methylation. The enzyme is encoded in humans by the DNMT3A gene.
The analysis highlights Research and Regions as prominent areas in the source structure around DNA (cytosine-5)-methyltransferase 3A.
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The extracted context around DNA (cytosine-5)-methyltransferase 3A shows recurring relationship patterns in the source. For example, DNA (cytosine-5)-methyltransferase 3A → ageing, C-5 methylation of cytosine, cellular response to amino acid stimulus, cellular response to ethanol, cellular response to hypoxia, chromatin binding, chromatin organization, chromosome, centromeric region, cytoplasm, DNA (cytosine-5-)-methyltransferase activity, DNA binding, DNA methylation, DNA methylation involved in embryo development, DNA methylation involved in gamete generation, DNA methylation on cytosine, DNA methylation-dependent heterochromatin assembly, DNA-binding transcription factor activity, RNA polymerase II-specific, DNA-methyltransferase activity, euchromatin, hepatocyte apoptotic process Another extracted example is DNA (cytosine-5)-methyltransferase 3A → ejaculatory duct, epithelium of urethra, female urethra, ganglionic eminence, genital tubercle, lamina propria of urethra, left ovary, male urethra, medullary collecting duct, muscle layer of urethra, muscle of thigh, oocyte, placenta, right ovary, Rostral migratory stream, Skeletal muscle tissue of biceps brachii, Skeletal muscle tissue of rectus abdominis, sural nerve, tail of embryo, ventricular zone. Use these groups to spot repeated connection types before inspecting the individual relationships.
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dnmt3a dna methylation protein gene dnmt3a2 de novo human accessory methyltransferase domain bp dnmt3b enzyme catalytic dnmt1 chr band function
TTTA extracted 124 structured relationships around DNA (cytosine-5)-methyltransferase 3A. Examples in this analysis include DNA (cytosine-5)-methyltransferase 3A → 2.1.1.37 → ↗ and DNA (cytosine-5)-methyltransferase 3A → Aliases → DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA methyltransferase 3 alpha, HESJAS. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| DNA (cytosine-5)-methyltransferase 3A | 2.1.1.37 | ↗ | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Aliases | DNMT3A, DNMT3A2, M.HsaIIIA, TBRS, DNA (cytosine-5-)-methyltransferase 3 alpha, DNA methyltransferase 3 alpha, HESJAS | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes4U7T, 4QBR, 4U7P, 4QBS, 3A1B, 3LLR, 4QBQ, 3SVM, 3A1A, 2QRV | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Band | 2p23.3 | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Band | 12|12 A1.1 | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | sural nerve | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | ganglionic eminence | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | ventricular zone | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | Skeletal muscle tissue of biceps brachii | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | oocyte | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | placenta | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | right ovary | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | muscle of thigh | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | Skeletal muscle tissue of rectus abdominis | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | left ovary | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | tail of embryo | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | male urethra | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | lamina propria of urethra | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | ejaculatory duct | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | genital tubercle | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | epithelium of urethra | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | female urethra | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | medullary collecting duct | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | muscle layer of urethra | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Bgee | Rostral migratory stream | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | BioGPS | More reference expression data | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Chr. | Chromosome 12 (mouse) | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| DNA (cytosine-5)-methyltransferase 3A | End | 25,342,590 bp | 1.00 | infobox |
The concept neighborhoods around DNA (cytosine-5)-methyltransferase 3A bring nearby vocabulary together. In this analysis, examples include Methylation, Human and Gene. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For DNA (cytosine-5)-methyltransferase 3A, one of the stronger structural bridges in this analysis connects DNA (cytosine-5)-methyltransferase 3A with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around DNA (cytosine-5)-methyltransferase 3A to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Research & Regions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — DNA (cytosine-5)-methyltransferase 3A · EN edition · Analysis: TopicsToTalkAbout
