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DDB2

DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene.

Function, Deficiency in humans & Structure

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Function

17 related topics

Deficiency in humans

7 related topics

Structure

2 related topics

Overview

2 related topics

Key facts & relationships

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Aliases
DDB2, DDBB, UV-XPE, damage specific DNA binding protein 2
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3EI4, 3I7L, 4E54, 4E5Z
Band
11p11.2 · 2|2 E1
Bgee
skin of abdomen · skin of leg · right uterine tube · right adrenal cortex · Descending thoracic aorta
BioGPS
More reference expression data
Chr.
Chromosome 11 (human) · Chromosome 2 (mouse)

Topics to explore

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Overview

Structure

Deficiency in humans

Function

Advanced semantic analysis

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Map overview Semantic statistics

DDB2

Nodes33
Edges32
Triples149
Avg. degree1.94
Density0.060606
Components1

How this topic connects Entity context

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DDB2

Top relations

Gene ontology · 32
DDB2 → cell junction, cellular response to DNA damage stimulus, Cul4-RING E3 ubiquitin ligase complex, Cul4B-RING E3 ubiquitin ligase complex, damaged DNA binding, DNA binding, DNA repair, global genome nucleotide-excision repair, histone H2A monoubiquitination, nucleoplasm, nucleotide-excision repair, nucleotide-excision repair, DNA damage recognition, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex assembly, nucleotide-excision repair, preincision complex stabilization, nucleus, post-translational protein modification
Bgee · 19
DDB2 → aortic valve, ascending aorta, ciliary body, Descending thoracic aorta, granulocyte, left adrenal cortex, left adrenal gland, medullary collecting duct, olfactory zone of nasal mucosa, otic vesicle, Paneth cell, primary oocyte, right adrenal cortex, right uterine tube, saccule, secondary oocyte, skin of abdomen, skin of leg, zygote
RNA expression pattern · 19
DDB2 → aortic valve, ascending aorta, ciliary body, Descending thoracic aorta, granulocyte, left adrenal cortex, left adrenal gland, medullary collecting duct, olfactory zone of nasal mucosa, otic vesicle, Paneth cell, primary oocyte, right adrenal cortex, right uterine tube, saccule, secondary oocyte, skin of abdomen, skin of leg, zygote
related to Chromatin remodeling · 15
DDB2 → Action, ADP, ALC1, CUL4A, DDB1, DNA, DNA-based, PARP1, PARylates, The, The PARP1, This, To, UV, UV-induced
related to Deficiency in humans · 14
DDB2 → DNA, If, Mutation, Patients, This, UV, XP, XPA, XPB, XPC, XPD, XPE, XPF, XPG
related to Structure · 10
DDB2 → As, DDB1, Rapić-Otrin, The C-terminal, The DDB2, The WD40, Together, UV-damaged DNA, UV-DDB, WD40
related to Binding to damaged DNA · 9
DDB2 → As, DDB, DDB1, DNA, The, The DDB2, UV, Wittschieben, XP-E
related to Other functions · 8
DDB2 → Decreased, DNA, H3, H3K56Ac, In, UV-induced DNA, Zhu, Zou
Band · 2
DDB2 → 11p11.2, 2|2 E1
Chr. · 2
DDB2 → Chromosome 11 (human), Chromosome 2 (mouse)

Important terminology Word statistics

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Important terminology

dna protein gene chromatin human bp binding repair chr band damage chromosome et al 11 complex uv damaged ddb1 heterodimer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DDB2AliasesDDB2, DDBB, UV-XPE, damage specific DNA binding protein 21.00infobox
DDB2Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3EI4, 3I7L, 4E54, 4E5Z1.00infobox
DDB2Band11p11.21.00infobox
DDB2Band2|2 E11.00infobox
DDB2Bgeeskin of abdomen1.00infobox
DDB2Bgeeskin of leg1.00infobox
DDB2Bgeeright uterine tube1.00infobox
DDB2Bgeeright adrenal cortex1.00infobox
DDB2BgeeDescending thoracic aorta1.00infobox
DDB2Bgeeolfactory zone of nasal mucosa1.00infobox
DDB2Bgeegranulocyte1.00infobox
DDB2Bgeeleft adrenal gland1.00infobox
DDB2Bgeeascending aorta1.00infobox
DDB2Bgeeleft adrenal cortex1.00infobox
DDB2BgeePaneth cell1.00infobox
DDB2Bgeesecondary oocyte1.00infobox
DDB2Bgeezygote1.00infobox
DDB2Bgeemedullary collecting duct1.00infobox
DDB2Bgeeprimary oocyte1.00infobox
DDB2Bgeesaccule1.00infobox
DDB2Bgeeaortic valve1.00infobox
DDB2Bgeeotic vesicle1.00infobox
DDB2Bgeeciliary body1.00infobox
DDB2BioGPSMore reference expression data1.00infobox
DDB2Chr.Chromosome 11 (human)1.00infobox
DDB2Chr.Chromosome 2 (mouse)1.00infobox
DDB2DatabasesNCBI: entry; OMA: entry1.00infobox
DDB2End47,239,217 bp1.00infobox
DDB2End91,067,327 bp1.00infobox
DDB2EnsemblENSG000001345741.00infobox

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