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CHD1L

Chromodomain-helicase-DNA-binding protein 1-like (ALC1) is an enzyme that in humans is encoded by the CHD1L gene. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription. The ALC1 comprises ATPase domain and macro domain. On the basis of homology within the ATPase domain, ALC1…

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Aliases
CHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like
Band
1q21.1 · 3|3 F2.2
Bgee
gonad · C1 segment · right hemisphere of cerebellum · right lobe of liver · anterior pituitary
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry

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CHD1L

Nodes20
Edges19
Triples115
Avg. degree1.9
Density0.1
Components1

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CHD1L

Top relations

Gene ontology · 22
CHD1L → ATP binding, ATPase activity, cellular response to DNA damage stimulus, chromatin remodeling, cytosol, DNA duplex unwinding, DNA helicase activity, DNA repair, global genome nucleotide-excision repair, helicase activity, hydrolase activity, nucleoplasm, nucleotide binding, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex assembly, nucleotide-excision repair, preincision complex stabilization, nucleus
Bgee · 20
CHD1L → anterior pituitary, ascending aorta, C1 segment, Descending thoracic aorta, gonad, Gonadal ridge, granulocyte, mucosa of transverse colon, otic placode, otic vesicle, Paneth cell, primitive streak, right hemisphere of cerebellum, right lobe of liver, saccule, seminiferous tubule, spermatid, spermatocyte, spleen, transitional epithelium of urinary bladder
RNA expression pattern · 20
CHD1L → anterior pituitary, ascending aorta, C1 segment, Descending thoracic aorta, gonad, Gonadal ridge, granulocyte, mucosa of transverse colon, otic placode, otic vesicle, Paneth cell, primitive streak, right hemisphere of cerebellum, right lobe of liver, saccule, seminiferous tubule, spermatid, spermatocyte, spleen, transitional epithelium of urinary bladder
related to In DNA repair · 15
CHD1L → About, ALC1, Chromatin, DNA, MRE11, N-terminal, Next, PAR, PARP1, PARylates, R611, The, This, To, UV-damaged
related to In development · 12
CHD1L → Akt, CHD1L's, DNA, EMT, It, METP2, Notably, PAR, PARP1/PARylation, PARylated-PARP1, TCF4, The CHD1L
related to Related gene problems · 4
CHD1L → DNA, The, Werner, With
Band · 2
CHD1L → 1q21.1, 3|3 F2.2
Chr. · 2
CHD1L → Chromosome 1 (human), Chromosome 3 (mouse)
End · 2
CHD1L → 147,295,765 bp, 97,517,519 bp
related to External links · 2
CHD1L → Human CHD1L, UCSC Genome Browser

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Important terminology

dna chromatin alc1 repair gene bp human chr band protein chromosome helicase damage remodeling process location atpase parp1 within domain

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CHD1LAliasesCHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like1.00infobox
CHD1LBand1q21.11.00infobox
CHD1LBand3|3 F2.21.00infobox
CHD1LBgeegonad1.00infobox
CHD1LBgeeC1 segment1.00infobox
CHD1LBgeeright hemisphere of cerebellum1.00infobox
CHD1LBgeeright lobe of liver1.00infobox
CHD1LBgeeanterior pituitary1.00infobox
CHD1LBgeeascending aorta1.00infobox
CHD1LBgeemucosa of transverse colon1.00infobox
CHD1LBgeegranulocyte1.00infobox
CHD1LBgeespleen1.00infobox
CHD1LBgeeDescending thoracic aorta1.00infobox
CHD1LBgeesaccule1.00infobox
CHD1LBgeeotic placode1.00infobox
CHD1LBgeetransitional epithelium of urinary bladder1.00infobox
CHD1LBgeeseminiferous tubule1.00infobox
CHD1LBgeeotic vesicle1.00infobox
CHD1LBgeespermatocyte1.00infobox
CHD1LBgeespermatid1.00infobox
CHD1LBgeeprimitive streak1.00infobox
CHD1LBgeePaneth cell1.00infobox
CHD1LBgeeGonadal ridge1.00infobox
CHD1LBioGPSMore reference expression data1.00infobox
CHD1LChr.Chromosome 1 (human)1.00infobox
CHD1LChr.Chromosome 3 (mouse)1.00infobox
CHD1LDatabasesNCBI: entry; OMA: entry1.00infobox
CHD1LEnd147,295,765 bp1.00infobox
CHD1LEnd97,517,519 bp1.00infobox
CHD1LEnsemblENSG000001317781.00infobox

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