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CHD1L: Products, Function & Related gene problems
Chromodomain-helicase-DNA-binding protein 1-like (ALC1) is an enzyme that in humans is encoded by the CHD1L gene. It has been implicated in chromatin remodeling and DNA relaxation process required for DNA replication, repair and transcription. The ALC1 comprises ATPase domain and macro domain. On the basis of homology within the ATPase domain, ALC1…
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CHD1L topic overview
The analysis highlights Products, Function and Related gene problems as prominent areas in the source structure around CHD1L.
Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
115
Concept neighborhoods
12
Bridge connections
19
What this topic covers Research coverage
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Function · 11 topics
Related gene problems · 3 topics
Overview · 2 topics
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
Key facts & relationships
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Aliases
CHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like
Band
1q21.1 · 3|3 F2.2
Bgee
gonad · C1 segment · right hemisphere of cerebellum · right lobe of liver · anterior pituitary
BioGPS
More reference expression data
Chr.
Chromosome 1 (human) · Chromosome 3 (mouse)
Databases
NCBI: entry; OMA: entry
Explore all related topics Closing gaps
A structured outline of related entities, concepts and subtopics. Open any item to build a new map centered on it.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
How CHD1L connects Entity context
Entity context groups extracted connections by relationship type. Counts show recurrence in the analyzed source; the examples are research signals, not claims about importance.
The extracted context around CHD1L shows recurring relationship patterns in the source. For example, CHD1L → ATP binding, ATPase activity, cellular response to DNA damage stimulus, chromatin remodeling, cytosol, DNA duplex unwinding, DNA helicase activity, DNA repair, global genome nucleotide-excision repair, helicase activity, hydrolase activity, nucleoplasm, nucleotide binding, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex assembly, nucleotide-excision repair, preincision complex stabilization, nucleus Another extracted example is CHD1L → anterior pituitary, ascending aorta, C1 segment, Descending thoracic aorta, gonad, Gonadal ridge, granulocyte, mucosa of transverse colon, otic placode, otic vesicle, Paneth cell, primitive streak, right hemisphere of cerebellum, right lobe of liver, saccule, seminiferous tubule, spermatid, spermatocyte, spleen, transitional epithelium of urinary bladder. Use these groups to spot repeated connection types before inspecting the individual relationships.
CHD1L
Top relations
Gene ontology· 22
CHD1L → ATP binding, ATPase activity, cellular response to DNA damage stimulus, chromatin remodeling, cytosol, DNA duplex unwinding, DNA helicase activity, DNA repair, global genome nucleotide-excision repair, helicase activity, hydrolase activity, nucleoplasm, nucleotide binding, nucleotide-excision repair, DNA duplex unwinding, nucleotide-excision repair, DNA incision, nucleotide-excision repair, DNA incision, 3'-to lesion, nucleotide-excision repair, DNA incision, 5'-to lesion, nucleotide-excision repair, preincision complex assembly, nucleotide-excision repair, preincision complex stabilization, nucleus
Bgee· 20
CHD1L → anterior pituitary, ascending aorta, C1 segment, Descending thoracic aorta, gonad, Gonadal ridge, granulocyte, mucosa of transverse colon, otic placode, otic vesicle, Paneth cell, primitive streak, right hemisphere of cerebellum, right lobe of liver, saccule, seminiferous tubule, spermatid, spermatocyte, spleen, transitional epithelium of urinary bladder
RNA expression pattern· 20
CHD1L → anterior pituitary, ascending aorta, C1 segment, Descending thoracic aorta, gonad, Gonadal ridge, granulocyte, mucosa of transverse colon, otic placode, otic vesicle, Paneth cell, primitive streak, right hemisphere of cerebellum, right lobe of liver, saccule, seminiferous tubule, spermatid, spermatocyte, spleen, transitional epithelium of urinary bladder
Relationships are represented as Subject → Predicate → Object triples. Confidence describes extraction strength, not the real-world importance of a relationship; lower-confidence rows may be contextual rather than explicit.
TTTA extracted 115 structured relationships around CHD1L. Examples in this analysis include CHD1L → Aliases → CHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like and CHD1L → Band → 1q21.1. The table shows each extracted connection, where it came from and its confidence.
Subject
Predicate
Object
Confidence
Src
CHD1L
Aliases
CHD1L, ALC1, CHDL, chromodomain helicase DNA binding protein 1-like, chromodomain helicase DNA binding protein 1 like
1.00
infobox
CHD1L
Band
1q21.1
1.00
infobox
CHD1L
Band
3|3 F2.2
1.00
infobox
CHD1L
Bgee
gonad
1.00
infobox
CHD1L
Bgee
C1 segment
1.00
infobox
CHD1L
Bgee
right hemisphere of cerebellum
1.00
infobox
CHD1L
Bgee
right lobe of liver
1.00
infobox
CHD1L
Bgee
anterior pituitary
1.00
infobox
CHD1L
Bgee
ascending aorta
1.00
infobox
CHD1L
Bgee
mucosa of transverse colon
1.00
infobox
CHD1L
Bgee
granulocyte
1.00
infobox
CHD1L
Bgee
spleen
1.00
infobox
CHD1L
Bgee
Descending thoracic aorta
1.00
infobox
CHD1L
Bgee
saccule
1.00
infobox
CHD1L
Bgee
otic placode
1.00
infobox
CHD1L
Bgee
transitional epithelium of urinary bladder
1.00
infobox
CHD1L
Bgee
seminiferous tubule
1.00
infobox
CHD1L
Bgee
otic vesicle
1.00
infobox
CHD1L
Bgee
spermatocyte
1.00
infobox
CHD1L
Bgee
spermatid
1.00
infobox
CHD1L
Bgee
primitive streak
1.00
infobox
CHD1L
Bgee
Paneth cell
1.00
infobox
CHD1L
Bgee
Gonadal ridge
1.00
infobox
CHD1L
BioGPS
More reference expression data
1.00
infobox
CHD1L
Chr.
Chromosome 1 (human)
1.00
infobox
CHD1L
Chr.
Chromosome 3 (mouse)
1.00
infobox
CHD1L
Databases
NCBI: entry; OMA: entry
1.00
infobox
CHD1L
End
147,295,765 bp
1.00
infobox
CHD1L
End
97,517,519 bp
1.00
infobox
CHD1L
Ensembl
ENSG00000131778
1.00
infobox
No triples extracted yet.
Related concept clusters Concept neighborhoods
Concept neighborhoods group terms that sit near one another in the extracted graph. They are useful for discovering adjacent language and context, but proximity does not by itself imply a factual relationship.
The concept neighborhoods around CHD1L bring nearby vocabulary together. In this analysis, examples include Chromatin, Gene and Protein. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
CHD1L
Chromatin
Gene
Protein
Helicase
Repair
Location
Parp1
Dna
Human
Binding
Function
Development
chd1l
Chromatin
Gene
Protein
Helicase
Repair
Location
Parp1
Dna
Human
Binding
Function
Development
chromatin remodeling
Dna
Repair
Damage
Protein
Relaxation
Remodeling
Parp1
Process
Binding
End
F2
Function
chromatin
Dna
Repair
Damage
Relaxation
Remodeling
Parp1
Process
Required
Occurs
Seconds
Protein
Binding
gene
Location
Human
Helicase
Chromosome
Bp
Chr
Protein
Binding
End
F2
Function
Mouse
related gene problems
Location
Human
Helicase
Chromosome
Bp
Chr
Protein
Binding
End
F2
Function
Mouse
nucleotide excision repair
Protein
Binding
Function
Required
Helicase
Chromosome
Location
Bp
Chr
Damage
Human
External
function
Binding
Helicase
Chromosome
External
Location
Bp
Chr
Gene
Human
Protein
End
F2
Connections between topic areas Semantic bridges
Semantic bridges connect parts of the graph that would otherwise be more separate. A bridge is a structural signal in this analysis, not a claim that the two topic areas are equivalent.
For CHD1L, one of the stronger structural bridges in this analysis connects CHD1L with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
Number of nodes, edges, triples, density and central hubs. Use it to gauge the size and connectivity of the map.
CHD1L
Nodes20
Edges19
Triples115
Avg. degree1.9
Density0.1
Components1
Source & methodology
TTTA analyzes the structure around CHD1L to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Products, Function & Related gene problems, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — CHD1L · EN edition · Analysis: TopicsToTalkAbout
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