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Statin

Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower the concentration of cholesterol in the blood. They are typically prescribed to people who are at high risk of cardiovascular disease.

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ATC code
C10AA
Biological target
HMG-CoA reductase
Drugs.com
Drug Classes
MeSH
D019161
Synonyms
HMG-CoA reductase inhibitors
Use
High cholesterol

Topics to explore

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Overview

Medical uses

Adverse effects

Other effects

Mechanism of action

Statin medications

History

Research

Advanced semantic analysis

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Map overview Semantic statistics

Statin

Nodes199
Edges198
Triples174
Avg. degree1.99
Density0.01005
Components1

How this topic connects Entity context

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Statin

Top relations

has effect · 34
Statin → Additionally, Alzheimer's, Americas, Another, As, Asia, Austrian, Circulatory Health, Cochrane, CoQ10, Effectiveness Research, Health Protection Study, HMG-CoA, HPS, Improve, International Centre, London, Lung Institute, Multiple, National Heart
has prevention · 20
Statin → ACC/AHA Pooled Cohort, Cochrane, Defining, For, HDL-cholesterol, However, HPS, In, LDL, Most, No, On, Pre-existing, PROSPER, Risk, Task Force, They, Two, United States Preventive Services, USPSTF
related to history · 17
Statin → Akira Endo, Cholesterol, Coronary Primary Prevention Trial, Daniel Steinberg, Endo, HMG-CoA, In, Japanese, ML-236B, Penicillium, Research, Sankyo, Scientists, The, There, This, Treatment
related to Diabetes · 8
Statin → GLUT1, Higher, HMGCoAR, However, One, Statins, The, Use
related to Drug interactions · 8
Statin → Combining, Consumption, CYP3A4, Furanocoumarins, Monitoring, P450, The, This
related to Decreasing of specific protein prenylation · 7
Statin → HMG-CoA, In, Inhibition, LDL, Rho-associated, RhoA, Statins
related to External links · 7
Statin → April, Brody JE, Cons, Pros, Statins, The New York Times, Weighing
related to Inhibiting cholesterol synthesis · 7
Statin → By, Cholesterol, HMG-CoA, LDL, Studies, This, When
related to Mechanism of action · 7
Statin → Aspergillus, Because, HMG-CoA, Penicillium, Statins, These, This
related to Muscles · 7
Statin → In, Muscle, RCT, RCTs, The, These, This

Important terminology Word statistics

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Important terminology

statins risk cholesterol disease people cardiovascular simvastatin ldl muscle effects heart hmg-coa atorvastatin diabetes found lovastatin adverse use high pravastatin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
StatinATC codeC10AA1.00infobox
StatinBiological targetHMG-CoA reductase1.00infobox
StatinDrugs.comDrug Classes1.00infobox
StatinMeSHD0191611.00infobox
StatinSynonymsHMG-CoA reductase inhibitors1.00infobox
StatinUseHigh cholesterol1.00infobox
family historyinstance offactors0.80text
coronary calcium scoreinstance offactors0.80text
ankle-brachial indexinstance offactors0.80text
and an inflammation testinstance offactors0.80text
Steven Einstance ofcritics0.80text
rhabdomyolysisinstance ofas long as people continue to take them.Serious muscle problems0.80text

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    Min side: 3
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