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Circular RNA

In molecular biology, circular ribonucleic acid (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5' ends normally present in an RNA molecule have been joined together. This feature confers numerous properties to circular RNA, many of which have only recently…

Characters, Characteristics of circular RNA & Plausible functions

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Characteristics of circular RNA

DCCSryANRILETS-1P450
17 related topics

Plausible functions

Domains of lifeArchaeaParietal lobeParalogousHIPK2
19 related topics

Overview

Molecular biologyRNACovalently3' and 5' endsProtein-coding
53 related topics

Splicing

BacteriaEukaryoticIntronMessenger RNAExons
7 related topics

Topics to explore

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Overview

Splicing

Impact of RNA editing

Characteristics of circular RNA

Plausible functions

Disease

Immune response

Myogenesis regulation

Viroids

Origin

Advanced semantic analysis

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Map overview Semantic statistics

Circular RNA

Nodes120
Edges119
Triples104
Avg. degree1.98
Density0.016667
Components1

How this topic connects Entity context

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Circular RNA

Top relations

related to Disease · 20
Circular RNA → ANRIL, As, Circular ANRIL, Circular RNAs, Expression, For, Further, Given, HIV, HIV-1, If, INK4/ARF, It, Parkinson's, Perhaps CiRS-7's, RNA, SRSF1, SRSF1's, Subsequently, Vpr
related to CDR1as/CiRS-7 as a miR-7 sponge · 14
Circular RNA → AGO, Argonaut, Argonaute, CDR1as/CiRS-7, Certain, Detail, Family, HITS-CLIP, MicroRNAs, Protein, RNA, RNAs, They, Two
related to Early discoveries · 10
Circular RNA → CircRNA, DCC, Early, ETS-1, P450, RNA ANRIL, RNAs, Shbg, Sry, These
related to Evolutionary conservation of circularization mechanisms and signals · 9
Circular RNA → After, Archaea, By, CircRNAs, Danan, However, In, RNA, RNase
related to Immune response · 8
Circular RNA → After, CD8, IL-1β, IL-6, Plasma, RNA, TNFa, Treatment
related to Length · 7
Circular RNA → Alu, By, Compared, During, Each, Introns, RNAs
related to Location in the cell · 7
Circular RNA → Because, CiRS-7/CDR1as, However, In, It, RNA, RNAs
related to Myogenesis regulation · 7
Circular RNA → CaMKIId, CircSVIL, HDAC4, MEF2A, SRF, Wnt, Wnt5a
related to Origin · 5
Circular RNA → Early, However, It, RNA, Thus
related to Classes · 1
Circular RNA → Circular RNAs

Important terminology Word statistics

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Important terminology

rna circular circrnas circrna found rnas exons genes protein disease expression human expressed cell also linear alu role gene cancer

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
cancer..mw-parser-output .toclimit-2 .toclevel-1 ulinstance ofCircular RNA has been linked to some diseases0.80text
.mw-parser-output .toclimit-3 .toclevel-2 ulinstance ofCircular RNA has been linked to some diseases0.80text
.mw-parser-output .toclimit-4 .toclevel-3 ulinstance ofCircular RNA has been linked to some diseases0.80text
.mw-parser-output .toclimit-5 .toclevel-4 ulinstance ofCircular RNA has been linked to some diseases0.80text
.mw-parser-output .toclimit-6 .toclevel-5 ulinstance ofCircular RNA has been linked to some diseases0.80text
.mw-parser-output .toclimit-7 .toclevel-6 ulinstance ofCircular RNA has been linked to some diseases0.80text
circ-ITCH which regulates lung cancer associated with oncogenic sponges miR7instance ofsome CircRNAs show positive effects0.80text
miR214instance ofsome CircRNAs show positive effects0.80text
overexpression of circ-ITCH inhibits cell proliferation in lung cancerinstance ofsome CircRNAs show positive effects0.80text
Epstein Barr virusinstance ofSome viruses0.80text
human papillomavirus can encode circular RNAs such asinstance ofSome viruses0.80text
circRBFOX2instance ofMyogenesis regulationCircular RNA plays an important role in myogenesis mechanisms0.80text

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