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In molecular biology, circular ribonucleic acid (or circRNA) is a type of single-stranded RNA which, unlike linear RNA, forms a covalently closed continuous loop. In circular RNA, the 3' and 5' ends normally present in an RNA molecule have been joined together. This feature confers numerous properties to circular RNA, many of which have only recently…
The analysis highlights Characters, Characteristics of circular RNA and Plausible functions as prominent areas in the source structure around Circular RNA.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
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The extracted context around Circular RNA shows recurring relationship patterns in the source. For example, Circular RNA → ANRIL, Circular ANRIL, Circular RNAs, Expression, Given, HIV, HIV-1, INK4/ARF, Parkinson's, Perhaps CiRS-7's, RNA, SRSF1, SRSF1's, Subsequently, Vpr Another extracted example is Circular RNA → AGO, Argonaut, Argonaute, CDR1as/CiRS-7, Certain, Detail, Family, HITS-CLIP, MicroRNAs, Protein, RNA, RNAs, Two. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
rna circular circrnas circrna found rnas exons genes protein disease expression human expressed cell also linear alu role gene cancer
TTTA extracted 75 structured relationships around Circular RNA. Examples in this analysis include circ-ITCH which regulates lung cancer associated with oncogenic sponges miR7 → instance of → some CircRNAs show positive effects and Epstein Barr virus → instance of → Some viruses. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| circ-ITCH which regulates lung cancer associated with oncogenic sponges miR7 | instance of | some CircRNAs show positive effects | 0.80 | text |
| miR214 | instance of | some CircRNAs show positive effects | 0.80 | text |
| overexpression of circ-ITCH inhibits cell proliferation in lung cancer | instance of | some CircRNAs show positive effects | 0.80 | text |
| Epstein Barr virus | instance of | Some viruses | 0.80 | text |
| human papillomavirus can encode circular RNAs such as | instance of | Some viruses | 0.80 | text |
| circRBFOX2 | instance of | Myogenesis regulationCircular RNA plays an important role in myogenesis mechanisms | 0.80 | text |
| circLMO7 acts as a negative regulator | instance of | Myogenesis regulationCircular RNA plays an important role in myogenesis mechanisms | 0.80 | text |
| CircSVIL acts as a positive regulator. circRBFOX2 regulates miR-206 expression | instance of | Myogenesis regulationCircular RNA plays an important role in myogenesis mechanisms | 0.80 | text |
| induces myoblast proliferation in a negative effect on the myogenesis process. circLMO7 is involved in overexpression of HDAC4 | instance of | Myogenesis regulationCircular RNA plays an important role in myogenesis mechanisms | 0.80 | text |
| downregulates MEF2A expression by upregulating miR-378a-3p leading to myoblast differentiation | instance of | Myogenesis regulationCircular RNA plays an important role in myogenesis mechanisms | 0.80 | text |
| Circular RNA | related to CDR1as/CiRS-7 as a miR-7 sponge | RNAs | 0.60 | section |
| Circular RNA | related to CDR1as/CiRS-7 as a miR-7 sponge | MicroRNAs | 0.60 | section |
The concept neighborhoods around Circular RNA bring nearby vocabulary together. In this analysis, examples include Rna, Rnas and Found. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For Circular RNA, one of the stronger structural bridges in this analysis connects Circular RNA with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around Circular RNA to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Characters, Characteristics of circular RNA & Plausible functions, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — Circular RNA · EN edition · Analysis: TopicsToTalkAbout