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DSCAM

DSCAM and Dscam are both abbreviations for Down syndrome cell adhesion molecule. In humans, DSCAM refers to a gene that encodes one of several protein isoforms.

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Aliases
DSCAM, CHD2-42, CHD2-52, CHD2, DS cell adhesion molecule
Band
21q22.2 · 16 C4|16 57.02 cM
Bgee
lateral nuclear group of thalamus · buccal mucosa cell · entorhinal cortex · external globus pallidus · postcentral gyrus
BioGPS
n/a
Chr.
Chromosome 21 (human) · Chromosome 16 (mouse)
Databases
NCBI: entry; OMA: entry

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Overview

History/discovery

Gene

Functions

Interactions

Clinical significance

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Map overview Semantic statistics

DSCAM

Nodes78
Edges77
Triples156
Avg. degree1.97
Density0.025641
Components1

How this topic connects Entity context

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DSCAM

Top relations

Gene ontology · 31
DSCAM → axon, axon guidance, camera-type eye photoreceptor cell differentiation, cell adhesion, cell junction, cell projection, cell-cell adhesion mediator activity, dendrite, dendrite morphogenesis, dendrite self-avoidance, extracellular region, growth cone, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, locomotory behavior, membrane, negative regulation of cell adhesion, nervous system development, netrin receptor binding
related to Clinical significance · 25
DSCAM → Cajal, CHD, COL6A2, Down, Drosophila, DS, DSCAML1, DSCAMs, Epicanthus, Further, Given, H9c2, However, Ig-CAMs, LIS1, Nonetheless, Reelin, Retzius, Strabismus, Telecanthus
Bgee · 20
DSCAM → Brodmann area 23, Brodmann area 46, buccal mucosa cell, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, external globus pallidus, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, nucleus of stria terminalis, pars reticulata, postcentral gyrus, substantia nigra, superior frontal gyrus, ventromedial nucleus
RNA expression pattern · 20
DSCAM → Brodmann area 23, Brodmann area 46, buccal mucosa cell, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, external globus pallidus, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, nucleus of stria terminalis, pars reticulata, postcentral gyrus, substantia nigra, superior frontal gyrus, ventromedial nucleus
related to Gene · 12
DSCAM → Another DSCAM-like, Diverse, Down, DS, DSCAML1, Gilles, Ig, It, Jacobsen, The DSCAM, Tourette, When
related to Immunity · 9
DSCAM → AgDscam, Anopheles, In, Instead, Invertebrates, Plasmodium, PRRs, RNAi, The
related to Interactions · 9
DSCAM → Biochemical, Drosophila Dscam, Dscam/DSCAM, DSCAML1, DSCAML1s, Due, Many Ig, This, Vertebrate DSCAMs
related to history · 6
DSCAM → CAMs, Down, Ig, Since, The, The DSCAM
related to Regulation of synaptogenesis · 3
DSCAM → Cell, Self-avoidance, These
Band · 2
DSCAM → 16 C4|16 57.02 cM, 21q22.2

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Important terminology

gene cell isoforms development drosophila expression ds system role syndrome human adhesion nervous band chromosome 21 bp self-avoidance dscam1 molecules

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
DSCAMAliasesDSCAM, CHD2-42, CHD2-52, CHD2, DS cell adhesion molecule1.00infobox
DSCAMBand21q22.21.00infobox
DSCAMBand16 C4|16 57.02 cM1.00infobox
DSCAMBgeelateral nuclear group of thalamus1.00infobox
DSCAMBgeebuccal mucosa cell1.00infobox
DSCAMBgeeentorhinal cortex1.00infobox
DSCAMBgeeexternal globus pallidus1.00infobox
DSCAMBgeepostcentral gyrus1.00infobox
DSCAMBgeeBrodmann area 461.00infobox
DSCAMBgeesuperior frontal gyrus1.00infobox
DSCAMBgeeBrodmann area 231.00infobox
DSCAMBgeepars reticulata1.00infobox
DSCAMBgeeinternal globus pallidus1.00infobox
DSCAMBgeelumbar subsegment of spinal cord1.00infobox
DSCAMBgeesubstantia nigra1.00infobox
DSCAMBgeedentate gyrus of hippocampal formation granule cell1.00infobox
DSCAMBgeemedial geniculate nucleus1.00infobox
DSCAMBgeelateral geniculate nucleus1.00infobox
DSCAMBgeenucleus of stria terminalis1.00infobox
DSCAMBgeelateral septal nucleus1.00infobox
DSCAMBgeeventromedial nucleus1.00infobox
DSCAMBgeecentral gray substance of midbrain1.00infobox
DSCAMBgeemedial dorsal nucleus1.00infobox
DSCAMBioGPSn/a1.00infobox
DSCAMChr.Chromosome 21 (human)1.00infobox
DSCAMChr.Chromosome 16 (mouse)1.00infobox
DSCAMDatabasesNCBI: entry; OMA: entry1.00infobox
DSCAMEnd40,847,158 bp1.00infobox
DSCAMEnd97,170,752 bp1.00infobox
DSCAMEnsemblENSG000001715871.00infobox

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