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DSCAM: History & Standards

DSCAM and Dscam are both abbreviations for Down syndrome cell adhesion molecule. In humans, DSCAM refers to a gene that encodes one of several protein isoforms.

Language: English [EN]
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DSCAM topic overview

The analysis highlights History and Standards as prominent areas in the source structure around DSCAM.

Related topics
71
Source areas
6
Connected nodes
77
Extracted relationships
156
Concept neighborhoods
13
Bridge connections
77

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Gene · 20 topics
Clinical significance · 19 topics
Functions · 16 topics
Overview · 9 topics
History/discovery · 6 topics
Interactions · 1 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
DSCAM, CHD2-42, CHD2-52, CHD2, DS cell adhesion molecule
Band
21q22.2 · 16 C4|16 57.02 cM
Bgee
lateral nuclear group of thalamus · buccal mucosa cell · entorhinal cortex · external globus pallidus · postcentral gyrus
BioGPS
n/a
Chr.
Chromosome 21 (human) · Chromosome 16 (mouse)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

History/discovery

Gene

Functions

Interactions

Clinical significance

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How DSCAM connects Entity context

The extracted context around DSCAM shows recurring relationship patterns in the source. For example, DSCAM → axon, axon guidance, camera-type eye photoreceptor cell differentiation, cell adhesion, cell junction, cell projection, cell-cell adhesion mediator activity, dendrite, dendrite morphogenesis, dendrite self-avoidance, extracellular region, growth cone, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, locomotory behavior, membrane, negative regulation of cell adhesion, nervous system development, netrin receptor binding Another extracted example is DSCAM → Cajal, CHD, COL6A2, Down, Drosophila, DS, DSCAML1, DSCAMs, Epicanthus, Further, Given, H9c2, However, Ig-CAMs, LIS1, Nonetheless, Reelin, Retzius, Strabismus, Telecanthus. Use these groups to spot repeated connection types before inspecting the individual relationships.

DSCAM

Top relations

Gene ontology · 31
DSCAM → axon, axon guidance, camera-type eye photoreceptor cell differentiation, cell adhesion, cell junction, cell projection, cell-cell adhesion mediator activity, dendrite, dendrite morphogenesis, dendrite self-avoidance, extracellular region, growth cone, homophilic cell adhesion via plasma membrane adhesion molecules, integral component of membrane, integral component of plasma membrane, locomotory behavior, membrane, negative regulation of cell adhesion, nervous system development, netrin receptor binding
related to Clinical significance · 25
DSCAM → Cajal, CHD, COL6A2, Down, Drosophila, DS, DSCAML1, DSCAMs, Epicanthus, Further, Given, H9c2, However, Ig-CAMs, LIS1, Nonetheless, Reelin, Retzius, Strabismus, Telecanthus
Bgee · 20
DSCAM → Brodmann area 23, Brodmann area 46, buccal mucosa cell, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, external globus pallidus, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, nucleus of stria terminalis, pars reticulata, postcentral gyrus, substantia nigra, superior frontal gyrus, ventromedial nucleus
RNA expression pattern · 20
DSCAM → Brodmann area 23, Brodmann area 46, buccal mucosa cell, central gray substance of midbrain, dentate gyrus of hippocampal formation granule cell, entorhinal cortex, external globus pallidus, internal globus pallidus, lateral geniculate nucleus, lateral nuclear group of thalamus, lateral septal nucleus, lumbar subsegment of spinal cord, medial dorsal nucleus, medial geniculate nucleus, nucleus of stria terminalis, pars reticulata, postcentral gyrus, substantia nigra, superior frontal gyrus, ventromedial nucleus
related to Gene · 12
DSCAM → Another DSCAM-like, Diverse, Down, DS, DSCAML1, Gilles, Ig, It, Jacobsen, The DSCAM, Tourette, When
related to Immunity · 9
DSCAM → AgDscam, Anopheles, In, Instead, Invertebrates, Plasmodium, PRRs, RNAi, The
related to Interactions · 9
DSCAM → Biochemical, Drosophila Dscam, Dscam/DSCAM, DSCAML1, DSCAML1s, Due, Many Ig, This, Vertebrate DSCAMs
related to history · 6
DSCAM → CAMs, Down, Ig, Since, The, The DSCAM
related to Regulation of synaptogenesis · 3
DSCAM → Cell, Self-avoidance, These
Band · 2
DSCAM → 16 C4|16 57.02 cM, 21q22.2

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

gene cell isoforms development drosophila expression ds system role syndrome human adhesion nervous band chromosome 21 bp self-avoidance dscam1 molecules

DSCAM relationships Subject–Predicate–Object triples

TTTA extracted 156 structured relationships around DSCAM. Examples in this analysis include DSCAM → Aliases → DSCAM, CHD2-42, CHD2-52, CHD2, DS cell adhesion molecule and DSCAM → Band → 21q22.2. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
DSCAMAliasesDSCAM, CHD2-42, CHD2-52, CHD2, DS cell adhesion molecule1.00infobox
DSCAMBand21q22.21.00infobox
DSCAMBand16 C4|16 57.02 cM1.00infobox
DSCAMBgeelateral nuclear group of thalamus1.00infobox
DSCAMBgeebuccal mucosa cell1.00infobox
DSCAMBgeeentorhinal cortex1.00infobox
DSCAMBgeeexternal globus pallidus1.00infobox
DSCAMBgeepostcentral gyrus1.00infobox
DSCAMBgeeBrodmann area 461.00infobox
DSCAMBgeesuperior frontal gyrus1.00infobox
DSCAMBgeeBrodmann area 231.00infobox
DSCAMBgeepars reticulata1.00infobox
DSCAMBgeeinternal globus pallidus1.00infobox
DSCAMBgeelumbar subsegment of spinal cord1.00infobox
DSCAMBgeesubstantia nigra1.00infobox
DSCAMBgeedentate gyrus of hippocampal formation granule cell1.00infobox
DSCAMBgeemedial geniculate nucleus1.00infobox
DSCAMBgeelateral geniculate nucleus1.00infobox
DSCAMBgeenucleus of stria terminalis1.00infobox
DSCAMBgeelateral septal nucleus1.00infobox
DSCAMBgeeventromedial nucleus1.00infobox
DSCAMBgeecentral gray substance of midbrain1.00infobox
DSCAMBgeemedial dorsal nucleus1.00infobox
DSCAMBioGPSn/a1.00infobox
DSCAMChr.Chromosome 21 (human)1.00infobox
DSCAMChr.Chromosome 16 (mouse)1.00infobox
DSCAMDatabasesNCBI: entry; OMA: entry1.00infobox
DSCAMEnd40,847,158 bp1.00infobox
DSCAMEnd97,170,752 bp1.00infobox
DSCAMEnsemblENSG000001715871.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around DSCAM bring nearby vocabulary together. In this analysis, examples include Cell, Gene and Expression. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • DSCAM
    • Cell
    • Gene
    • Expression
    • Role
    • Adhesion
    • Ds
    • Development
    • Drosophila
    • Isoforms
    • Protein
    • Also
    • Proteins
  • dscam
    • Cell
    • Gene
    • Expression
    • Role
    • Adhesion
    • Ds
    • Development
    • Drosophila
    • Isoforms
    • Protein
    • Also
    • Proteins
  • gene
    • Chromosome
    • Human
    • Bp
    • Chr
    • Band
    • Dscam1
    • Ds
    • Isoforms
    • Protein
    • Pattern
    • Homophilic
    • Nervous
  • human chromosome band 21q22
    • Band
    • Chromosome
    • Bp
    • Chr
    • Human
    • Gene
    • Syndrome
    • Role
    • Expressed
    • Protein
    • Molecule
    • Pattern
  • cell adhesion molecules
    • Adhesion
    • Cell
    • Molecule
    • Molecules
    • Syndrome
    • Protein
    • Neural
    • Bp
    • Chr
    • Dscam
    • Dscam1
    • Chromosome
  • protein isoforms
    • Melanogaster
    • Dscam1
    • Protein
    • Binding
    • Self-avoidance
    • System
    • Also
    • Proteins
    • Homophilic
    • Drosophila
    • Expression
    • Role
  • isoforms
    • Melanogaster
    • Dscam1
    • Protein
    • Binding
    • Also
    • Proteins
    • Homophilic
    • Self-avoidance
    • Drosophila
    • Expression
    • Role
  • down syndrome
    • Proteins
    • Chromosome
    • System
    • Genes
    • Neural
    • Band
    • Defects
    • Human
    • Molecules

Connections between topic areas Semantic bridges

For DSCAM, one of the stronger structural bridges in this analysis connects DSCAM with Gene. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
DSCAMGene · splits 57 ⟂ 21
DSCAMClinical significance · splits 58 ⟂ 20
DSCAMFunctions · splits 61 ⟂ 17
DSCAMOverview · splits 68 ⟂ 10
DSCAMHistory/discovery · splits 71 ⟂ 7

Map overview Semantic statistics

DSCAM

Nodes78
Edges77
Triples156
Avg. degree1.97
Density0.025641
Components1

Source & methodology

TTTA analyzes the structure around DSCAM to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as History & Standards, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — DSCAM · EN edition · Analysis: TopicsToTalkAbout

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