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Spliceosome

A spliceosome is a large ribonucleoprotein (RNP) complex found primarily within the nucleus of eukaryotic cells. The spliceosome is assembled from small nuclear RNAs (snRNA) and numerous proteins. Small nuclear RNA (snRNA) molecules bind to specific proteins to form a small nuclear ribonucleoprotein complex (snRNP, pronounced "snurps"), which in turn…

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Composition

Small nuclear RNAsSnRNPsU1U2U4
12 related topics

History

Phillip SharpRichard J. RobertsNon-coding DNA5'3'
6 related topics

Alternative splicing

ExonsGenetic diversitySplice variantsGenesHuman genome
8 related topics

Minor spliceosome

Minor spliceosomeU11U12U4atacU6atac
6 related topics

Topics to explore

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Overview

History

Composition

Alternative splicing

Location of splicing

Assembly

Minor spliceosome

Advanced semantic analysis

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Map overview Semantic statistics

Spliceosome

Nodes53
Edges52
Triples50
Avg. degree1.96
Density0.037736
Components1

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Spliceosome

Top relations

related to Assembly · 15
Spliceosome → ATP-dependent, ATP-independent, BPS, Figure, In, It, OH, RNA-RNA, Specifically, The, The U4/U5/U6, U1, U2, U2AF, U6
related to Composition · 13
Spliceosome → Each, RNA, RNA-protein, RNA-RNA, RNAs, The, These, U1, U2, U4, U5, U6, When
related to Minor spliceosome · 8
Spliceosome → Some, The, U11, U12, U12-type, U4atac, U5, U6atac
related to External links · 6
Spliceosome → EM Data Bank, EMDB, Medicine Medical Subject Headings, MeSH, National Library, Spliceosomes
related to Location of splicing · 6
Spliceosome → By, Genes, In, It, Pre-mRNA, RNA
is a · 1
Spliceosome → large ribonucleoprotein
located in · 1
Spliceosome → the nucleus like its major counterpart

Important terminology Word statistics

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Important terminology

splicing u2 snrnp complex pre-mrna snrna nuclear introns site 5' u6 splice branch citation needed small 3' u5 factors sequence

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Spliceosomeis alarge ribonucleoprotein0.90text
Spliceosomelocated inthe nucleus like its major counterpart0.90text
Spliceosomerelated to AssemblyThe0.60section
Spliceosomerelated to AssemblyU10.60section
Spliceosomerelated to AssemblyATP-independent0.60section
Spliceosomerelated to AssemblyU20.60section
Spliceosomerelated to AssemblyU2AF0.60section
Spliceosomerelated to AssemblyIn0.60section
Spliceosomerelated to AssemblyATP-dependent0.60section
Spliceosomerelated to AssemblyBPS0.60section
Spliceosomerelated to AssemblyRNA-RNA0.60section
Spliceosomerelated to AssemblySpecifically0.60section

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    Min side: 3
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