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Ceramide

Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid joined by an amide bond. Ceramides are found in high concentrations within the cell membrane of eukaryotic cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. Contrary to previous assumptions…

Applications, Pathways for ceramide synthesis & Physiological roles

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Pathways for ceramide synthesis

De novoReacylationHydrolysisSphingomyelinasePhospholipids
21 related topics

Physiological roles

SenescenceCancerNeurodegenerationDiabetesObesity
38 related topics

Substances known to induce ceramide generation

AnandamideFas ligandEndotoxinHomocysteineGamma interferon
11 related topics

Overview

WaxLipidSphingosineFatty acidAmide bond
17 related topics

Topics to explore

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Overview

Pathways for ceramide synthesis

Physiological roles

Substances known to induce ceramide generation

Mechanism by which ceramide signaling occurs

Related diseases

Uses

Ceramide in bacteria

Ceramide phosphoethanolamine

Advanced semantic analysis

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Map overview Semantic statistics

Ceramide

Nodes106
Edges105
Triples84
Avg. degree1.98
Density0.018868
Components1

How this topic connects Entity context

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Ceramide

Top relations

related to Skin · 14
Ceramide → ADS, AH, AP, As, EOH, EOS, Epidermal, It, NDS, NH, NP, NS, The, Together
related to Pathology · 12
Ceramide → Although, As, C16, C16-C18, C18, C24, Dietary, Interventions, MACE, NAFLD, Roles, Several
related to Apoptosis · 9
Ceramide → Apoptosis, Because, However, One, Several, This, TNF-alpha, Type, UV
related to De novo · 7
Ceramide → CERT, De, Golgi, In, Once, The, This
related to External links · 4
Ceramide → Ceramides, Medicine Medical Subject Headings, MeSH, National Library
related to Hormonal · 4
Ceramide → An, Inhibition, JNK, SOCS-3
related to Pathways for ceramide synthesis · 4
Ceramide → First, Second, There, Third
related to Related diseases · 4
Ceramide → ACSF3, CMAMMA, For, In
related to Salvage pathway · 4
Ceramide → Constitutive, In, The, Thus
related to Ceramide phosphoethanolamine · 3
Ceramide → CPE, Drosophila, In

Important terminology Word statistics

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Important terminology

ceramides lipid cell sphingomyelin sphingosine found cells fatty membrane pathway skin apoptosis synthesis also insulin resistance signaling sphingolipids form one

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
CeramidecausesLDL retention in arterial walls0.90text
Ceramideis acomponent of vernix caseosa0.90text
eczemainstance ofUsesCeramides may be found as ingredients of some topical skin medications used to complement treatment for skin conditions0.80text
some soapsinstance ofThey are also used in cosmetic products0.80text
shampoosinstance ofThey are also used in cosmetic products0.80text
skin creamsinstance ofThey are also used in cosmetic products0.80text
and sunscreensinstance ofThey are also used in cosmetic products0.80text
members of Drosophilainstance ofCPE is the major sphingolipid class in some invertebrates0.80text
Ceramiderelated to ApoptosisOne0.60section
Ceramiderelated to ApoptosisApoptosis0.60section
Ceramiderelated to ApoptosisType0.60section
Ceramiderelated to ApoptosisUV0.60section

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