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Cyclin B

Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). The complex of Cdk and cyclin B is called maturation…

Role in Cancer, Function & Overview

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Alt. symbols
CCNB
Domains
InterPro
HGNC
1579
Locus
Chr. 5 q12
NCBI gene
891
OMIM
123836

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Overview

Function

Role in Cancer

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Map overview Semantic statistics

Cyclin B

Nodes20
Edges19
Triples57
Avg. degree1.9
Density0.1
Components1

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Cyclin B

Top relations

related to Function · 11
Cyclin B → At, B/CDK1, CDK1, Cross-talk, Cyclin, DNA, However, In, Survivin, The, Upon
related to As a Biomarker · 9
Cyclin B → Cyclin, Generally, However, Immunohistologically, In, Many, The, Therefore, These
related to Role in Cancer · 9
Cyclin B → B/CDK1, Because, CDK1, Cyclin, Hyperplasia, Most, On, Some, When
related to Cyclin B and p53 · 7
Cyclin B → CDK1, In, It, There, Therefore, WAF1, When
related to External links · 6
Cyclin B → Cyclin, Drosophila Cyclin, Medicine Medical Subject Headings, MeSH, National Library, The Interactive Fly
is a · 3
Cyclin B → member of the cyclin family, mitotic cyclin, strong indicator of prognosis in many types of cancer
Alt. symbols · 1
Cyclin B → CCNB
Domains · 1
Cyclin B → InterPro
HGNC · 1
Cyclin B → 1579
Locus · 1
Cyclin B → Chr. 5 q12

Important terminology Word statistics

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Important terminology

cyclin levels cancer cell complex cdk1 mitosis p53 cells therefore also cancers mitotic necessary phase elevated prognosis aggressive cycle survivin

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Cyclin BAlt. symbolsCCNB1.00infobox
Cyclin BDomainsInterPro1.00infobox
Cyclin BHGNC15791.00infobox
Cyclin BLocusChr. 5 q121.00infobox
Cyclin BNCBI gene8911.00infobox
Cyclin BOMIM1238361.00infobox
Cyclin BRefSeqNM_0319661.00infobox
Cyclin BSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Cyclin BStructuresSwiss-model1.00infobox
Cyclin BSymbolCCNB11.00infobox
Cyclin BUniProtP146351.00infobox
Cyclin Bis amember of the cyclin family0.90text
Cyclin Bis amitotic cyclin0.90text
Cyclin Bis astrong indicator of prognosis in many types of cancer0.90text

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    Min side: 3
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