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Cyclin B: Role in Cancer, Function & Overview

Cyclin B is a member of the cyclin family. Cyclin B is a mitotic cyclin. The amount of cyclin B (which binds to Cdk1) and the activity of the cyclin B-Cdk complex rise through the cell cycle until mitosis, where they fall abruptly due to degradation of cyclin B (Cdk1 is constitutively present). The complex of Cdk and cyclin B is called maturation…

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Cyclin B topic overview

The analysis highlights Role in Cancer, Function and Overview as prominent areas in the source structure around Cyclin B.

Related topics
16
Source areas
3
Connected nodes
19
Extracted relationships
57
Concept neighborhoods
15
Bridge connections
19

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Role in Cancer · 9 topics
Overview · 5 topics
Function · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Alt. symbols
CCNB
Domains
InterPro
HGNC
1579
Locus
Chr. 5 q12
NCBI gene
891
OMIM
123836

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Role in Cancer

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Cyclin B connects Entity context

The extracted context around Cyclin B shows recurring relationship patterns in the source. For example, Cyclin B → At, B/CDK1, CDK1, Cross-talk, Cyclin, DNA, However, In, Survivin, The, Upon Another extracted example is Cyclin B → Cyclin, Generally, However, Immunohistologically, In, Many, The, Therefore, These. Use these groups to spot repeated connection types before inspecting the individual relationships.

Cyclin B

Top relations

related to Function · 11
Cyclin B → At, B/CDK1, CDK1, Cross-talk, Cyclin, DNA, However, In, Survivin, The, Upon
related to As a Biomarker · 9
Cyclin B → Cyclin, Generally, However, Immunohistologically, In, Many, The, Therefore, These
related to Role in Cancer · 9
Cyclin B → B/CDK1, Because, CDK1, Cyclin, Hyperplasia, Most, On, Some, When
related to Cyclin B and p53 · 7
Cyclin B → CDK1, In, It, There, Therefore, WAF1, When
related to External links · 6
Cyclin B → Cyclin, Drosophila Cyclin, Medicine Medical Subject Headings, MeSH, National Library, The Interactive Fly
is a · 3
Cyclin B → member of the cyclin family, mitotic cyclin, strong indicator of prognosis in many types of cancer
Alt. symbols · 1
Cyclin B → CCNB
Domains · 1
Cyclin B → InterPro
HGNC · 1
Cyclin B → 1579
Locus · 1
Cyclin B → Chr. 5 q12

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

cyclin levels cancer cell complex cdk1 mitosis p53 cells therefore also cancers mitotic necessary phase elevated prognosis aggressive cycle survivin

Cyclin B relationships Subject–Predicate–Object triples

TTTA extracted 57 structured relationships around Cyclin B. Examples in this analysis include Cyclin B → Alt. symbols → CCNB and Cyclin B → Domains → InterPro. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Cyclin BAlt. symbolsCCNB1.00infobox
Cyclin BDomainsInterPro1.00infobox
Cyclin BHGNC15791.00infobox
Cyclin BLocusChr. 5 q121.00infobox
Cyclin BNCBI gene8911.00infobox
Cyclin BOMIM1238361.00infobox
Cyclin BRefSeqNM_0319661.00infobox
Cyclin BSearch forSearch forStructuresSwiss-modelDomainsInterPro1.00infobox
Cyclin BStructuresSwiss-model1.00infobox
Cyclin BSymbolCCNB11.00infobox
Cyclin BUniProtP146351.00infobox
Cyclin Bis amember of the cyclin family0.90text
Cyclin Bis amitotic cyclin0.90text
Cyclin Bis astrong indicator of prognosis in many types of cancer0.90text

Related concept clusters Concept neighborhoods

The concept neighborhoods around Cyclin B bring nearby vocabulary together. In this analysis, examples include Levels, Cell and Cancer. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Cyclin B
    • Levels
    • Cell
    • Cancer
    • Cells
    • Cdk1
    • Complex
    • P53
    • Also
    • Cancers
    • Mitosis
    • Elevated
    • Necessary
  • cyclin b
    • Levels
    • Cell
    • Cancer
    • Cells
    • Cdk1
    • Complex
    • P53
    • Also
    • Cancers
    • Mitosis
    • Elevated
    • Necessary
  • cyclin
    • Levels
    • Cell
    • Cancer
    • Cells
    • Cdk1
    • Complex
    • P53
    • Also
    • Cancers
    • Mitosis
    • Elevated
    • Necessary
  • cdk1
    • Complex
    • Cell
    • Proteins
    • Cdc25c
    • Cyclinb
    • Cycle
    • Cyclin
    • Division
    • Progression
    • Phase
    • Mitosis
    • Therefore
  • cell cycle
    • Progression
    • Necessary
    • Cells
    • Complex
    • Mitosis
    • Cycle
    • Division
    • Cyclin
    • Activation
    • Cyclinb
    • Degradation
    • Phase
  • cell cycle arrest
    • Progression
    • Necessary
    • Cells
    • Complex
    • Mitosis
    • Cycle
    • Division
    • Cyclin
    • Activation
    • Cyclinb
    • Degradation
    • Phase
  • role in cancer
    • Cells
    • Cyclin
    • Cell
    • Survivin
    • Levels
    • Biomarker
    • Division
    • Function
    • Many
    • Role
    • Aggressive
    • Elevated
  • p53
    • Gene
    • Tumor
    • Levels
    • Therefore
    • Cells
    • Activation
    • Cross-talk
    • Cyclinb
    • Links
    • Pathways
    • Progression
    • Proteins

Connections between topic areas Semantic bridges

For Cyclin B, one of the stronger structural bridges in this analysis connects Cyclin B with Role in Cancer. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Cyclin B — Role in Cancer · splits 10 ⟂ 10
Cyclin B — Overview · splits 14 ⟂ 6
Cyclin B — Function · splits 17 ⟂ 3

Map overview Semantic statistics

Cyclin B

Nodes20
Edges19
Triples57
Avg. degree1.9
Density0.1
Components1

Source & methodology

TTTA analyzes the structure around Cyclin B to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Role in Cancer, Function & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Cyclin B · EN edition · Analysis: TopicsToTalkAbout

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