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Securin

Securin is a protein involved in control of the metaphase-anaphase transition and anaphase onset. Following bi-orientation of chromosome pairs and inactivation of the spindle checkpoint system, the underlying regulatory system, which includes securin, produces an abrupt stimulus that induces highly synchronous chromosome separation in anaphase.

Securin and Separase, Role of Securin in the onset of Anaphase & Overview

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Securin and Separase

SeparaseProteaseCdk1
3 related topics

Role of Securin in the onset of Anaphase

Cdc14Cdc20Positive feedback
3 related topics

Overview

ProteinChromosomeAnaphase
3 related topics

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Overview

Securin and Separase

Role of Securin in the onset of Anaphase

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Map overview Semantic statistics

Securin

Nodes13
Edges12
Triples38
Avg. degree1.85
Density0.153846
Components1

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Securin

Top relations

related to Basic mechanism · 14
Securin → Anaphase-Promoting Complex, APC, Cdc14, Cdc20, Cdh1, Cdk1, D-box, Dephosphorylated, Figure, Ken-Box, N-terminal, The APCCdc20, This, To
related to Network characteristics · 9
Securin → Cdc14, David Morgan’s, Figure, In, It, N-terminal, One, Switch, This
related to Securin and Separase · 8
Securin → Cdk1, Figure, However, In, Note, Separase, This, When
related to External links · 6
Securin → Anaphase Onset, Cell Cycle, Controlling, David Morgan, MP4, Video
is a · 1
Securin → protein involved in control of the metaphase-anaphase transition and anaphase onset

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Important terminology

separase anaphase onset network complex figure chromosome functional activation behavior inactivation regulatory separation characteristics cdk1 cdc14 protein initially cohesin two

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Securinis aprotein involved in control of the metaphase-anaphase transition and anaphase onset0.90text
Securinrelated to Basic mechanismCdk10.60section
Securinrelated to Basic mechanismN-terminal0.60section
Securinrelated to Basic mechanismKen-Box0.60section
Securinrelated to Basic mechanismD-box0.60section
Securinrelated to Basic mechanismAPC0.60section
Securinrelated to Basic mechanismFigure0.60section
Securinrelated to Basic mechanismTo0.60section
Securinrelated to Basic mechanismCdc140.60section
Securinrelated to Basic mechanismDephosphorylated0.60section
Securinrelated to Basic mechanismAnaphase-Promoting Complex0.60section
Securinrelated to Basic mechanismCdc200.60section

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