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Valdecoxib

Valdecoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a selective cyclooxygenase-2 inhibitor. It was patented in 1995.

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Explore the main themes, entities and connections around Valdecoxib. Start with the topic map, then use the sections below for research and deeper semantic analysis.

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Side effects and withdrawal from market

9 related topics

2009 settlement for off-label uses promotions

5 related topics

Overview

13 related topics

Uses until 2005

2 related topics

Key facts & relationships

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3D model (JSmol)
Interactive image
ATC code
M01AH03 (WHO)
Bioavailability
83%
CAS Number
181695-72-7 N
ChEBI
CHEBI:63634 N
ChEMBL
ChEMBL865 Y

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Overview

Uses until 2005

Side effects and withdrawal from market

2009 settlement for off-label uses promotions

Advanced semantic analysis

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Map overview Semantic statistics

Valdecoxib

Nodes34
Edges33
Triples33
Avg. degree1.94
Density0.058824
Components1

How this topic connects Entity context

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Valdecoxib

Top relations

Legal status · 3
Valdecoxib → AU: S4 (Prescription only), BR: Class C1 (Other controlled substances), Withdrawn in U.S., EU, Canada and parts of Asia
related to Uses until 2005 · 3
Valdecoxib → FDA, In, United States
Pregnancy category · 2
Valdecoxib → AU: C, May cause premature closure of the ductus arteriosus
has method · 2
Valdecoxib → HPTLC, Several HPLC-UV
3D model (JSmol) · 1
Valdecoxib → Interactive image
ATC code · 1
Valdecoxib → M01AH03 (WHO)
Bioavailability · 1
Valdecoxib → 83%
CAS Number · 1
Valdecoxib → 181695-72-7 N
ChEBI · 1
Valdecoxib → CHEBI:63634 N
ChEMBL · 1
Valdecoxib → ChEMBL865 Y

Important terminology Word statistics

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Important terminology

bextra pfizer drug fda arthritis company united states settlement largest billion 2005 market 2009 prescription american risk adverse fine anti-inflammatory

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Valdecoxib3D model (JSmol)Interactive image1.00infobox
ValdecoxibATC codeM01AH03 (WHO)1.00infobox
ValdecoxibBioavailability83%1.00infobox
ValdecoxibCAS Number181695-72-7 N1.00infobox
ValdecoxibChEBICHEBI:63634 N1.00infobox
ValdecoxibChEMBLChEMBL865 Y1.00infobox
ValdecoxibChemSpider106796 Y1.00infobox
ValdecoxibCompTox Dashboard (EPA)DTXSID60442261.00infobox
ValdecoxibDrugBankDB00580 Y1.00infobox
ValdecoxibECHA InfoCard100.229.9181.00infobox
ValdecoxibElimination half-life8 to 11 hours1.00infobox
ValdecoxibExcretionRenal1.00infobox
ValdecoxibFormulaC16H14N2O3S1.00infobox
ValdecoxibIUPHAR/BPS28941.00infobox
ValdecoxibKEGGD02709 Y1.00infobox
ValdecoxibLegal statusAU: S4 (Prescription only)1.00infobox
ValdecoxibLegal statusBR: Class C1 (Other controlled substances)1.00infobox
ValdecoxibLegal statusWithdrawn in U.S., EU, Canada and parts of Asia1.00infobox
ValdecoxibMetabolismHepatic (CYP3A4 and 2C9 involved)1.00infobox
ValdecoxibMolar mass314.36 g·mol−11.00infobox
ValdecoxibPregnancy categoryAU: C1.00infobox
ValdecoxibPregnancy categoryMay cause premature closure of the ductus arteriosus1.00infobox
ValdecoxibProtein binding98%1.00infobox
ValdecoxibPubChem CID1196071.00infobox
ValdecoxibRoutes of administrationOral1.00infobox
ValdecoxibTrade namesBextra1.00infobox
ValdecoxibUNII2919279Q3W1.00infobox
Valdecoxibis anonsteroidal anti-inflammatory drug0.90text

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