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Muscarinic acetylcholine receptor M1: Ligands, Effects & Occurrence in human pathogenic amoebae

The muscarinic acetylcholine receptor M1, also known as the cholinergic receptor, muscarinic 1, is a muscarinic receptor that in humans is encoded by the CHRM1 gene. It is localized to 11q13.

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Muscarinic acetylcholine receptor M1 topic overview

The analysis highlights Ligands, Effects and Occurrence in human pathogenic amoebae as prominent areas in the source structure around Muscarinic acetylcholine receptor M1.

Related topics
81
Source areas
5
Connected nodes
86
Extracted relationships
105
Concept neighborhoods
17
Bridge connections
86

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Ligands · 42 topics
Effects · 19 topics
Overview · 10 topics
Occurrence in human pathogenic amoebae · 6 topics
Mechanism · 4 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV
Band
11q12.3 · 19|19 A
Bgee
prefrontal cortex · middle temporal gyrus · Brodmann area 9 · right frontal lobe · superior frontal gyrus
BioGPS
n/a
Chr.
Chromosome 11 (human) · Chromosome 19 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Effects

Occurrence in human pathogenic amoebae

Mechanism

Ligands

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Muscarinic acetylcholine receptor M1 connects Entity context

The extracted context around Muscarinic acetylcholine receptor M1 shows recurring relationship patterns in the source. For example, Muscarinic acetylcholine receptor M1 → adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway, asymmetric synapse, axon terminus, cell junction, cell population proliferation, chemical synaptic transmission, cholinergic synapse, cognition, dendrite, G protein-coupled acetylcholine receptor activity, G protein-coupled acetylcholine receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin receptor activity, G protein-coupled serotonin receptor signaling pathway, glutamatergic synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic density membrane Another extracted example is Muscarinic acetylcholine receptor M1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory tubercle, perirhinal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, superior frontal gyrus. Use these groups to spot repeated connection types before inspecting the individual relationships.

Muscarinic acetylcholine receptor M1

Top relations

Gene ontology · 46
Muscarinic acetylcholine receptor M1 → adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway, asymmetric synapse, axon terminus, cell junction, cell population proliferation, chemical synaptic transmission, cholinergic synapse, cognition, dendrite, G protein-coupled acetylcholine receptor activity, G protein-coupled acetylcholine receptor signaling pathway, G protein-coupled receptor activity, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin receptor activity, G protein-coupled serotonin receptor signaling pathway, glutamatergic synapse, integral component of membrane, integral component of plasma membrane, integral component of postsynaptic density membrane
Bgee · 17
Muscarinic acetylcholine receptor M1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory tubercle, perirhinal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, superior frontal gyrus
RNA expression pattern · 17
Muscarinic acetylcholine receptor M1 → anterior cingulate cortex, Brodmann area 9, cingulate gyrus, dentate gyrus of hippocampal formation granule cell, hippocampus proper, middle temporal gyrus, nucleus accumbens, olfactory tubercle, perirhinal cortex, piriform cortex, postcentral gyrus, prefrontal cortex, primary motor cortex, primary visual cortex, putamen, right frontal lobe, superior frontal gyrus
Band · 2
Muscarinic acetylcholine receptor M1 → 11q12.3, 19|19 A
Chr. · 2
Muscarinic acetylcholine receptor M1 → Chromosome 11 (human), Chromosome 19 (mouse)
End · 2
Muscarinic acetylcholine receptor M1 → 62,921,807 bp, 8,660,951 bp
Aliases · 1
Muscarinic acetylcholine receptor M1 → CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1
Available structures · 1
Muscarinic acetylcholine receptor M1 → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV
BioGPS · 1
Muscarinic acetylcholine receptor M1 → n/a
Databases · 1
Muscarinic acetylcholine receptor M1 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

receptor human bp m1 chr band gene chromosome 11 also chrm1 muscarinic acetylcholine cholinergic epsp gq ctx ptx location mediating

Muscarinic acetylcholine receptor M1 relationships Subject–Predicate–Object triples

TTTA extracted 105 structured relationships around Muscarinic acetylcholine receptor M1. Examples in this analysis include Muscarinic acetylcholine receptor M1 → Aliases → CHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 1 and Muscarinic acetylcholine receptor M1 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Muscarinic acetylcholine receptor M1AliasesCHRM1, HM1, M1, M1R, cholinergic receptor muscarinic 11.00infobox
Muscarinic acetylcholine receptor M1Available structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes5CXV1.00infobox
Muscarinic acetylcholine receptor M1Band11q12.31.00infobox
Muscarinic acetylcholine receptor M1Band19|19 A1.00infobox
Muscarinic acetylcholine receptor M1Bgeeprefrontal cortex1.00infobox
Muscarinic acetylcholine receptor M1Bgeemiddle temporal gyrus1.00infobox
Muscarinic acetylcholine receptor M1BgeeBrodmann area 91.00infobox
Muscarinic acetylcholine receptor M1Bgeeright frontal lobe1.00infobox
Muscarinic acetylcholine receptor M1Bgeesuperior frontal gyrus1.00infobox
Muscarinic acetylcholine receptor M1Bgeenucleus accumbens1.00infobox
Muscarinic acetylcholine receptor M1Bgeepostcentral gyrus1.00infobox
Muscarinic acetylcholine receptor M1Bgeecingulate gyrus1.00infobox
Muscarinic acetylcholine receptor M1Bgeeanterior cingulate cortex1.00infobox
Muscarinic acetylcholine receptor M1Bgeeputamen1.00infobox
Muscarinic acetylcholine receptor M1Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
Muscarinic acetylcholine receptor M1Bgeeprimary visual cortex1.00infobox
Muscarinic acetylcholine receptor M1Bgeehippocampus proper1.00infobox
Muscarinic acetylcholine receptor M1Bgeeolfactory tubercle1.00infobox
Muscarinic acetylcholine receptor M1Bgeeprimary motor cortex1.00infobox
Muscarinic acetylcholine receptor M1Bgeepiriform cortex1.00infobox
Muscarinic acetylcholine receptor M1Bgeeperirhinal cortex1.00infobox
Muscarinic acetylcholine receptor M1BioGPSn/a1.00infobox
Muscarinic acetylcholine receptor M1Chr.Chromosome 11 (human)1.00infobox
Muscarinic acetylcholine receptor M1Chr.Chromosome 19 (mouse)1.00infobox
Muscarinic acetylcholine receptor M1DatabasesNCBI: entry; OMA: entry1.00infobox
Muscarinic acetylcholine receptor M1End62,921,807 bp1.00infobox
Muscarinic acetylcholine receptor M1End8,660,951 bp1.00infobox
Muscarinic acetylcholine receptor M1EnsemblENSG000001685391.00infobox
Muscarinic acetylcholine receptor M1Entrez11281.00infobox
Muscarinic acetylcholine receptor M1External IDsOMIM: 118510; MGI: 88396; GeneCards: CHRM11.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Muscarinic acetylcholine receptor M1 bring nearby vocabulary together. In this analysis, examples include M1, Known and Receptor. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Muscarinic acetylcholine receptor M1
    • M1
    • Known
    • Receptor
    • Also
    • Cholinergic
    • Chrm1
    • Muscarinic
    • Gene
    • Certain
    • External
    • Glands
    • Intracellular
  • muscarinic acetylcholine receptor m1
    • M1
    • Muscarinic
    • Receptor
    • Cholinergic
    • Chrm1
    • Known
    • Also
    • Gene
    • Human
    • Certain
    • External
    • Glands
  • muscarinic receptor
    • M1
    • Known
    • Receptor
    • Also
    • Cholinergic
    • Chrm1
    • Gene
    • Human
    • External
    • Glands
    • Search
    • Cognitive
  • acetylcholine
    • Cholinergic
    • Chrm1
    • Gene
    • Muscarinic
    • Receptor
    • M1
    • Certain
    • Glands
    • Intracellular
    • Involved
    • Known
    • Mouse
  • gene
    • Location
    • Chromosome
    • Bp
    • Chr
    • Human
    • Mouse
    • Search
    • Band
    • Muscarinic
    • Receptor
    • External
    • M1
  • epsp
    • Glands
    • Slow
    • Mediating
    • Certain
    • Found
    • Intracellular
    • Involved
    • Mouse
    • Pathway
    • Phospholipase
    • Search
    • Cognitive
  • exocrine glands
    • Mediating
    • Certain
    • Intracellular
    • Involved
    • Mouse
    • Pathway
    • Phospholipase
    • Search
    • Slow
    • Cognitive
    • Location
    • Receptor
  • salivary glands
    • Mediating
    • Certain
    • Intracellular
    • Involved
    • Mouse
    • Pathway
    • Phospholipase
    • Search
    • Slow
    • Cognitive
    • Location
    • Receptor

Connections between topic areas Semantic bridges

For Muscarinic acetylcholine receptor M1, one of the stronger structural bridges in this analysis connects Muscarinic acetylcholine receptor M1 with Ligands. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Muscarinic acetylcholine receptor M1Ligands · splits 44 ⟂ 43
Muscarinic acetylcholine receptor M1Effects · splits 67 ⟂ 20
Muscarinic acetylcholine receptor M1Overview · splits 76 ⟂ 11
Muscarinic acetylcholine receptor M1Occurrence in human pathogenic amoebae · splits 80 ⟂ 7
Muscarinic acetylcholine receptor M1Mechanism · splits 82 ⟂ 5

Map overview Semantic statistics

Muscarinic acetylcholine receptor M1

Nodes87
Edges86
Triples105
Avg. degree1.98
Density0.022989
Components1

Source & methodology

TTTA analyzes the structure around Muscarinic acetylcholine receptor M1 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Ligands, Effects & Occurrence in human pathogenic amoebae, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Muscarinic acetylcholine receptor M1 · EN edition · Analysis: TopicsToTalkAbout

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