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Substrate presentation

In molecular biology, substrate presentation is a biological process that activates a protein. The protein is sequestered away from its substrate and then activated by release and exposure to its substrate. A substrate is typically the substance on which an enzyme acts but can also be a protein surface to which a ligand binds. In the case of an…

Examples, Role in biology & Mechanisms of activation

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Examples

Mechanisms of activation

Regulation

Role in biology

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Map overview Semantic statistics

Substrate presentation

Nodes61
Edges60
Triples47
Avg. degree1.97
Density0.032787
Components1

How this topic connects Entity context

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Substrate presentation

Top relations

related to Amyloid precursor protein · 12
Substrate presentation → Alzheimer's, Amyloid, ApoE, APP, Cholesterol, For, GM1, Hydrophobicity, In, Raft, The, When
related to PUFAs · 10
Substrate presentation → Arachidonyl PC, PA, PC, PIP2, PLD, PUFA, PUFAs, Regulation, The, While
related to Kinase Signaling · 9
Substrate presentation → Activation, Its, Once, PKC, Protein Kinase, Receptor Tyrosine Kinases, RTKs, This, Thus
related to Anaesthesia · 8
Substrate presentation → Activation, General, Membrane-mediated, PLD, PLD2, The, TRAAK, TREK-1
related to Phospholipase D2 · 7
Substrate presentation → GM1, PC, PIP2, PLD2, Presumably, The, When PIP2
is a · 1
Substrate presentation → biological process that activates a protein

Important terminology Word statistics

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Important terminology

substrate lipid cholesterol protein enzyme rafts citation needed presentation raft pld2 pip2 membrane palmitoylated gm1 activation sequestration regulation cell also

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Substrate presentationis abiological process that activates a protein0.90text
Substrate presentationrelated to Amyloid precursor proteinAmyloid0.60section
Substrate presentationrelated to Amyloid precursor proteinAPP0.60section
Substrate presentationrelated to Amyloid precursor proteinAlzheimer's0.60section
Substrate presentationrelated to Amyloid precursor proteinThe0.60section
Substrate presentationrelated to Amyloid precursor proteinGM10.60section
Substrate presentationrelated to Amyloid precursor proteinCholesterol0.60section
Substrate presentationrelated to Amyloid precursor proteinApoE0.60section
Substrate presentationrelated to Amyloid precursor proteinWhen0.60section
Substrate presentationrelated to Amyloid precursor proteinHydrophobicity0.60section
Substrate presentationrelated to Amyloid precursor proteinIn0.60section
Substrate presentationrelated to Amyloid precursor proteinFor0.60section

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