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Fentanyl

Fentanyl is a highly potent synthetic opioid of the piperidine family, used primarily as pain medication. It is 50 to 100 times more potent than morphine. Its primary clinical use is in pain management for cancer patients and those recovering from surgery. Fentanyl is also used as a sedative for intubated patients. Fentanyl has a short duration of…

History, Community, Culture & Applications

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Explore this topic

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Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

3D model (JSmol)
Interactive image
AHFS/Drugs.com
Monograph
ATC code
N01AH01 (WHO) N02AB03 (WHO)
Bioavailability
Transdermal: 90–92% · Intranasal: 89% · Buccal: 51% (tablets), 71% (film) · Sublingual: 54% (Abstral tablets), 76% (spray) · Oral: 35%
CAS Number
437-38-7
ChEBI
CHEBI:119915

Topics to explore

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Overview

Medical uses

Adverse effects

Overdose

Pharmacology

Synthesis

History

Society and culture

Veterinary use

Advanced semantic analysis

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Map overview Semantic statistics

Fentanyl

Nodes219
Edges218
Triples315
Avg. degree1.99
Density0.009132
Components1

How this topic connects Entity context

See the strongest relationship patterns around the current topic before diving into the raw triples.

Fentanyl

Top relations

related to Enforcement · 29
Fentanyl → AMF, Arizona, Border Protection, China, China White, Cottonwood Heights, Customs, DEA, February, In November, Justice, Many, Mexican, Mexico, Nogales, One US Department, Part, Schedule, Several, Some
has effect · 19
Fentanyl → After, April, Despite, Drug Administration, Existing, FDA, Fentanyl's, In, Less, Pain, Primarily, Sedation, September, SSRI, Suppression, The, The FDA, United Kingdom, United States Food
related to External links · 15
Fentanyl → Archived, DEA, December, Drug Abuse, Drug Enforcement Administration, EUDA, European Union Drugs Agency, Health, July, June, National Institute, NIDA, NIOSH, Occupational Safety, Report
has prevention · 12
Fentanyl → An, CDC, December, Disease Control, HAN Advisory, HAN Alert, Health Alert Network Advisory, July, October, Prevention, Public, US Centers
related to Overdose · 12
Fentanyl → Healthcare, In, In July, Medicines, MHRA, Naloxone, Narcan, Over, Regulatory Agency, The, UK, US
related to history · 11
Fentanyl → After, Belgium, Demerol, Duragesic, In, It, Janssen Pharmaceutica, McNeil Laboratories, Paul Janssen, Sublimaze, The
Legal status · 10
Fentanyl → AU: S8 (Controlled drug), BR: Class A1 (Narcotic drugs), CA: Schedule I, DE: Anlage III (Special prescription form required), EU: Rx-only, NZ: Class B, SE: Förteckning II, UK: Class A, UN: Narcotic Schedule I, US: Schedule II
related to Detection for harm reduction purposes · 10
Fentanyl → BTNX, Dr, Following, Lieberman's, MDMA, Notre Dame, Research, The, To, University
related to Economics · 10
Fentanyl → As, AU, Australian Institute, Criminology, DreamMarket, Fu-F, Furthermore, In, United States, US
related to Mechanism of action · 10
Fentanyl → A-fibers, C-fibers, C-terminus, G-protein-coupled, It, N-terminus, The, These, This, When

Important terminology Word statistics

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

drug used deaths united opioid drugs overdose states use pain effects us also may respiratory administration synthetic high heroin anesthesia

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
Fentanyl3D model (JSmol)Interactive image1.00infobox
FentanylAHFS/Drugs.comMonograph1.00infobox
FentanylATC codeN01AH01 (WHO) N02AB03 (WHO)1.00infobox
FentanylBioavailabilityTransdermal: 90–92%1.00infobox
FentanylBioavailabilityIntranasal: 89%1.00infobox
FentanylBioavailabilityBuccal: 51% (tablets), 71% (film)1.00infobox
FentanylBioavailabilitySublingual: 54% (Abstral tablets), 76% (spray)1.00infobox
FentanylBioavailabilityOral: 35%1.00infobox
FentanylBioavailabilityInhalation: 56–96%1.00infobox
FentanylBioavailabilityIM & IV: 100%1.00infobox
FentanylCAS Number437-38-71.00infobox
FentanylChEBICHEBI:1199151.00infobox
FentanylChEMBLChEMBL5961.00infobox
FentanylChemSpider32281.00infobox
FentanylCompTox Dashboard (EPA)DTXSID90230491.00infobox
FentanylDensity1.1 g/cm31.00infobox
FentanylDependence liabilityHigh1.00infobox
FentanylDrug classOpioid1.00infobox
FentanylDrugBankDB008131.00infobox
FentanylDuration of actionIV: 30–60 minutes1.00infobox
FentanylECHA InfoCard100.006.4681.00infobox
FentanylElimination half-lifeIV: 6 mins (T1/2 α) 1 hours (T1/2 β) 16 hours (T1/2 ɣ)[citation needed] Intranasal: 15–25 hours Transdermal: 20–27 hours Sublingual: 5–13.5 hours Buccal: 3.2–6.4 hours1.00infobox
FentanylExcretionMostly urinary (metabolites, < 10% unchanged drug)1.00infobox
FentanylFormulaC22H28N2O1.00infobox
FentanylIUPHAR/BPS16261.00infobox
FentanylKEGGD003201.00infobox
FentanylLegal statusAU: S8 (Controlled drug)1.00infobox
FentanylLegal statusBR: Class A1 (Narcotic drugs)1.00infobox
FentanylLegal statusCA: Schedule I1.00infobox
FentanylLegal statusDE: Anlage III (Special prescription form required)1.00infobox

Related concept clusters Concept neighborhoods

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    Min side: 3
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