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Insulin-like growth factor 2: Regions, Clinical relevance & Gene structure

Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity with insulin. The MeSH definition reads: "A well-characterized neutral peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not…

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Insulin-like growth factor 2 topic overview

The analysis highlights Regions, Clinical relevance and Gene structure as prominent areas in the source structure around Insulin-like growth factor 2.

Related topics
36
Source areas
5
Connected nodes
41
Extracted relationships
91
Concept neighborhoods
18
Bridge connections
41

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Clinical relevance · 10 topics
Function · 9 topics
Gene structure · 9 topics
Overview · 5 topics
Interactions · 3 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2
Band
7 F5|7 87.99 cM
Bgee
extraembryonic membrane · yolk sac · genital tubercle · placenta · tail of embryo
BioGPS
n/a
Chr.
Chromosome 7 (human)
Databases
NCBI: entry; OMA: entry

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Gene structure

Function

Clinical relevance

Interactions

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Insulin-like growth factor 2 connects Entity context

The extracted context around Insulin-like growth factor 2 shows recurring relationship patterns in the source. For example, Insulin-like growth factor 2 → animal organ morphogenesis, carbohydrate metabolic process, collagen-containing extracellular matrix, embryonic placenta development, embryonic placenta morphogenesis, exocrine pancreas development, extracellular region, extracellular space, glucose metabolic process, growth factor activity, hormone activity, in utero embryonic development, insulin receptor binding, insulin receptor signaling pathway via phosphatidylinositol 3-kinase, insulin-like growth factor receptor binding, integrin binding, memory, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of transcription by RNA polymerase II, ossification Another extracted example is Insulin-like growth factor 2 → dentate gyrus of hippocampal formation granule cell, extraembryonic membrane, genital tubercle, intra-embryonic coelom, mesencephalon, neural tube, placenta, rhombencephalon, tail of embryo, yolk sac. Use these groups to spot repeated connection types before inspecting the individual relationships.

Insulin-like growth factor 2

Top relations

Gene ontology · 49
Insulin-like growth factor 2 → animal organ morphogenesis, carbohydrate metabolic process, collagen-containing extracellular matrix, embryonic placenta development, embryonic placenta morphogenesis, exocrine pancreas development, extracellular region, extracellular space, glucose metabolic process, growth factor activity, hormone activity, in utero embryonic development, insulin receptor binding, insulin receptor signaling pathway via phosphatidylinositol 3-kinase, insulin-like growth factor receptor binding, integrin binding, memory, negative regulation of natural killer cell mediated cytotoxicity, negative regulation of transcription by RNA polymerase II, ossification
Bgee · 10
Insulin-like growth factor 2 → dentate gyrus of hippocampal formation granule cell, extraembryonic membrane, genital tubercle, intra-embryonic coelom, mesencephalon, neural tube, placenta, rhombencephalon, tail of embryo, yolk sac
RNA expression pattern · 10
Insulin-like growth factor 2 → dentate gyrus of hippocampal formation granule cell, extraembryonic membrane, genital tubercle, intra-embryonic coelom, mesencephalon, neural tube, placenta, rhombencephalon, tail of embryo, yolk sac
related to Interactions · 2
Insulin-like growth factor 2 → IGFBP3, Insulin-like
see also · 2
Insulin-like growth factor 2 → II IRES, Insulin-like
Aliases · 1
Insulin-like growth factor 2 → insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2
Band · 1
Insulin-like growth factor 2 → 7 F5|7 87.99 cM
BioGPS · 1
Insulin-like growth factor 2 → n/a
Chr. · 1
Insulin-like growth factor 2 → Chromosome 7 (human)
Databases · 1
Insulin-like growth factor 2 → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

igf-2 growth insulin-like igf2 factor region gene hormone chromosome human insulin preptin expression bp peptide allele ctcf believed major receptor

Insulin-like growth factor 2 relationships Subject–Predicate–Object triples

TTTA extracted 91 structured relationships around Insulin-like growth factor 2. Examples in this analysis include Insulin-like growth factor 2 → Aliases → insulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg2 and Insulin-like growth factor 2 → Band → 7 F5|7 87.99 cM. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Insulin-like growth factor 2Aliasesinsulin-like growth factor 2AL033362Igf-2Igf-IIM6prMprPeg21.00infobox
Insulin-like growth factor 2Band7 F5|7 87.99 cM1.00infobox
Insulin-like growth factor 2Bgeeextraembryonic membrane1.00infobox
Insulin-like growth factor 2Bgeeyolk sac1.00infobox
Insulin-like growth factor 2Bgeegenital tubercle1.00infobox
Insulin-like growth factor 2Bgeeplacenta1.00infobox
Insulin-like growth factor 2Bgeetail of embryo1.00infobox
Insulin-like growth factor 2Bgeeneural tube1.00infobox
Insulin-like growth factor 2Bgeedentate gyrus of hippocampal formation granule cell1.00infobox
Insulin-like growth factor 2Bgeeintra-embryonic coelom1.00infobox
Insulin-like growth factor 2Bgeerhombencephalon1.00infobox
Insulin-like growth factor 2Bgeemesencephalon1.00infobox
Insulin-like growth factor 2BioGPSn/a1.00infobox
Insulin-like growth factor 2Chr.Chromosome 7 (human)1.00infobox
Insulin-like growth factor 2DatabasesNCBI: entry; OMA: entry1.00infobox
Insulin-like growth factor 2End142,220,553 bp1.00infobox
Insulin-like growth factor 2EnsemblENSMUSG000000485831.00infobox
Insulin-like growth factor 2Entrez160021.00infobox
Insulin-like growth factor 2External IDsGeneCards:1.00infobox
Insulin-like growth factor 2Gene location (Human)Gene location (Human)Chr.Chromosome 7 (human)Band7 F5|7 87.99 cMStart142,204,503 bpEnd142,220,553 bp1.00infobox
Insulin-like growth factor 2Gene ontologyhormone activity1.00infobox
Insulin-like growth factor 2Gene ontologyprotein serine/threonine kinase activator activity1.00infobox
Insulin-like growth factor 2Gene ontologyprotein binding1.00infobox
Insulin-like growth factor 2Gene ontologygrowth factor activity1.00infobox
Insulin-like growth factor 2Gene ontologyreceptor ligand activity1.00infobox
Insulin-like growth factor 2Gene ontologyinsulin receptor binding1.00infobox
Insulin-like growth factor 2Gene ontologyinsulin-like growth factor receptor binding1.00infobox
Insulin-like growth factor 2Gene ontologyintegrin binding1.00infobox
Insulin-like growth factor 2Gene ontologyextracellular region1.00infobox
Insulin-like growth factor 2Gene ontologyextracellular space1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Insulin-like growth factor 2 bring nearby vocabulary together. In this analysis, examples include Factor, Growth and Insulin-like. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Insulin-like growth factor 2
    • Factor
    • Growth
    • Insulin-like
    • Bp
    • Chr
    • Function
    • Gene
    • Ii
    • Protein
    • Chromosome
    • Human
    • Insulin
  • insulin-like growth factor 2
    • Factor
    • Growth
    • Insulin-like
    • Major
    • Bp
    • Chr
    • Function
    • Gene
    • Ii
    • Protein
    • Chromosome
    • Human
  • insulin-like growth factor 1
    • Factor
    • Growth
    • Insulin-like
    • Major
    • Bp
    • Chr
    • Function
    • Gene
    • Ii
    • Protein
    • Chromosome
    • Human
  • gene
    • Binding
    • Bp
    • Chr
    • Function
    • Protein
    • Chromosome
    • Expression
    • Human
    • External
    • Region
    • Band
    • Insulin-like
  • chromosome 11p
    • Bp
    • Human
    • Band
    • Function
    • Gene
    • External
    • Factor
    • Region
    • Insulin-like
    • Growth
    • Activity
    • Binding
  • homologous region
    • Binding
    • Function
    • Gene
    • Mice
    • Protein
    • Igf2
    • Chromosome
    • Ctcf
    • Expression
    • Band
    • Blood
    • Activity
  • non-islet hypoglycemic cell tumors
    • Hormone
    • Activity
    • Binding
    • Cell
    • Chr
    • Function
    • Gene
    • Ii
    • Memory
    • Protein
    • Tumors
    • Chromosome
  • gene structure
    • Binding
    • Bp
    • Chr
    • Function
    • Protein
    • Chromosome
    • Expression
    • Human
    • External
    • Region
    • Band
    • Insulin-like

Connections between topic areas Semantic bridges

For Insulin-like growth factor 2, one of the stronger structural bridges in this analysis connects Insulin-like growth factor 2 with Clinical relevance. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Insulin-like growth factor 2Clinical relevance · splits 31 ⟂ 11
Insulin-like growth factor 2Gene structure · splits 32 ⟂ 10
Insulin-like growth factor 2Function · splits 32 ⟂ 10
Insulin-like growth factor 2Overview · splits 36 ⟂ 6
Insulin-like growth factor 2Interactions · splits 38 ⟂ 4

Map overview Semantic statistics

Insulin-like growth factor 2

Nodes42
Edges41
Triples91
Avg. degree1.95
Density0.047619
Components1

Source & methodology

TTTA analyzes the structure around Insulin-like growth factor 2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Regions, Clinical relevance & Gene structure, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Insulin-like growth factor 2 · EN edition · Analysis: TopicsToTalkAbout

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