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KAT7 (gene)

Histone acetyltransferase KAT7 is an enzyme that in humans is encoded by the KAT7 gene. It specifically acetylates H4 histones at the lysine12 residue (H4K12) and is necessary for origin licensing and DNA replication. KAT7 associates with origins of replication during G1 phase of the cell cycle through complexing with CDT1. Geminin is thought to inhibit…

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InteractARMCM2ORC1LVIM
5 related topics

Overview

EnzymeGeneH4 histonesLysineOrigin licensing
11 related topics

Key facts & relationships

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2.3.1.48
↗
Aliases
KAT7, HBO1, HBOA, MYST2, ZC2HC7, lysine acetyltransferase 7
Band
17q21.33 · 11|11 D
Bgee
sural nerve · testicle · left testis · Achilles tendon · right testis
BioGPS
More reference expression data
Chr.
Chromosome 17 (human) · Chromosome 11 (mouse)

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KAT7 (gene)

Nodes19
Edges18
Triples100
Avg. degree1.89
Density0.105263
Components1

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KAT7 (gene)

Top relations

Gene ontology · 38
KAT7 (gene) → acyltransferase activity, chromatin organization, cytoplasm, cytosol, DNA replication, DNA replication origin binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, H4 histone acetyltransferase activity, histone acetylation, histone acetyltransferase activity, histone acetyltransferase complex, histone binding, histone H3 acetylation, histone H4-K12 acetylation, histone H4-K16 acetylation, histone H4-K5 acetylation, histone H4-K8 acetylation, internal peptidyl-lysine acetylation, metal ion binding
Bgee · 20
KAT7 (gene) → Achilles tendon, ankle joint, cumulus cell, epithelium of colon, gonad, granulocyte, left testis, popliteal artery, right testis, Rostral migratory stream, secondary oocyte, seminiferous tubule, spermatid, spermatocyte, sural nerve, tail of embryo, testicle, tibial arteries, ventricular zone, zygote
RNA expression pattern · 20
KAT7 (gene) → Achilles tendon, ankle joint, cumulus cell, epithelium of colon, gonad, granulocyte, left testis, popliteal artery, right testis, Rostral migratory stream, secondary oocyte, seminiferous tubule, spermatid, spermatocyte, sural nerve, tail of embryo, testicle, tibial arteries, ventricular zone, zygote
Band · 2
KAT7 (gene) → 11|11 D, 17q21.33
Chr. · 2
KAT7 (gene) → Chromosome 11 (mouse), Chromosome 17 (human)
End · 2
KAT7 (gene) → 49,835,026 bp, 95,201,072 bp
2.3.1.48 · 1
KAT7 (gene) → ↗
Aliases · 1
KAT7 (gene) → KAT7, HBO1, HBOA, MYST2, ZC2HC7, lysine acetyltransferase 7
BioGPS · 1
KAT7 (gene) → More reference expression data
Databases · 1
KAT7 (gene) → NCBI: entry; OMA: entry

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Important terminology

kat7 bp chr human band acetyltransferase gene chromosome 17 cdt1 replication activity location enzyme mouse histone h4 origin dna cell

Entity relationships Subject–Predicate–Object triples

SubjectPredicateObjectConfidenceSrc
KAT7 (gene)2.3.1.48↗1.00infobox
KAT7 (gene)AliasesKAT7, HBO1, HBOA, MYST2, ZC2HC7, lysine acetyltransferase 71.00infobox
KAT7 (gene)Band17q21.331.00infobox
KAT7 (gene)Band11|11 D1.00infobox
KAT7 (gene)Bgeesural nerve1.00infobox
KAT7 (gene)Bgeetesticle1.00infobox
KAT7 (gene)Bgeeleft testis1.00infobox
KAT7 (gene)BgeeAchilles tendon1.00infobox
KAT7 (gene)Bgeeright testis1.00infobox
KAT7 (gene)Bgeeventricular zone1.00infobox
KAT7 (gene)Bgeegonad1.00infobox
KAT7 (gene)Bgeeepithelium of colon1.00infobox
KAT7 (gene)Bgeepopliteal artery1.00infobox
KAT7 (gene)Bgeetibial arteries1.00infobox
KAT7 (gene)Bgeespermatocyte1.00infobox
KAT7 (gene)Bgeeankle joint1.00infobox
KAT7 (gene)BgeeRostral migratory stream1.00infobox
KAT7 (gene)Bgeezygote1.00infobox
KAT7 (gene)Bgeespermatid1.00infobox
KAT7 (gene)Bgeesecondary oocyte1.00infobox
KAT7 (gene)Bgeeseminiferous tubule1.00infobox
KAT7 (gene)Bgeetail of embryo1.00infobox
KAT7 (gene)Bgeecumulus cell1.00infobox
KAT7 (gene)Bgeegranulocyte1.00infobox
KAT7 (gene)BioGPSMore reference expression data1.00infobox
KAT7 (gene)Chr.Chromosome 17 (human)1.00infobox
KAT7 (gene)Chr.Chromosome 11 (mouse)1.00infobox
KAT7 (gene)DatabasesNCBI: entry; OMA: entry1.00infobox
KAT7 (gene)End49,835,026 bp1.00infobox
KAT7 (gene)End95,201,072 bp1.00infobox

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