Research any topic before you write.

Find related topics. | Discover entities. | See connections. | Build a topical map.

Vasoactive intestinal peptide: Function, Mechanisms & Overview

Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. VIP is produced in many tissues of vertebrates including the gut…

Language: English [EN]
Use the mouse wheel or two fingers (on touchscreens) to zoom in and out of the map.
100%
More settings
100% 100% 100% 100% 100%

Vasoactive intestinal peptide topic overview

The analysis highlights Function, Mechanisms and Overview as prominent areas in the source structure around Vasoactive intestinal peptide.

Related topics
66
Source areas
5
Connected nodes
71
Extracted relationships
98
Concept neighborhoods
26
Bridge connections
71

What this topic covers Research coverage

Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.

Function · 22 topics
Overview · 22 topics
Mechanisms · 18 topics
Pathology · 2 topics
Social behavior · 2 topics

Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.

Key facts & relationships

High-confidence facts extracted from structured source data. Use them as anchors for further research.

Aliases
VIP, vasoactive intestinal peptide, PHM27
Available structures
Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RRI, 2RRH
Band
6q25.2 · 10|10 A1
Bgee
appendix · rectum · gonad · muscle layer of sigmoid colon · testicle
BioGPS
More reference expression data
Chr.
Chromosome 6 (human) · Chromosome 10 (mouse)

Explore all related topics Closing gaps

Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.

Overview

Function

Mechanisms

Social behavior

Pathology

Advanced semantic analysis

Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.

How Vasoactive intestinal peptide connects Entity context

The extracted context around Vasoactive intestinal peptide shows recurring relationship patterns in the source. For example, Vasoactive intestinal peptide → adenylate cyclase-activating G protein-coupled receptor signaling pathway, antimicrobial humoral immune response mediated by antimicrobial peptide, body fluid secretion, epinephrine secretion, extracellular region, G protein-coupled receptor signaling pathway, hormone activity, innate immune response, intracellular anatomical structure, learning or memory, mRNA stabilization, negative regulation of apoptotic process, negative regulation of potassium ion transport, negative regulation of smooth muscle cell proliferation, neuron projection, neuropeptide hormone activity, peptide hormone receptor binding, perikaryon, phospholipase C-activating G protein-coupled receptor signaling pathway, positive regulation of cell population proliferation Another extracted example is Vasoactive intestinal peptide → anterior cingulate cortex, appendix, barrel cortex, cingulate gyrus, duodenum, endothelial cell, gastric mucosa, gonad, ileum, left colon, muscle layer of sigmoid colon, Paneth cell, prefrontal cortex, primary visual cortex, pyloric antrum, rectum, superior frontal gyrus, suprachiasmatic nucleus, testicle, transverse colon. Use these groups to spot repeated connection types before inspecting the individual relationships.

Vasoactive intestinal peptide

Top relations

Gene ontology · 29
Vasoactive intestinal peptide → adenylate cyclase-activating G protein-coupled receptor signaling pathway, antimicrobial humoral immune response mediated by antimicrobial peptide, body fluid secretion, epinephrine secretion, extracellular region, G protein-coupled receptor signaling pathway, hormone activity, innate immune response, intracellular anatomical structure, learning or memory, mRNA stabilization, negative regulation of apoptotic process, negative regulation of potassium ion transport, negative regulation of smooth muscle cell proliferation, neuron projection, neuropeptide hormone activity, peptide hormone receptor binding, perikaryon, phospholipase C-activating G protein-coupled receptor signaling pathway, positive regulation of cell population proliferation
Bgee · 20
Vasoactive intestinal peptide → anterior cingulate cortex, appendix, barrel cortex, cingulate gyrus, duodenum, endothelial cell, gastric mucosa, gonad, ileum, left colon, muscle layer of sigmoid colon, Paneth cell, prefrontal cortex, primary visual cortex, pyloric antrum, rectum, superior frontal gyrus, suprachiasmatic nucleus, testicle, transverse colon
RNA expression pattern · 20
Vasoactive intestinal peptide → anterior cingulate cortex, appendix, barrel cortex, cingulate gyrus, duodenum, endothelial cell, gastric mucosa, gonad, ileum, left colon, muscle layer of sigmoid colon, Paneth cell, prefrontal cortex, primary visual cortex, pyloric antrum, rectum, superior frontal gyrus, suprachiasmatic nucleus, testicle, transverse colon
Band · 2
Vasoactive intestinal peptide → 10|10 A1, 6q25.2
Chr. · 2
Vasoactive intestinal peptide → Chromosome 10 (mouse), Chromosome 6 (human)
End · 2
Vasoactive intestinal peptide → 152,759,765 bp, 5,597,617 bp
Aliases · 1
Vasoactive intestinal peptide → VIP, vasoactive intestinal peptide, PHM27
Available structures · 1
Vasoactive intestinal peptide → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RRI, 2RRH
BioGPS · 1
Vasoactive intestinal peptide → More reference expression data
Databases · 1
Vasoactive intestinal peptide → NCBI: entry; OMA: entry

Important terminology

Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.

Important terminology

vip scn circadian also peptide bp gene human role brain vpac2 rhythm secretion intestinal chr band function vasoactive neurons prolactin

Vasoactive intestinal peptide relationships Subject–Predicate–Object triples

TTTA extracted 98 structured relationships around Vasoactive intestinal peptide. Examples in this analysis include Vasoactive intestinal peptide → Aliases → VIP, vasoactive intestinal peptide, PHM27 and Vasoactive intestinal peptide → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RRI, 2RRH. The table shows each extracted connection, where it came from and its confidence.

SubjectPredicateObjectConfidenceSrc
Vasoactive intestinal peptideAliasesVIP, vasoactive intestinal peptide, PHM271.00infobox
Vasoactive intestinal peptideAvailable structuresAvailable structuresPDBOrtholog search: PDBe RCSB List of PDB id codes2RRI, 2RRH1.00infobox
Vasoactive intestinal peptideBand6q25.21.00infobox
Vasoactive intestinal peptideBand10|10 A11.00infobox
Vasoactive intestinal peptideBgeeappendix1.00infobox
Vasoactive intestinal peptideBgeerectum1.00infobox
Vasoactive intestinal peptideBgeegonad1.00infobox
Vasoactive intestinal peptideBgeemuscle layer of sigmoid colon1.00infobox
Vasoactive intestinal peptideBgeetesticle1.00infobox
Vasoactive intestinal peptideBgeegastric mucosa1.00infobox
Vasoactive intestinal peptideBgeeendothelial cell1.00infobox
Vasoactive intestinal peptideBgeetransverse colon1.00infobox
Vasoactive intestinal peptideBgeecingulate gyrus1.00infobox
Vasoactive intestinal peptideBgeeanterior cingulate cortex1.00infobox
Vasoactive intestinal peptideBgeesuprachiasmatic nucleus1.00infobox
Vasoactive intestinal peptideBgeePaneth cell1.00infobox
Vasoactive intestinal peptideBgeeprefrontal cortex1.00infobox
Vasoactive intestinal peptideBgeeleft colon1.00infobox
Vasoactive intestinal peptideBgeeprimary visual cortex1.00infobox
Vasoactive intestinal peptideBgeeduodenum1.00infobox
Vasoactive intestinal peptideBgeebarrel cortex1.00infobox
Vasoactive intestinal peptideBgeesuperior frontal gyrus1.00infobox
Vasoactive intestinal peptideBgeepyloric antrum1.00infobox
Vasoactive intestinal peptideBgeeileum1.00infobox
Vasoactive intestinal peptideBioGPSMore reference expression data1.00infobox
Vasoactive intestinal peptideChr.Chromosome 6 (human)1.00infobox
Vasoactive intestinal peptideChr.Chromosome 10 (mouse)1.00infobox
Vasoactive intestinal peptideDatabasesNCBI: entry; OMA: entry1.00infobox
Vasoactive intestinal peptideEnd152,759,765 bp1.00infobox
Vasoactive intestinal peptideEnd5,597,617 bp1.00infobox

Related concept clusters Concept neighborhoods

The concept neighborhoods around Vasoactive intestinal peptide bring nearby vocabulary together. In this analysis, examples include Peptide, Vasoactive and Pathway. Use the clusters to find adjacent concepts and terminology that may deserve separate research.

  • Vasoactive intestinal peptide
    • Peptide
    • Vasoactive
    • Pathway
    • Gene
    • Body
    • Hormone
    • Also
    • Chromosome
    • Heart
    • Location
    • Muscle
    • Pituitary
  • vasoactive intestinal peptide
    • Peptide
    • Vasoactive
    • Pathway
    • Gene
    • Body
    • Hormone
    • Chromosome
    • Location
    • Signaling
    • Bp
    • Chr
    • Human
  • peptide hormone
    • Vasoactive
    • Pathway
    • Gene
    • Intestinal
    • Body
    • Hormone
    • Peptide
    • Secretion
    • Chromosome
    • Location
    • Signaling
    • Bp
  • brain
    • Body
    • Suprachiasmatic
    • Location
    • Scn
    • Vip
    • Circadian
    • Pathway
    • Chromosome
    • Heart
    • Hypothalamus
    • Many
    • Signaling
  • gene
    • Chromosome
    • Location
    • Bp
    • Chr
    • Human
    • Intestinal
    • Peptide
    • Body
    • Pathway
    • Band
    • Signaling
    • Vasoactive
  • scn and circadian rhythm
    • Rhythm
    • Scn
    • Vip
    • Neurons
    • Role
    • Location
    • Activity
    • Function
    • Gene
    • Pathway
    • Signaling
    • Social
  • brain cells
    • Body
    • Suprachiasmatic
    • Location
    • Scn
    • Vip
    • Circadian
    • Pathway
    • Chromosome
    • Heart
    • Hypothalamus
    • Many
    • Receptor
  • function
    • Body
    • Pathway
    • Chromosome
    • Location
    • Signaling
    • Bp
    • Chr
    • Human
    • Intestinal
    • Gene
    • Peptide
    • Secretion

Connections between topic areas Semantic bridges

For Vasoactive intestinal peptide, one of the stronger structural bridges in this analysis connects Vasoactive intestinal peptide with Overview. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.

Min side: 3
Vasoactive intestinal peptideOverview · splits 49 ⟂ 23
Vasoactive intestinal peptideFunction · splits 49 ⟂ 23
Vasoactive intestinal peptideMechanisms · splits 53 ⟂ 19
Vasoactive intestinal peptideSocial behavior · splits 69 ⟂ 3
Vasoactive intestinal peptidePathology · splits 69 ⟂ 3

Map overview Semantic statistics

Vasoactive intestinal peptide

Nodes72
Edges71
Triples98
Avg. degree1.97
Density0.027778
Components1

Source & methodology

TTTA analyzes the structure around Vasoactive intestinal peptide to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Mechanisms & Overview, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.

Source: Wikipedia — Vasoactive intestinal peptide · EN edition · Analysis: TopicsToTalkAbout

For writers, content strategists, SEOs, marketers and creators — from quick topic research to advanced semantic analysis.