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PER2 is a protein in mammals encoded by the PER2 gene. PER2 is noted for its major role in circadian rhythms.
The analysis highlights Function, Discovery and Clinical significance as prominent areas in the source structure around PER2.
Source areas are shown by the number of related topics found in each part of the analysis. Use smaller areas too: they can reveal specialized angles and content gaps.
Smaller areas are not necessarily less important. They contain fewer connections in this analysis and can be useful for finding specialized angles or coverage gaps.
High-confidence facts extracted from structured source data. Use them as anchors for further research.
Browse the complete topic structure, not only the most central items. Less prominent entities and concepts can reveal missing angles, specialized context and useful research gaps. Each item opens a new analysis centered on that subject.
Deeper signals for content research, entity SEO and topical coverage. The plain-language headings explain what each technical view is useful for.
The extracted context around PER2 shows recurring relationship patterns in the source. For example, PER2 → circadian regulation of gene expression, circadian regulation of translation, circadian rhythm, cytoplasm, entrainment of circadian clock by photoperiod, fatty acid metabolic process, gluconeogenesis, glycogen biosynthetic process, histone H3 deacetylation, lactate biosynthetic process, negative regulation of circadian rhythm, negative regulation of fat cell proliferation, negative regulation of protein ubiquitination, negative regulation of transcription by RNA polymerase II, negative regulation of transcription regulatory region DNA binding, negative regulation of transcription, DNA-templated, nucleolus, nucleus, perinuclear region of cytoplasm, positive regulation of cold-induced thermogenesis Another extracted example is PER2 → adrenal gland, bronchial epithelial cell, caput epididymis, granulocyte, lacrimal gland, left lung lobe, lobe of cerebellum, median eminence, mucosa of paranasal sinus, nasal epithelium, oocyte, palpebral conjunctiva, primary motor cortex, rectum, respiratory epithelium, secondary oocyte, skin of thigh, suprachiasmatic nucleus, tail of epididymis, urethra. Use these groups to spot repeated connection types before inspecting the individual relationships.
Use these terms to understand the vocabulary surrounding the topic, not as a checklist for keyword stuffing.
circadian gene human protein clock bp mouse period expression chr band chromosome also ck1e levels mice mutation nucleus sleep expressed
TTTA extracted 157 structured relationships around PER2. Examples in this analysis include PER2 → Aliases → PER2, FASPS, FASPS1, period circadian clock 2, period circadian regulator 2 and PER2 → Available structures → Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3GDI, 4CT0, 4U8H. The table shows each extracted connection, where it came from and its confidence.
| Subject | Predicate | Object | Confidence | Src |
|---|---|---|---|---|
| PER2 | Aliases | PER2, FASPS, FASPS1, period circadian clock 2, period circadian regulator 2 | 1.00 | infobox |
| PER2 | Available structures | Available structuresPDBOrtholog search: PDBe RCSB List of PDB id codes3GDI, 4CT0, 4U8H | 1.00 | infobox |
| PER2 | Band | 2q37.3 | 1.00 | infobox |
| PER2 | Band | 1|1 D | 1.00 | infobox |
| PER2 | Bgee | oocyte | 1.00 | infobox |
| PER2 | Bgee | mucosa of paranasal sinus | 1.00 | infobox |
| PER2 | Bgee | secondary oocyte | 1.00 | infobox |
| PER2 | Bgee | bronchial epithelial cell | 1.00 | infobox |
| PER2 | Bgee | palpebral conjunctiva | 1.00 | infobox |
| PER2 | Bgee | nasal epithelium | 1.00 | infobox |
| PER2 | Bgee | tail of epididymis | 1.00 | infobox |
| PER2 | Bgee | urethra | 1.00 | infobox |
| PER2 | Bgee | caput epididymis | 1.00 | infobox |
| PER2 | Bgee | skin of thigh | 1.00 | infobox |
| PER2 | Bgee | adrenal gland | 1.00 | infobox |
| PER2 | Bgee | left lung lobe | 1.00 | infobox |
| PER2 | Bgee | suprachiasmatic nucleus | 1.00 | infobox |
| PER2 | Bgee | granulocyte | 1.00 | infobox |
| PER2 | Bgee | rectum | 1.00 | infobox |
| PER2 | Bgee | lacrimal gland | 1.00 | infobox |
| PER2 | Bgee | median eminence | 1.00 | infobox |
| PER2 | Bgee | primary motor cortex | 1.00 | infobox |
| PER2 | Bgee | lobe of cerebellum | 1.00 | infobox |
| PER2 | Bgee | respiratory epithelium | 1.00 | infobox |
| PER2 | BioGPS | More reference expression data | 1.00 | infobox |
| PER2 | Chr. | Chromosome 2 (human) | 1.00 | infobox |
| PER2 | Chr. | Chromosome 1 (mouse) | 1.00 | infobox |
| PER2 | Databases | NCBI: entry; OMA: entry | 1.00 | infobox |
| PER2 | End | 238,290,102 bp | 1.00 | infobox |
| PER2 | End | 91,387,046 bp | 1.00 | infobox |
The concept neighborhoods around PER2 bring nearby vocabulary together. In this analysis, examples include Expression, Gene and Human. Use the clusters to find adjacent concepts and terminology that may deserve separate research.
For PER2, one of the stronger structural bridges in this analysis connects PER2 with Function. Bridges highlight paths between different parts of the map and can reveal research angles that are easy to miss in a flat list.
TTTA analyzes the structure around PER2 to surface related topics, entities, relationships, concept neighborhoods and bridge connections. Use the map to explore areas such as Function, Discovery & Clinical significance, including less central topics that may reveal useful research gaps. Automatically extracted connections are research leads rather than rewritten encyclopedia content.
Source: Wikipedia — PER2 · EN edition · Analysis: TopicsToTalkAbout